Antibiotics of the penicillin series. Brief description of preparations

Antibiotics of the penicillin series have bactericidal properties, low toxicity, a broad spectrum of antimicrobial activity. In addition, these drugs are available and cheap.

Benzylpenicillin sodium salt is included in the category "antibiotics penicillin series." The drug is acid-resistant and is destroyed under the influence of p-lactamases of intestines (enzymes that completely or partially block the activity of antibiotics). The use of medication intravenous, intramuscular, endolumbic. Immediately before the introduction, the drug is dissolved. The drug has a high penetrating ability in relation to the heart mucosa, kidneys, intestinal wall, synovial and pleural fluid. There is a poor passage through the BBB (hemato-encephalic barrier). Duration of the drug from three to four hours. It shows activity mainly in relation to the gram-positive microflora (cocci), causative agents of diphtheria, syphilis, anthrax and others. The drug is shown for pneumonia, purulent-septic infections, abscesses, diphtheria, syphilis, meningitis and other pathologies.

Benzylpenicillin potassium salt has all of the above properties. It differs from the sodium salt by the limited methods of administration (only intramuscularly).

Phenoxymethylpenicillin (ospen, penicillin-Fau) also belongs to the category "antibiotics of the penicillin series." From previous products is characterized by acid resistance. In addition, the drug is characterized by a high continuous concentration in the blood, as well as good absorption. This antibiotic is indicated for infectious diseases in the lung forms, provoked by penicillin-sensitive pathogens.

In the category of antibiotics of the penicillin series is also Bicillin. This prolonged drug is intended only for intramuscular use. The medication is indicated for the prevention of surgical infections, relapses of rheumatism, and also for therapeutic purposes with syphilis, pneumonia and other pathologies.

Antibiotics of the penicillin group also include preparations of a wide range of effects.

One of these medicines is Ampicillin. The drug is acid-fast. Capable of being absorbed into the blood quickly, penetrating into body fluids and tissues, with the exception of cerebrospinal fluid.

Ampiox has a broad spectrum of antimicrobial effects, as well as bactericidal action on the penicillinase producing staphylococcus aureus. This medication is prescribed for purulent-septic and ENT infections, respiratory tract infections, urine and bile ducts, sepsis, abscess, meningitis, peritonitis and other diseases.

A wide range of effects is also possessed by the drug Carbenicillin. The drug is very effective in relation to infections caused by Pseudomonas aeruginosa and gram-negative bacteria, acid-fast. Does not have resistance to p-lactamases (blocking enzymes). The drug is not absorbed into the digestive tract, so its use is only intravenous or intramuscular.

Semi-synthetic penicillin of a wide range of effects is Amoxicillin. The bioavailability of the drug is more than 90%. Amoxicillin tablets can be dissolved, swallowed or chewed.

It should be noted that, as a rule, drugs of the penicillin series are transferred by patients quite well. Possible mild side effects in the form of allergic skin rashes, vomiting, nausea, upset of the chair.

Antibiotics of a wide spectrum of action often suppress not only a microflora pathogenic, but also useful.

Some pathogenic bacteria show resistance to many drugs. Therefore, scientists create more modern antibiotics that affect new strains.