Sandimmun neoral - indications for use

Sandimmun neoral is adopted so that there is no rejection of the transplanted organ, for example, heart, liver, kidney, pancreas or lung. Also, this drug is prescribed for diseases such as acute non-infectious uveitis, when there is a threat of vision loss, with chronic glomerulonephritis, which is accompanied by the development of nephrotic syndrome. Also, sandimmun neoral is used in the treatment of rheumatoid arthritis with a high degree of activity, severe forms of atopic dermatitis and psoriasis.

Sandimmun neoral - application instructions

Treatment with this drug should be carried out only in medical institutions by high-level specialists. They should have experience of treatment with immunosuppressants. The use of sandimmun neoral requires constant monitoring of plasma creatinine level. It is also necessary to carry out constant monitoring of blood pressure, check and control the level of potassium in the blood. During the treatment, sandimune neoral is categorically contraindicated in carrying out vaccination with any attenuated vaccines. After the course of treatment for three months and non-receipt of positive results, you must stop using this drug and look for alternative ones. When preparing the infusion solution, use only glass containers.

Possible side effects

The use of this drug, as well as almost all the others, can have side effects. This may be interstitial renal fibrosis, acute and chronic renal failure, convulsive seizures, paresthesia, impaired liver function, arterial hypertension, vomiting, nausea, abdominal pain, weakness, myopathy, pancreatitis, diarrhea, hypertrichosis, anemia, fluid retention, Hyperuricemia, gingival hyperplasia, thrombocytopenia, headache, anorexia and increased susceptibility to infections.

In some cases, overdose can cause muscle spasms and muscle weakness, there is a deterioration of vision and impaired consciousness.

In some patients, during the overdose of this drug, lymphoproliferative disorders appeared and the development of malignant neoplasms was noted, but this is a small percentage of all known cases.

Contraindications

There are a number of contraindications, in which the use of the drug "Sandimmun" is categorically prohibited. The instruction necessarily gives a complete list of them. These are malignant tumors, hypersensitivity to the components that make up this medication, hypertension, severe infectious diseases, hyperuricemia, various disorders in kidney and liver function, hyperkalemia, breast-feeding and pregnancy.

Overdose with the drug "Sandimmun"

An overdose of this drug may occur. The signs that testify to this will be the presence of drowsiness, tachycardia, there may be vomiting and headaches, as well as severe kidney failure. When revealing the first signs of an overdose, it is necessary to start washing the stomach and stimulate the appearance of vomiting in the patient, all this should be done immediately after taking the drug or during the first few hours. With the onset of more complex consequences, all vital functions of the body are supported, while dialysis and hemoperfusion with activated charcoal do not bring results and are ineffective.

Keep capsules at a temperature that does not exceed 25 ° C, the solution - up to 30 ° C, but the bottle must be unopened. Keep in places where the child can not reach. Shelf life "Sandimmun" 3 years, and take the drug after its termination is strictly prohibited!