"Trental 400" - a drug that improves microcirculation

Speaking about the medicine "Trental 400", we will consider it in coated tablets of sustained release. As can be seen from the title of the article, the effect of this drug is aimed at improving microcirculation. By inhibiting the aggregation of erythrocytes and platelets, Trental increases fibrinolysis. Thus, the viscosity of the blood decreases, and its rheological properties are improved.

Expressed in a simple way, we can say that this medicine "liquefies the blood." It is these that are about the preparation "Trental 400" reviews. People write that they used this medicine for blood clots, and it helped them, it helps well for blood vessels.

Let's see what are the indications for the prescription of the medicinal product "Trental 400". Instruction for use informs that this medicine acts on large blood vessels and capillaries, improving their condition and regulating tissue nutrition. The viscosity of blood not only decreases, but the quality of its chemical composition also increases. The vessels expand somewhat.

"Trental 400" improves the metabolic energy processes occurring in the brain, has a beneficial effect on the central nervous system, the blood supply of the extremities. Accordingly, the drug is used in cases where peripheral circulation is impaired. Indications for use are:

• Phlebeurysm.
• Trophic tissue disorders.
• Gangrene, frostbite of the extremities.
• Disturbance of blood circulation in the brain, choroid of the eye.
• Otosclerosis.
• Impotence and others.

The dosage of "Trental 400" is set individually. The average dose is 400 mg, and the maximum daily dose is 1200 mg. Tablets are taken without chewing with sufficient water. If patients have kidney pathologies, the dose of the drug is reduced. Individually, a dosage is selected for the treatment of patients with liver pathologies.

Side effects when using Trental 400 :

• Decreased appetite, dry mouth, exacerbation of cholecystitis.
• Headaches, anxiety, insomnia, cramps.
• Hyperemia of the skin, itching, urticaria.
• Gastric bleeding.
• Reduced blood pressure, arrhythmia, tachycardia and others.

Contraindications to the prescription of the drug, above all, is hypersensitivity to the active substance pentoxifylline, as well as pregnancy, myocardial infarction, strokes, bleeding.

Special instructions : In renal pathologies, the dose of the drug should also be reduced. In addition, such patients should be closely monitored. Severe heart rhythm disturbances, arterial hypotension, hepatic pathology in patients are also indications for careful monitoring in therapy with the use of Trental.

Returning to the reviews, it must be said that some patients complained of headaches, and symptoms of an overdose of this drug are:

• Dizziness.
• Strong headache.
• Chills.
• Convulsions.
• Tachycardia.

It is not difficult to see that the signs of an overdose with this medicine are similar to the side effects described in the manual. In the reviews, you can also see complaints of nausea, irritability and drowsiness, pain in the stomach.

All this suggests that such medicines should be prescribed by a doctor and released on prescription. It is not recommended to apply Trental and Theophylline together, because, thus, the side effects of the latter can be provoked.

In case of overdose, symptomatic therapy may be prescribed. The injured person should be laid on a flat surface in such a way that his legs are elevated. Vital functions of the body are monitored with supporting activities. When there are seizures, they designate "Diazepam".