The drug "Efferalgan" (candles) is an effective analgesic and antipyretic agent

"Efferalgan" (candles) are a medicinal product that has an anesthetic, as well as an antipyretic effect. The active ingredient in this preparation is paracetamol, which refers to non-steroidal agents. The medicine "Efferalgan 150" exerts its effect due to the fact that non-selective inhibition of the activity of the enzyme cyclooxygenase occurs, therefore, the synthesis of prostaglandins from arachidonic acid decreases. As the amount of prostaglandins decreases, the pain impulses decrease in the CNS. And the antipyretic effect that "Efferalgan" candles exert is achieved due to the fact that paracetamol affects the center of thermoregulation in the hypothalamus.

This drug is available in the form of tablets and syrups, and in the form of candles. It is quickly absorbed by the body and its effect is already 20 minutes after ingestion. The maximum concentration of paracetamol in the blood is reached after 30-55 minutes after the "Efferalgan" candles were introduced. This drug is metabolized in the liver, with the formation of pharmacologically inactive metabolites. From the body, metabolites are excreted by the kidneys. The average half-life of the drug "Efferalgan" (suppositories of 150 mg) is excreted after 2 hours, and after a day up to 90% of all paracetamol is taken out.

Recommendations for the use of the drug "Efferalgan"

Candles are designed to treat children aged 3-5 months, whose weight is from 6 kilograms in such cases:

• If the child has a high fever, which is caused by acute respiratory infections, influenza or any other infectious and inflammatory diseases;
• As an anesthetic, if there is a pain syndrome of moderate or weak intensity, it can occur with pain in trauma, muscle pain, burns, headache, as well as toothache, neuralgia.

The drug "Efferalgan" (suppositories) is the method of application and recommended doses

Candles are injected rectally. To do this, you need to get a candle out of the package and gently put the child in the anus, before that you should either cleanse the enema, or wait for the spontaneous emptying of the intestine.

A single dose of this drug depends on the weight of the child and should be 10-15 mg / kg, "Efferalgan" candles are administered 3 to 4 times a day. During the day, you can not take more than 60 mg / kg of this drug.

For children aged 3-5 months, one candle (80 mg) should be used, from 6 months to 3 years - 1 suppository of 150 mg, from 5 to 10 years - 1 suppository for 300 mg of the drug. The interval between administrations should be between 4 and 6 hours.

Usually treatment lasts up to 3 days if the drug is used to lower the temperature, and up to 5 days, if it is used as an analgesic. If there is a need to use this drug for a longer period, you should closely monitor the liver and monitor the condition of peripheral blood.

Also, this agent can be used as a syrup or soluble tablets. Duration of treatment is prescribed by the doctor, however, care must be taken to ensure that the daily dose of paracetamol does not exceed the age norm (regardless of the form in which it is taken).

Possible side effects of the drug Efferalgan

Usually problems after taking this drug does not arise. In rare cases, nausea and vomiting, as well as arterial hypotension, skin allergic reactions, dizziness and increased fatigue may occur.

Contraindications for use

You can not take this remedy to people who have severe liver and kidney disease, as well as those who do not tolerate fructose and chronic alcoholics. If a child is less than 2 years old or weighs less than 13 kilograms, effervescent tablets are also not recommended. The drug "Efferalgan" (suppositories) is not used in people who have recently suffered inflammation (or bleeding) of the rectum. In this case, it is better to choose another form of this medicine.