Medicinal product 'Polyoxidonium' (candles) .Responses.

"Polyoxidonium" - a drug that is used to treat chronic inflammatory diseases of any origin in the stages of exacerbation, remission; For the treatment of rheumatoid arthritis, various forms of tuberculosis. The drug is also used after chemo -, radiotherapy tumors. It is effective for the treatment of acute, chronic forms of bacterial, viral infections (cystitis, urethritis, prostatitis, pyelonephritis, salpingoophoritis, colpitis, endometritis). Sometimes a drug is used to correct immunodeficiencies (secondary), to rehabilitate long and often sick people, to activate regeneration processes after burns, fractures, trophic ulcers. The main form of release - suppositories.

The drug contains the active substance polyoxidonium. Auxiliary components: povidone, mannitol, betacarotene, cocoa butter.

The preparation "Polyoxidonium" (candles), experts' reviews confirm this, has a high level of bioavailability. It reaches a maximum concentration in the blood plasma one hour after use. The half-life period (this is a fast phase) is about thirty minutes. It is excreted by the kidneys after metabolism to oligomers.

The drug "Polyoxidonium" (candles), reviews of pharmacologists testify to its effectiveness, has pronounced immunomodulating effects, increases the body's resistance against local, generalized infections. The basis of its action is the effect on phagocytic cells, stimulation of antibody formation. The drug restores immune responses during secondary immunodeficiencies, which are caused by various traumas, infections, malignant neoplasms, burns; After surgical interventions, as well as the use of steroid hormones, cytotoxic drugs). The drug also has a detoxification effect: it increases the resistance of cellular membranes to the toxic effects of drugs, chemicals. The drug, patient feedback confirms this, is well tolerated, is not capable of exhibiting mitogenic, polyclonal activity. It does not cause mutagenic, allergic, teratogenic, embryotoxic effects.

The immunomodulator "Polyoxidonium" can be applied intaginally, rectally. Method of use, the dosage is determined by the doctor and depends on body weight, diagnosis, severity, severity of the disease, age of the patient. When rectal administration, one candle is used at night after pre-emptying the intestine. After three days, the intake is reduced to one suppository within two days. Invaginally, the drug is used to treat chronic solpingoophoritis, colpitis, salpingitis, dysplasia, leukoplakia, ectopia of the cervix. One suppository per day is taken. The course of therapy is ten days. If necessary, you can repeat the drug. Supportive treatment is indicated for patients with chronic forms of immune deficiency (two candles per week). It must be done constantly.

The drug "Polyoxidonium" (candles), the patients' testimonials confirm this, has no significant side effects. Contraindications include hypersensitivity to individual components of the drug, the period of pregnancy. In the presence of acute renal failure, the drug should be used with extreme caution. In this case, it will be expedient to abandon the use of the preparation "Polyoxidonium" (candles). An analogue of this drug can be used if it has improved pharmacological properties.

Among drug interactions, there is an increased effect when combined with antiviral, antihistamine, antifungal drugs, antibiotics, cytostatics, glucocorticosteroids.

The drug "Polyoxidonium" (candles), experts' reviews confirm, does not cause symptoms of an overdose, is absolutely safe. However, do not use it in excessively large quantities.