Lokren: user's manual

The drug "Lokren" pharmacological group beta-blockers with the active substance betaxolol is available in coated tablets.

If you were prescribed a drug "Lokren", the instruction for use contains the necessary information and provides a list of indications: the drug is used for arterial hypertension, angina pectoris, akathisia caused by neuroparalytic drugs.

The drug "Lokren" is contraindicated in case of hypersensitivity to betaxolol or auxiliary substances included, sinus bradycardia (<50 beats per minute), weakness syndrome of the sinus node, arterial hypotension, cardiogenic shock, severe heart failure, severe obstructive respiratory failure and bronchial asthma, with artioventrikulyarnoy blockade of 2-3 degrees, severe Raynaud's disease, peripheral arterial occlusive diseases, in pheochromocytoma, anaphylactic reactions, metabolic acidosis e, cardiomegaly, lactose intolerance, glucose-galactose malabsorption.

With caution or in limited doses, Lokren tablets should be taken with chronic obstructive pulmonary disease, unstable angina, a tendency to bradycardia, artioventricular blockade of the 1st degree, violation of peripheral circulation of Raynaud, diabetes mellitus in decompensation, hypoglycemia, psoriasis, impaired renal and hepatic function , Hyperthyroidism, muscle weakness, in the elderly and childhood, as well as in the conduct of desensitizing therapy.

For the drug "Lokren" instructions for use indicate the initial daily dose, which is equal to half the tablet (20 mg) inwards, which should not be chewed with water without gases and various dyes.

The drug "Lokren", instructions for use during pregnancy, as well as during lactation:

The teratogenic effect of Lokren's drug in animal experiments was not revealed. At the moment there were no cases of teratogenic effect. Prospective controlled studies of congenital malformations have not been identified. Beta-adrenoblockers have properties that reduce blood flow in the placenta, and therefore can affect the fetal development of the fetus. Thus, the drug should be used during pregnancy only as a last resort, when the therapeutic benefit for a pregnant woman exceeds the possible harm to the fetus.

Beta-adrenoblockers and betaxolol, including penetrate into breast milk, because during the lactation drug should not be used, or at the time of its adoption, it is necessary to stop breastfeeding. In any case, it is necessary to consult a doctor.

The drug "Lokren", instructions for use when interacting with other drugs:

The drug is contraindicated with simultaneous use with floktaphenin and sultopride. It is not recommended to take it in combination with amiodarone, with drugs that block "slow" calcium channels - depridyl, diltiazem, verapamil, as well as cardiac glycosides, MAO inhibitors, contrast and iodine-containing drugs.

The drug "Lokren" has such side effects as reactions from the nervous (weakness, hallucinations, dizziness, tremor), cardiovascular (palpitation, sinus bradycardia, Raynaud's syndrome), digestive (nausea, diarrhea, vomiting), respiratory (nasal congestion , Bronchospasm) systems, as well as from the sense organs (visual impairment) and skin (psoriasis-like reactions, increased sweating). There may be allergic reactions. These include weakness, fatigue, headache, drowsiness or vice versa, insomnia. There are also nightmares, anxiety, depression, partial memory loss, hallucinations, tremors.