Lornoxicam: instructions for use, reviews, analogues

Diseases that are accompanied by pain and inflammation, can hardly be considered a rarity in modern medicine. Naturally, there are thousands of different anti-inflammatory and anesthetic drugs that can eliminate discomfort. One of them is the medicine "Lornoxicam". Instructions for use in this case is quite simple, and doctors often recommend this tool. But what is the drug? How to apply it correctly? Are there any complications? These questions are asked by many patients.

Composition and form of the drug

This drug is available in two forms: tablets and powder for the preparation of injections.

In the pharmacy you can buy small rounded tablets with a hard film shell of white, sometimes yellowish color. The main active substance is lornoxicam. The drug may have a different dosage of 4 or 8 mg of the active ingredient. One blister contains 10 tablets, and in the package there can be 1 or 3 such blisters. As auxiliary components, such substances as talc, lactose, hydromellose, titanium dioxide, magnesium stearate, polyvidone K25 and croscarmellose sodium are present here.

There is also a lyophilizate for the preparation of injections, which is a dense mass of yellow, placed in a hermetic glass bottle. The active substance is also lornoxicam (dosage - 8 mg). As auxiliary substances, disodium edetate, as well as mannitol E-421 and trometamol are present here.

Main pharmacological properties

This drug is a non-steroidal anti-inflammatory drug, belonging to the class of oxicams. The active substance of the drug inhibits the activity of the COX-2 isoenzyme, which, in turn, slows the synthesis of prostaglandins. Thus, the drug slows down the development of the inflammatory process.

In addition, this agent inhibits the release of free oxygen radicals from activated leukocytes. The drug also has a pronounced analgesic effect.

Pharmacodynamics of the preparation

Tablets "Lornoxicam" are well absorbed in the gastric tract, after it enter the blood, where approximately 99% are bound to plasma proteins. By the way, if you take the drug with food, then the maximum concentration in the blood drops by about 30%. Bioavailability of the drug is 99-100%. The half-life is relatively short and is four hours.

The processes of metabolism of the drug's active substances occur in the liver tissues. The drug does not induce the induction of liver enzymes. Metabolites are excreted through the intestine and kidneys (approximately 30% of the total).

Main indications for use

In fact, the drug is widely used to remove almost any type of pain. For example, it becomes an indispensable companion for people suffering from arthritis, including infectious, rheumatoid, acute gouty and psoriatic forms of the disease. In addition, the drug effectively removes inflammation and soreness in ischialgia, deforming osteoarthritis, osteochondrosis, and radicular syndrome.

Tablets are also prescribed to relieve dental, menstrual and severe muscle pain. Injections are widely used in medicine to eliminate post-traumatic and post-operative pain.

Lornoxicam tablets: instructions for use

If there is inflammation and pain, it is urgent to see a doctor. It is not recommended to use any drugs autocratically, as a professional medical examination is necessary for a start. Only the attending physician can prescribe pills "Lornoxicam". The instructions for use contain only general recommendations and are intended only for reference.

Typically, doctors recommend taking one tablet two or three times a day (depending on the content of the active substance). The maximum allowable dose is 16 mg of the active substance. The length of the course of treatment is determined by the doctor. Although the drug does not normally accumulate in the body, long-term therapy requires constant monitoring, in particular, verification of peripheral blood, clotting level, etc.

The drug "Lornoxicam": instructions for use, injections

If the doctor has given you injections, then first you need to prepare a solution. To do this, you need to collect 2 ml of purified water for injections into a clean syringe and insert it into the vial using a needle. Shake it thoroughly until a uniform solution is formed. After that, take the medicine in a new syringe, change the needle. The injection should be carried out immediately after the preparation of the solution.

The drug can be administered both intramuscularly and intravenously. In some cases, the injection may be painful, but this can be avoided. If you enter the drug inside the muscle, then the duration of the procedure should exceed 5 seconds. In a vein, one dose of the drug should be administered for 15 seconds.

Dosage in this case, again, determines the doctor. As a rule, 8 mg of active substance (the contents of one vial) is administered to the patient once. With really severe pain, the procedure can be repeated again. But it is worth remembering that the maximum daily dose is 16 mg lornoxicam, and exceed it is strictly prohibited.

In some cases, patients need additional examinations. For example, in the presence of hypertension of mild or moderate severity, it is extremely important to monitor the arterial pressure throughout the course of treatment. Patients with impaired renal function should be constantly supervised by medical personnel and regularly tested for kidney function.

Are there any contraindications to therapy?

Do all categories of patients can use the drug "Lornoxicam"? Instruction for use indicates that there are contraindications to therapy, although there are not so many of them:

1. First of all it is necessary to note a hypersensitivity to components - in such patients the risk of development of an allergic reaction is increased.
2. The drug also has some age limitations - it can not be taken by children and adolescents under 18 years old, as well as elderly people.
3. Contraindications include periods of pregnancy and lactation.
4. The medicine can not be taken with certain diseases of the digestive tract, including ulcerative lesions, inflammation of the intestine, acute bleeding.
5. Violation of the liver and kidneys is also a limitation to this type of therapy.
6. Among other contraindications include severe forms of hypertension, congestive heart failure, as well as leukopenia and prostaglandin bronchial asthma.

Possible adverse reactions

Immediately it is worth noting that the drug "Lornoxicam" rarely causes any complications. On the other hand, completely eliminate the likelihood of their appearance can not be, so it is worth familiar with the list of side effects:

1. Most often, the medicine acts on the digestive system. Some patients complain of recurring nausea, as well as abdominal pain, vomiting, and stool disorders. Much less often there is dryness in the mouth, flatulence. Among the most rare adverse reactions include violations of the liver, intestinal bleeding, the formation of peptic ulcers, gastritis and esophagitis.
2. Sometimes the appearance of allergic reactions, which are most often accompanied by skin rashes, hives, itching, redness, swelling, and more rarely - dyspnoea and increased heart rate.
3. Perhaps the effect of the drug on the nervous system, which is manifested in periodic headaches, dizziness, conditions of increased excitation, sleep disorders.
4. Occasionally, the medicine affects metabolism, which is accompanied by a change in body weight, increased sweating, chills.
5. In some cases, a change in the blood clotting system is observed against the background of therapy, which is accompanied by nasal and hemorrhoidal hemorrhages.

Overdose, its symptoms and treatment

Many patients are interested in questions about whether it is possible to overdose drugs "Lornoxicam". The instruction indicates that such cases are observed, but extremely rarely and, as a rule, are associated with impaired metabolism of the patient or uncontrolled administration of medications.

The first symptoms of an overdose are nausea and vomiting. Later, some cerebral signs may appear, including severe dizziness and ataxia. In the most severe cases, this condition goes into convulsions and even to whom. To results of an overdosage it is possible to carry serious violations of coagulability of a blood, and also lesions of a liver and kidneys.

A patient with similar symptoms should be rushed to the hospital. Unfortunately, there is no specific antidote for today. Gastric lavage and activated charcoal intake are effective only if the drug has not yet been absorbed. Due to a small period of decay, the active substances are quickly removed from the body. In the presence of seizures and other complications, symptomatic therapy is performed.

How much does the drug cost?

Of course, for many patients, the important factor in choosing a medicine is the price. It should be understood that the figure will fluctuate depending on the form of release and dosage, as well as the city of residence, the manufacturer, the pharmacy you chose, etc.

So how much is the drug "Lornoxicam"? Injections, or rather, 5 bottles for the preparation of a solution, will cost approximately 800-950 rubles. Tablets are a little cheaper. For example, a drug with a dosage of 4 mg costs 150-200 (10 tablets) or 350-450 (30 tablets). But "Lornoxicam 8 mg" will cost about 200-250 rubles for ten tablets. Packing of 30 pieces costs approximately 550-650 rubles.

Are there any effective counterparts?

For one reason or another, not all patients are eligible for Lornoxicam. Analogues of the medicine, of course, exist. Some of them are even cheaper, and they are easier to get in the pharmacy. For example, "Xefokam", "Lornoxicam" and "Xefokam Rapid" - is, in fact, the same medicine with the same constituent substances, but only from different manufacturers.

There are other substitutes. For example, "Lorak" is considered to be quite effective, which also provides an anesthetic and anti-inflammatory effect. In any case, you should not self-medicate and arbitrarily exclude from the course of therapy the drug "Lornoxicam". Analogues can be chosen only by the attending physician. It will adjust the dosage and mode of reception, if necessary.

Reviews of doctors and patients about the drug

For patients who have been prescribed the drug "Lornoxicam", feedback from patients and professionals is a very important source of information. To begin with it is worth noting the positive opinion of doctors. This drug really quickly removes soreness and helps to cope with inflammation, therefore it is widely used in various branches of medicine. In addition, despite a rather impressive list of side effects, in fact they are recorded relatively rarely.

What do patients say about the drug "Lornoxicam"? Reviews in this case are also mostly positive. Both pills and injections help to quickly cope with the pain, and the effect from them can last up to ten hours. The injections are accompanied only by slight discomfort, especially if you follow all the instructions. Perhaps the only drawback is relatively high cost, especially when it comes to injectable solutions - not everyone can afford it. Nevertheless, the medicine is acting in effect and worth the money.