Pharmaceutical preparation "Papaverin" (candles). Instructions for use

Pharmaceutical preparation "Papaverin" (suppositories) instructions for use are included in the clinical and pharmacological group of myotropic antispasmodics.

This medication has antihypertensive and antispasmodic effect. It contributes to a significant decrease in tone and relaxation of smooth muscles in the digestive tract, respiratory and genitourinary systems, reduces the content of calcium ions.

With the receipt of an increased amount of the drug in question, myocardial relaxation and a decrease in the rate of blood flow are noted. The medication has no particular effect on the central nervous system.

The drug "Papaverin" (candles), instruction for use notes, is characterized by rapid absorption. In blood plasma, it binds to proteins. It is established that this drug easily overcomes the histohematological barrier. He is biotransformed in the liver. The half-life can range from thirty minutes to two hours.

Each suppository contains 0.02 grams of papaverine hydrochloride.

The drug "Papaverin". Application

This drug is used to eliminate spasms of smooth muscles in the organs of the abdominal cavity - cholecystitis, pilorospasm, spastic colitis, renal colic, as well as with angina pectoris, spasms of the brain. In addition, the drug is used as an auxiliary for premedication.

The drug "Papaverin" (suppositories), the instruction for use informs, is contraindicated in case of hypersensitivity of the patient to the components of the drug, AV blockade, glaucoma, severe renal failure, in the elderly and children.

With special care this drug is prescribed for conditions after receiving a craniocerebral injury, as well as with chronic renal failure in chronic form, hypothyroidism, prostatic hyperplasia, supraventricular tachycardia.

The drug "Papaverin" (candles), the instruction manual especially notes, can cause some undesirable effects, among which are the following:

• Some disorders of the cardiovascular system, such as AV blockade, lower blood pressure, ventricular extrasystole ;
• Disruptions in the functioning of the digestive system - loose stools, constipation, activation of hepatic transaminases;
• In addition, it is possible the development of drowsiness, allergic reactions, eosinophilia.

In combination with barbiturates, the spasmolytic effect exerted by the drug under consideration is enhanced. Its antihypertensive effect is increased when combined with antidepressants (tricyclics), reserpine, quinidine and procainamide.

Symptoms of overdose are: double vision and other visual impairments, drowsiness, weakness, lowering of blood pressure. The necessary treatment is immediate gastric lavage and maintenance of blood pressure.

Adult patients are shown one to two suppositories (twenty to forty milligrams) maximum three times a day. This form of the drug is the most optimal in situations when the use of oral means is difficult (with diarrhea or vomiting). In addition, it is the suppositories that are shown to persons suffering from impaired functioning of the organs of the gastrointestinal tract.

The drug "Papaverin" with the tone of the uterus in a woman in the position makes it possible to improve the blood supply of the musculature of this organ, and this has a positive effect on the fetal condition, reduces the risk of miscarriage.

It is established that the effectiveness of the medication is reduced when the patient smokes. For the period of treatment should completely abandon the use of alcoholic beverages.