"Buserelin-depot": reviews of endometriosis. Instructions for use, side effects

In recent years, more and more representatives of the weaker sex who are in reproductive age, suffer from endometriosis. This is a very unpleasant hormonal disease, which requires a comprehensive correction. Often an antitumor drug is used to eliminate it. However, the greatest effect will be achieved with additional surgical intervention.

This article will tell you about the medicine "Buserelin Depot." Reviews for endometriosis about it is different. The opinions of some patients will be described later. Also, you will find out what doctors think about this medicine. It should be said that it informs the consumer about the composition of "Buserelin-Depot" instruction.

In what form is the medicine produced?

About the drug "Buserelin-Depot" instruction says that the drug has two main types - a spray for nasal use and lyophilizate for intramuscular injection. In this case, the second type of medication must be diluted before use. The method of application is always described in detail in the instructions that accompany the medication.

The active substance of the drug is Buserelina acetate. Depending on the form of release in the preparation, there may be additional components.

What is the price of the drug "Buserelin Depo"? The cost of the medicine also varies depending on the type of drug. Nasal spray will cost you 800-900 rubles for a bottle of 17 ml. If you need to buy an injection of medicine "Buserelin Depot", the price of one ampoule with the device for administration will be about 4000 rubles.

What is this medicine? Description of the medicament

The antitumor drug "Buserelin Depot" is a gonadotropin-releasing hormone. It is abbreviated as GnRH. Also from doctors you can hear the designation of gonadorelin and others. To somewhat clarify the situation, it is worth saying that this class of hormones is stimulating. Gonads are testes. In other words, the spray or injection "Buserelin Depot" affects the sex hormones.

The drug actively stimulates the front dose of the pituitary gland. Under its action, the production of two basic substances - follicle-stimulating and luteinizing hormones - is cut off. Without these components, the woman completely blocks ovulation. When treated with the described agent there is a decrease in plasma estradiol to post-menopausal values.

Indications for use of the drug: as instructed

About the drug "Buserelin Depot" instructions for use says that this compound is prescribed if a woman has an excess of estrogens in the body. Often this hormonal disorder leads to the development of endometriosis and the formation of uterine fibroids. Also, the drug is sometimes used among the stronger sex. About the drug "Buserelin Depot" instructions for use says that the drug is strictly prohibited to use it yourself. Appoint a drug and choose an individual scheme of use should a specialist. Otherwise, very unpleasant consequences of improper treatment can develop. The annotation indicates the following conditions when it is necessary to apply the described medication:

• Benign ovarian tumors (follicular and luteal cysts);
• Endometriosis and endometriomas;
• Myoma of the uterus of different sizes and species;
• Hyperplastic transformation of the endometrium;
• Preparation for surgery for fibroids and endometriosis;
• Prostate cancer or suspected of it;
• Infertility treatment and so on.

The medication is often combined with other methods of treatment (laparoscopy, laparotomy, hysteroscopy, mobilization of arteries in the uterus and so on).

What are the contraindications to the use of the drug?

Treatment "Buserelinom-depot" is possible only after a thorough examination and diagnosis of blood at the level of hormones. Also, a woman is recommended to perform an ultrasound examination of the pelvic organs. In some situations, additional research manipulations are indicated.

The composition is strictly prohibited for use in pregnancy and breastfeeding. It is known that this drug is able to penetrate into breast milk. Consequently, the medicine will affect not only the woman, but also her baby. The drug is contraindicated in the period of bearing the child due to teratogenic effect on the fetus. Such a correction can lead to an abortion or delay in the development of the embryo.

The drug is prohibited for use in girls who have not reached puberty. The use of medication can adversely affect their future hormonal background. It is also not advisable to prescribe the composition of women during menopause. After all, these representatives of the weaker sex do not develop the hormones mentioned above.

With increased sensitivity to the components, the drug is not used. The composition with extreme caution should be used during the period of depression, with diabetes. Also, hypertension can worsen after such treatment.

Method of nasal spray application: dosage and scheme

What do they say about the tool "Buserelin-Depot" reviews? With endometriosis, it is very convenient to use a spray. Women who are afraid of injections and want to save money, choose this option. Consumers note that the described drug costs several times cheaper than ampoules for intramuscular injection.

To treat endometriosis, 900 μg of medication per day is prescribed. This portion should be divided into three doses. One spray contains 150 μg of medicament. Proceeding from this, we can draw the following conclusion. The medicine is injected one spray into each nasal passage three times a day.

Consumers report that before using the medication it is necessary to clean the nose. To do this, you can use any convenient means (shower, spray, rinsing). The use of the described substance during rhinitis is allowed. The duration of therapy is up to 6 months.

The disadvantage of this form of release is that it must be taken after a certain time without any deviations from the rules. So, between each injection of the drug should pass from 6 to 8 hours. Doctors advise using the spray in advance to think about the mode of its application and adhere to it.

Injection: the way the drug is used in ampoules

"Buserelin Depot" application can have in the form of injections. In this case, the injection is done exclusively by intramuscular injection. Other drug administration is unacceptable. Before use, the composition must be prepared. Detailed instructions are attached to each ampoule. However, in order to receive competent treatment, it is worthwhile to consult a doctor and already in the hospital to make a medication.

Prepare the suspension with a special solvent. In this case, it is introduced with a needle with a red or pink pavilion. After mixing the substances you need to shake them well and wait a while to get a uniform liquid. Next, draw the composition into the syringe. The peculiarity of this manipulation is that you do not need to turn the ampoule. The syringe after filling is removed from the red needle and inserted into the green one. Air bubbles are released, and an immediate injection is made. It is preferable to use the gluteus muscle for the injection. Pre-wipe the skin with an alcoholic napkin. In extreme cases, it is allowed to inject the medicine into the leg muscle. However, there must be appropriate evidence.

The duration of therapy is from 3 to 6 months. If necessary, it can be longer. The injection is put once every 4 weeks. Women say that it is much more convenient than spraying the composition on the nasal mucosa three times a day. However, this correction will be more expensive.

"Buserelin Depot": side effects from treatment. What do women feel?

The described drug is rarely well tolerated. In most cases, it always causes side reactions. The composition may have different effects on each patient. That is why it is not necessary to be equal to your friends who have tolerated such treatment and complained of certain reactions.

Most often after "Buserelina-depot" a woman stops menstruating. In this case, doctors indicate that this is not a side effect, but a favorable effect of treatment. The composition of its work blocks the production of basic sex hormones. As a result, the endometrium simply does not grow, ovulation does not occur, the phases of the cycle do not change. Menstruation is usually absent exactly as long as the treatment lasts.

The action of "Buserelina-depot" is often accompanied by all the symptoms of menopause and menopause. A woman can feel hot flashes, a frequent change of mood, a decrease in libido. Also, representatives of the weaker sex report an exacerbation of the depressive state, an increase in headaches. That is why during the period of treatment the patient needs psychological help.

Less often the drug can cause problems with hearing and vision. Patients note a feeling of pressure on the eyes, noise in the ears, a feeling of discomfort. If previously there were problems with the heart and blood pressure, then they can become aggravated. Some consumers report an allergic reaction to the described agent. It can be expressed by urticaria, itching, anaphylactic shock. In such situations, the drug must necessarily be replaced by any other analogue.

The composition can provoke weight gain, indigestion, deterioration of the hair condition. Nasal administration of the solution sometimes leads to bleeding, dryness and itching in the nose.

"Buserelin-Depot": reviews of endometriosis

Women with this diagnosis often use the described medication as prescribed by the doctor. They note that the cost of the drug is not as high as it seems at first glance. There are analogues in the composition of Buserelin Depot that also treat endometriosis. For example, the drug "Zoladex". However, its cost is much higher. One ampoule will cost you three ampoules "Buserelina Depo."

Many women with advanced stage of the disease suffer infertility. They can not get pregnant because of the unstable hormonal background. Also, the absence of children is due to the presence of a strong adhesion process in the small pelvis. Often, a miraculously occurring pregnancy begins to develop in the abdominal cavity or fallopian tube. The use of the described medicine allows artificial insemination in childless couples. In this case, the woman first during the cycle takes "Buserelin", after which the hyperstimulation of the ovaries. Representatives of the weaker sex say that after pregnancy and prolonged lactation (if there is no menstruation), the disease can retreat completely.

Patients say that when using the drug "Buserelin-Depot" all the symptoms of endometriosis quickly disappear . Stop painful sensations, bloodsucking. After all, a patient with such hormonal disorders does not know at what time to wait for another menses. Breakthrough "chocolate" bleeding is greatly knocked down from the usual rhythm of life. Also, the patients say that Buserelin helped them get rid of the constant pain that always accompanied the sexual intercourse.

Of course, treatment often leads to adverse reactions. Women feel great discomfort, hot flashes, they sometimes get fat. During the period of correction there is a deterioration in well-being. If the patient's goal is the birth of a child, then depression in this regard can be greatly aggravated. The representative of the weaker sex in the period of correction should be sure to enjoy the support of their relatives and friends. Women who underwent similar therapy say it's worth it. However, an integrated approach will be more effective. We will find out what the gynecologists think about this.

What do doctors say about this treatment?

The drug "Buserelin Depo" reviews doctors has the following. Doctors say that the medicine is quite effective. During the treatment, extinction foci of endometriosis disappear. However, once the treatment is completed, the problem can return. That's why gynecologists advise to carry out complex treatment.

If medical therapy is combined with surgical intervention, then very good results can be obtained. Most often, doctors prescribe the described medicine for two months. After this, an operation is performed (often laparoscopy). By that time the foci of endometriosis become much smaller, which means that the treatment will be minimally traumatic. After intervention, hormonal correction continues for 4-8 months. The forecasts of this approach are very good. In most cases, the woman is no longer disturbed by the usual symptoms, since the adhesions and foci of endometriosis are removed, and hormonal treatment does not allow them to form again.

A small summary of the results

You learned about the sex hormone blocker with the trade name "Buserelin-Depot." Reviews for endometriosis drug has a positive and negative. Those women who undergo correction may negatively speak about the drug. After all, they have very strong side effects. Many representatives of the weaker sex can not withstand therapy and halfway leave the treatment. Positive opinions are expressed by those patients who were able to gain strength and complete such a difficult treatment. They began to feel much better, all the disturbing signs left.

Doctors say that the drug "Buserelin Depot" is one of the most effective tools that help cope with endometriosis. The medicine affects the problem from the inside. It blocks the production of estrogens, which also provoke a large number of foci growth. Patience to you in treatment and good health!