Fibroblasts are what? Cellular rejuvenation by fibroblasts

In recent decades, in the field of professional cosmetology, the technique of correction of the skin by means of restorative biological technologies is gaining popularity. To such, in particular, relates rejuvenation with the injection of autologous fibroblasts.

Scientific validity

This technique has a serious biological basis and is based on the natural ability of the body to regenerate. Fibroblasts are the fibrous cells that are found in every human body. Their goal is the constant production of valuable substances, on which the healthy state of the human body directly depends.

First of all, these cells synthesize the structural components of proteins, as well as connective fibers and hyaluronic acid. The presence of these elements in the tissues in the required quantity and in the correct proportions ensures the stability of the hydrostatic pressure in the cells and gives them elasticity. During life as the person approaches the mature age, the percentage of fibroblasts in the skin covers decreases. They lose their elasticity and under the influence of gravity become flabby and saggy.

At the end of the 20th century, cellular rejuvenation with fibroblasts was included in the number of techniques of classical surgery. The responses of the first patients to whom this technique was applied showed that 100% of injections were administered without any negative consequences.

Sequencing

Collection of tissues for the preparation of the solution is performed under local anesthesia. Samples are sent to the laboratory, from where within several weeks the clinic receives the ready-made materials necessary to perform the rejuvenation with fibroblasts. How the procedure works, you can see in the photo below.

Skin covers of the face, as well as the neck, décolletage and hands are subjected to extensive injection. Shortly before the start of therapy, the areas indicated by the doctor are carefully treated with an anesthetic cream. The drug is injected with special thin needles. Once in the layers of the dermis, active cells begin to produce the most important proteins for the body (collagen and elastin), as well as hyaluronic acid and other elements that are an integral part of the matrix.

The remainder of unused fibroblasts for injection remains at the cryobank at the request of the patient, where they are stored indefinitely at a temperature low in liquid nitrogen. They can be obtained at any time for repeated procedures.

Cellular rejuvenation by fibroblasts: the essence of the procedure

Renewal of connecting regenerating cells not only speeds up the recovery processes in the structure of the skin, but also allows them to be corrected. Along with the folds, shallow scars and other aesthetic defects disappear.

Rejuvenation by fibroblasts is a complex of medical procedures, aligned with the individual characteristics of the patient and referred to as SPRS-therapy. It is carried out strictly in clinical conditions.

For the injection, the surgeon takes samples of the patient's skin and labically makes many copies of its structural elements. Because fibroblasts are their own, not alien cells, the procedure for their implantation is absolutely natural. In the body, natural regenerative processes are triggered, which after a while becomes noticeable visually.

The procedure of injection is painful no more than any of the so-called "beauty injections" and does not leave behind any visible traces, other than positive ones.

The course of rejuvenation

Most often, the introduction of the necessary amount of fibroblasts is carried out for two short-term procedures. They are held for 12 weeks at regular intervals. However, this schedule may vary, because SPRS-therapy assumes an individual approach, depending on the particular features of the skin of the patient.

The result of the procedure is often obvious after the first session, which indicates the amazing speed with which fibroblasts rejuvenate. The photo below shows the effect of the ongoing recovery processes.

SPRS-therapy does not give side effects in the form of allergic reactions. Since fibroblasts are the main element of mesenchymal stem cells, the likelihood of their being rejected by the body is excluded. Courses of therapy are perfectly combined with almost all other methods that exist in cosmetology at the present time.

Indications for the procedure

The introduction of cloned regenerated cells is shown to people at the age of 40 years. However, this technique can be used at earlier stages. In addition, it is worth remembering that the skin is saturated with fibroblasts and is designed to correct minor scarring or defects.

The technology of introducing reductive cells is recommended to people:

• With pronounced signs of aging;
• Middle-aged (for the prevention of wilting of the skin);
• With various kinds of defecates (scars, pockmarks, burns, etc.);
• Wishing to begin formation of fibroblasts with the purpose of improvement and preservation of a tonus.

Patients who testify to rehabilitation measures after cosmetic procedures (peeling, grinding, plastic surgery), also can be shown rejuvenation by fibroblasts. Feedback about this procedure suggests that collection of samples for cell reproduction is best performed at a younger age, when their ability to regenerate is highest.

The principle of the action of embedded cells

Morphological studies of the dermis, artificially saturated with fibroblasts, indicate the extraordinary productivity of such technologies. Soon after the injection, newly found cells are fixed in small groups. This is due to the dosed introduction of biological material, which is characterized by weak diffuse properties.

Inside the intercellular fine-grained substance, synthesized collagen fibers begin to be observed , which is a direct consequence of active regenerative work. Characteristic signs persist for up to 18 months, after which the fibroblasts are fully integrated into the skin structure and become no more active than all its components.

After the expiration of these processes, the active cells can be introduced again according to an individually selected scheme. As a rule, the effect of the repeated procedure is distinguished by a more striking result, since the reductive processes in the skin are already started.

Advantages of regenerative biotechnologies

Embedded in the skin, fibroblasts retain their activity for at least one and a half years. The necessary proteins are produced in the dermis, resulting in a natural cell renewal. The intensity of the rejuvenating effect during the entire duration of the action is parabolic, increasing, and then smoothly coming to naught. By the end of the period, the activity of the inserted cells begins to correspond to the actual age of the patient.

Signs of correction of age and other changes are the following list:

• Significantly reduced the number of folds and the depth of old scars;
• The skin tone is leveled, its elasticity returns;
• The reducing ability of the cells is clearly enhanced;
• Manifested pronounced rejuvenation.

Fibroblasts are cells responsible for the freshness of the skin and, ultimately, for the beauty of a person. Composing a number of other elements of the skeleton of the dermis, they produce and organize a variety of components, maintaining its necessary physiological state.

Contraindications and recommendations

Procedures for the introduction of new cells are not recommended for the following pathological conditions:

• Active stage of infectious disease;
• Presence of malignant tumors;
• Dysfunction of the immune system;
• Rashes and other defects not associated with the effect of infection.

In addition, this therapy is contraindicated in pregnancy and breastfeeding.

Injections of fibroblasts are a rather productive base for other procedures, the purpose of which is to restore the microstructure of the skin and correct its defects. The extensive practice of applying biological rejuvenation technologies shows that the effect of each cosmetic remedy imposed on the SPRS therapy procedure is significantly enhanced.

So, similar procedures are recommended to be combined with a lifting by means of ultrasounds and laser technique of rejuvenation. Also, more obvious results after the administration of fibroblasts are provided by mesotherapy and other techniques.