Urdoks: instructions for use. The medicine "Urdoksa": the price, reviews, analogues, recommendations to pregnant women. Which is better: "Urdoksa" or "Ursosan"?

Many, for sure, heard about tablets "Urdoksa." "What are they from?" - a frequently asked question by readers. Many users write that they often take it with them on vacation to "heal" their liver. But at the same time they overlook the fact that it is a medicine produced for the treatment of serious liver diseases. Therefore, it is so important to know in what cases and how to correctly use the drug "Urdoksa." Instructions for use, contraindications, side effects - all can be found in this article.

Composition of the preparation and form of release

The active substance of this drug is ursodeoxycholic acid, which is, in fact, a less aggressive form of bile acid. Initially, this component was included in the composition of medicines shown for the treatment of reflux gastritis and the dissolution of gallstones. Now the substance is included in many drugs intended for the treatment of cholestatic liver diseases. This preparation is made in the form of gelatinous opaque capsules, the contents of which are granulate or white powder. As auxiliary substances here are silicon dioxide colloidal anhydrous, corn starch, magnesium stearate. The capsule shell contains titanium dioxide, propylhydroxybenzoate, methylhydroxybenzoate, gelatin and acetic acid.

pharmachologic effect

This drug is a hepatoprotective drug. It has cholelitholitic, choleretic, hypocholesterolemic and immunomodulating effects. The active substance of the capsule "Urdoksa" is built into the membrane of the structural cells of the liver (hepatocyte), thereby protecting them from the action of bile salts. Also, the drug stimulates the formation and release of bile, contributes to the complete or partial dissolution of gallstones.

Indications for use

"Urdoksa" instruction, price, reviews - everything will be described in this article. In the meantime, read the list of indications for use:

• Biliary reflux gastritis. The disease that occurs due to disruption of the bile excretory system and asynchronous operation of sphincters. The cause of the appearance of the disease can be imagined as follows: the stomach is regularly thrown acidic contents of the duodenum. As a result, under the influence of bile acids, the gastric mucosa begins to break down.

• Destruction of liver cells (primary biliary cirrhosis) in the absence of signs of decompensation. The disease is more common in women. It manifests itself in the form of inflammatory changes in the liver, autoimmune destruction of its and bile ducts. In this case, the secretion of bile is broken. Harmful toxic substances are retained in the liver. As a result, hepatic failure first develops, and later liver cirrhosis also develops.

• Used to dissolve small and medium cholesterol stones in the normal functioning of the gallbladder (unfortunately, in this case it helps infrequently). It is known that 80% of all stones that form in the gallbladder are cholesteric. Any changes occurring in the composition of the bile formed lead to the fact that it begins to poorly "dissolve" harmful elements, for example, cholesterol. As a result, stones are formed in the gallbladder. They can be very tiny (the size of a grain of sand) and very large (the size of a ball for playing ping-pong). There can be several or only one. Most physicians tend to believe that gallstones are formed as a result of regular consumption of too fatty foods.

The drug "Urdoksa": instructions for use

This remedy is used for oral administration. The dosage of the drug depends on the type of disease and body weight of the patient. For the treatment of primary biliary cirrhosis, it should be used as follows:

• If the body weight is from 34 to 50 kg, then take 2 capsules a day. Use them, usually in the morning and in the evening for one thing.
• If the body weight is from 51 to 65 kg, then take 3 capsules a day. Use them three times a day: in the morning, at lunch and in the evening.
• If the body weight is from 66 to 85 kg, then take 4 capsules per day. Use three times a day this way: morning 1, lunch 1 and evening 2 pieces.
• If the body weight from 86 to 110 kg, then take 5 capsules a day. Use three times a day: morning 1, lunch 2, evening 3 pieces.
• If the body weight is more than 110 kg, then take 6 capsules a day. Use three times a day: morning 2, lunch 2 and evening 3 pieces.

To treat biliary reflux gastritis, the agent should be taken as follows: once a day for 250 mg. The attending physician should determine the duration of therapy with Urdox. The instruction for its application states that, as a rule, it is from 10-14 days to six months. In some cases, the drug "Urdoksa" take more than a year.

In order to dissolve bile cholesterol stones, the agent is usually taken at 250-500 mg per day, which corresponds to 1-2 capsules. The drug is used either after eating, or during it. The full course of treatment is from 4-6 months to a year or more. Supportive therapy is carried out at a daily dose of 250 mg.

Contraindications and side effects

Not everyone can take the drug "Urdoksa." Instruction for use states that the child's age in this case is a contraindication. The tool also has the following restrictions on use:

• X-ray visualizing gallstones (seen in the picture due to high calcium content in the composition);
• Poorly functioning gallbladder;
• Acute inflammation of the gallbladder, its ducts and intestines;
• Decompensated cirrhosis of the liver (a disease in which the liver is completely scarred and can not do its job);
• Marked violations of the kidneys, liver, pancreas;
• Hypersensitivity to the elements of the drug;
• Pregnancy and the period of breastfeeding.

The side effects of the drug are as follows:

• back pain;
• Abdominal pain;
• diarrhea;
• Calcification of gallstones;
• nausea;
• constipation;
• Increased activity of hepatic transaminases;
• Vomiting;
• Alopecia (alopecia);
• dizziness;
• Allergic reactions (urticaria and so on);
• Exacerbation of psoriasis, which appeared earlier.

Prices for medication

The cost of the drug depends on the number of capsules in the package. So, the price of a pack (50 pieces) in different drugstores varies from 520 to 692 rubles, and 100 pieces - from 980 to 1040 rubles.

Application in pregnancy and lactation

This drug has many limitations in the application. The period of pregnancy and lactation is one of them. It's not a secret to anyone that very many medications can have a negative impact on a future child. Thus there is a risk of development of various defects in the embryo and fetus. Many medicines, along with the breast-feeding mother's milk, enter the baby's body. They can have the most detrimental impact on him. The drug "Urdoksa" during pregnancy and lactation is prohibited for use. This rule should be strictly observed. In any case, all medicines taken by women in this responsible for their period of life should be appointed by their supervising physician.

special instructions

We found out what indications and limitations to use the drug we are considering, and also considered in detail how to take "Urdoksa." Now it remains to mention the special instructions noted in his instructions. So, this medication is not recommended to be used together with medications that increase biliary elimination of cholesterol. These are, as a rule, contraceptive contraceptives, estrogens, some lipid-lowering drugs. Also, the use of alcoholic beverages during treatment is prohibited.

The drug "Urdoksa": analogues

When using any medicine, it may be useful to know the names of medications that have a similar effect. The drug "Urdoksa" has the following analogues:

• "Livedovs";
• "Urso 100";
• "Ursodez";
• "Ursodeoxycholic acid";
• Ursodex;
• "Ursoliv";
• "Ursoron Romparm";
• Ursoror S;
• Ursofalk;
• "Ursosan";
• Exhol;
• "Holudexan".

If you analyze the cost of all these drugs, you can conclude that in the price range somewhere in the middle is the drug "Urdoksa." Customer feedback suggests that in some cases they preferred this tool to its expensive counterparts as more effective.

Urdoksa or Ursosan? What's better?

Why is it important to know if there are analogues in any medicine? The most weighty argument here is the price of the medicine. It's no secret that at the present time doctors in polyclinics often write out very expensive advertised drugs, instead of assigning cheaper analogues. The medicinal product we are considering has a mass of medicines similar in composition and action.

Let's try for an example to compare it with one of its analogues. We will find out what is better: Urdoksa or Ursosan? In both cases, ursodeoxycholic acid acts as an active substance. Its concentration in both preparations is the same and is 250 mg per 1 capsule. The form of release is also the same. Medicines are produced in the form of gelatin capsules. If you compare their cost, you can come to the conclusion that the "Urdoksa" means costs an order of magnitude cheaper than its counterpart. So, its cost is on the average 550-600 rubles for 50-piece packing. And the price of the drug Ursosan is an order of magnitude higher. It averages 750-800 rubles. The difference in value is significant. Therefore, perhaps it makes sense to buy a cheaper analogue of the drug "Ursosan".

The difference in these two medicines is observed only in the list of indications for use. The means of "Ursosan" is somewhat larger. In addition to primary cirrhosis of the liver and biliary reflux gastritis, there are such diseases as primary sclerosing cholangitis, cholelithiasis, viral hepatitis in acute and chronic form, autoimmune hepatitis, various liver damage as a result of toxicosis (including alcoholic and medicinal) , Cystic fibrosis, biliary dyskinesia. And in the instructions to the drug "Ursosan" it is said that it can be used for treatment by pregnant women, if only the expected benefit for the mother exceeds the possible risk of complications in the fetus. While the drug "Urdoksa" is strictly forbidden this category of women. In any case, do not hesitate to ask your doctor to give advice on whether the drugs prescribed by him have cheaper analogs. It is not necessary to solve independently the questions: what is more effective, "Urdoksa" or "Ursosan" - what is better in a specific situation? The competent specialist will dispel all doubts of his patients.

Reviews of doctors

Comments of experts about this drug is not so much. Most of them are reduced to recommendations for consumers not to make themselves diagnoses and do not prescribe medicines themselves. This can only be done by a competent doctor in this matter. Also, experts warn that it is not necessary to purchase cheaper analogs of medicines without consulting doctors. After all, this is fraught with consequences. The fact is that, despite the similarity in the composition and principle of action, there are medicines that are supplemented by various components that mitigate their side effects. Determine what means will suit the patient in a particular situation, only a doctor can.

Patient Reviews

On the forums there is a lot of information about where people write that the attending physician prescribed the medicine of "Urdoks" to them. Their feedback on this tool is very different. Someone writes that it perfectly helps and does not cause any unpleasant moments. But there are a lot of comments, where people complain about the manifestation of side effects of this medication. So, for example, one of the most frequently heard complaints from consumers is an exacerbation of the existing psoriasis, nausea, diarrhea and flatulence. The last of this list, according to gastroenterologists, is most likely associated with the emergence of dysbiosis in the process of treatment. It's easy to correct the situation here.

Nowadays in pharmacies there are many different effective drugs that can eliminate dysbacteriosis. All these side effects are present in the list of side effects. Therefore, their occurrence is not sudden. If they do not pass within a few days after the beginning of taking the drug, experts recommend that they cancel it, replacing it with another medicine, which will be prescribed by the attending physician. There are people who claim that this remedy has helped them to completely get rid of gallstones. The results of treatment were confirmed by the results of ultrasound of the bile ducts. In addition, many patients noted improvement in well-being at the second week of use. They noted that bitterness in the mouth disappeared, pains under the ribs on the right passed. However, there are also such consumers who are sure that this drug is too ineffective in this respect. Some users write that they often take it on vacation to protect their liver from unfavorable external factors. They say that on vacation they indulge in excesses in the form of hot drinks and high-calorie food. And "Urdoksa" simply "rescues" them, protecting their liver from overloads. Here it is worth recalling only that this drug has some contraindications and special instructions. Only a doctor can take them into account. Therefore, without his advice to take the medication "Urdoksa" is unreasonable.

We examined one of the drugs for the treatment of certain liver diseases and found out that the population is widely known and in demand.