The preparation "Spironolactone". Instructions for use

The drug "Spironolactone" is a potassium- and magnesium-saving diuretic. Therapeutic efficacy of the remedy is noted on the second - fifth day of admission. The drug is good absorbability (absorbed by 90%). Metabolism of the drug occurs in the liver, excretion - through the kidneys and with bile (in a small amount).

Means "Spironolactone". Instructions for use: indications

The medication is prescribed for secondary hyperaldosteronism on the soil of cirrhosis, complicated by edema and ascites, with nephrotic syndrome. The drug is indicated for essential hypertension (in complex treatment), hypomagnesemia and hypokalemia (as an auxiliary for prophylaxis against therapy and with the inability to use other medications to adjust the potassium level). The drug is prescribed for oedematous syndrome, provoked by cardiac failure of the chronic course. In this case, the agent can be used for monotherapy or in complex treatment. The medication is prescribed with hyperaldosteronism and for a short reception before the operation.

The medicine "Spironolactone". Instructions for use

With essential hypertension, adults are prescribed 50-100 mg once. It is allowed to increase the dose to 200 mg. The dosage is increased every fourteen days. To obtain a therapeutic effect, the medication is taken for at least two weeks. In accordance with the state, the reception circuit is corrected. With idiopathic hyperaldosteronism, the dosage is 100-400 mg per day. With hypokalemia and hypomagnesemia, the preparation "Spironolactone" recommends the use of the instruction for 25-100 mg once or several times a day. A day should not drink more than 400 mg. Against the background of hyperaldosteronism and hypokalemia of the marked course, 300 mg 2-3 times / day are prescribed. When the condition is eased, the dosage is reduced to 25 mg / day. The course of preoperative therapy is carried out, appointing 400 mg for four days. In the absence of indications for intervention, maintenance treatment is recommended in the lowest therapeutically effective dosage. The reception scheme in this case is established personally. In the treatment of edema, provoked by nephrotic syndrome, 100-200 mg is prescribed.

The preparation "Spironolactone". Instructions for use: adverse reactions

The medicine can provoke diarrhea, megaloblasticosis, intestinal colic, abdominal pain, alkalosis or acidosis, dizziness, bleeding and gastrointestinal ulcers, hyperuricemia. On the basis of treatment, there may be an increase in the level of urea, hypercreatinemia, lethargy, drowsiness, headache. When taking medication, thrombocytopenia, gynecomastia (against a background of prolonged therapy) may occur. In men with the drug "Spironolactone" (reviews confirm this), probably an erection disorder. In women, metrorrhagia is possible during menopause, coarsening of the voice, carcinoma and soreness in the mammary glands, dysmenorrhea. The negative consequences include allergy, itching, rashes, muscle spasms - this is indicated by the instruction on application attached to the preparation "Spironolactone". The price of the medicine is about 100 rubles.