Medication "Indapamide retard": features of use

Description of pharmacodynamics of the preparation

Medication "Indapamid retard" is an antihypertensive drug, its pharmacological characteristics are close to the group of thiazide diuretics. This drug has the ability to selectively block the so-called calcium channels, increasing the release of urine ions of magnesium, chlorine, sodium and potassium. In addition, the drug "Indapamide retard" reduces peripheral vascular resistance, increases the elasticity of the walls of blood vessels and reduces hypertrophy of the left ventricle. It is especially worth noting that this antihypertensive drug has no effect on carbohydrate and lipid metabolism, and also does not impair the susceptibility of peripheral tissues to insulin. The main indication for the use of the drug is arterial hypertension, with the hypotensive effect develops after seven days of continuous use and persists for twenty-four hours against the background of a single use of the indapamide retard. The price of this drug varies within the limits of thirty-one hundred rubles depending on the specific dosage.

Features of the composition of the drug

The indapamide retard drug is available in the form of white biconvex tablets, as an active ingredient containing 1.5 milligrams of indapamide. In the role of additional components are milk sugar, hypromellose, lactose monohydrate, silicon dioxide, magnesium stearate, titanium dioxide, Opadrai II and polyethylene glycol.

Scheme of application and dosage

Take the drug "Indapamide retard" instruction advises in the morning hours in dosage - one tablet a day. In this case, the administration of this antihypertensive agent can be carried out independently of the ingestion of food. If the desired therapeutic result is not achieved, after four to eight weeks of therapy, the dosage of the drug should not be increased, in order to avoid an increase in the risk of undesirable side effects. Instead, another antihypertensive medication other than a thiazide diuretic is included in the treatment regimen.

The main contraindications to the appointment

Take the drug "Indapamide Retard" is not recommended in case the patient has hypokalemia, kidney failure, liver failure and individual intolerance to lactose and sulfonamide derivatives. During breastfeeding, during pregnancy, as well as with galactosemia and a violation of the absorption of galactose, you should not similarly use this drug. Patients under the age of eighteen also should not take the tablet "Indapamide retard." With extreme caution this antihypertensive drug is prescribed for violations in the kidney and liver, hyperparathyroidism, diabetes mellitus, hyperuricemia and severe disturbances in the water-electrolyte balance.