The drug "Bidop": indications for use, analogues and reviews

The increased pressure brings not only tangible discomfort to the patient, but also is life-threatening. To normalize their condition, very many people resort to folk remedies. However, experts point out that it is much easier to increase the low blood pressure in the home, rather than to lower the elevated blood pressure. Therefore, they recommend using drugs specifically designed for these purposes.

One of the most popular and effective means of hypertension is a medication, such as "Bidop". Indications for use, analogues and consumer feedback on this drug will be discussed further. Also, you will learn how to properly use this medicine, whether it has side effects and contraindications.

Description, formulation, packaging and composition of the medicine

The drug "Bidop", analogues of which are sold in all pharmacies, is available in the form of light brown tablets with yellowish patches and film membrane. They have a round, biconcave form marked "B1" above the risk and the number "5" ("10") under it.

The active ingredient of this drug is bisoprolol hemifumarate. As for the auxiliary components, lactose monohydrate, magnesium stearate, microcrystalline cellulose, crospovidone and yellow pigment PB 22812 (13% iron oxide yellow and 87% lactose monohydrate) are used as auxiliary components.

To buy tablets "Bidop", the use of which is mandatory for people with high blood pressure, it is possible in blisters and packs of cardboard, respectively.

Pharmacodynamic parameters of the drug

What is the medicine "Bidop"? Indications for the use of this remedy are due to its pharmacological action. This drug is a selective β1-adrenoblocker. It does not have sympathomimetic effects, nor does it have a membrane-stabilizing effect.

The drug in question can reduce the activity of renin, reduce the need for myocardium in oxygen and reduce its contractility.

"Bidop" - a drug that has antianginal, antiarrhythmic and hypotensive properties. By suppressing myocardial β1-adrenergic receptors (in small doses), it reduces the intracellular transport of calcium ions, reduces the synthesis of cAMP from ATP (stimulated by catecholamines), has negative chrono, batmo-, dromo- and inotropic effects, and also slows down conduction and excitability.

When the therapeutic dosages are exceeded, the drug shows a β2-adrenergic blocking effect.

At the very beginning of therapy (in the early days), the peripheral resistance of the vascular walls is enhanced. After 3 days it becomes close to the original, but after a prolonged treatment it decreases markedly.

Properties of the medicinal product

What properties are inherent in the medicine "Bidop"? The pharmacological effect of this drug is due to its composition.

The hypotensive effect of the drug is associated with a decrease in the minute volume of blood, sympathetic stimulation of the peripheral-type vascular walls, as well as the weakening of the activity of the renin-angiotensin system, the effect on the nervous system, and the feedback recovery that comes in response to the decrease in pressure.

With hypertension, the therapeutic effect of the drug develops within five days. His confident action comes two months later.

What causes the antianginal effect of this medication? Description of the drug "Bidop" informs that such an action is caused by a decrease in the needs of myocardial tissue in oxygen. This is due to a decrease in heart rate, reduced contractility, lengthening diastole and improving blood supply. Due to the increase in diastolic pressure in the ventricles and the stretching of their muscle tissues, the need for oxygen can increase.

With regard to the antiarrhythmic properties of the drug in question, it is due to the elimination of factors that cause arrhythmia (activation of the sympathetic system, tachycardia, arterial hypertension, an increase in the concentration of cAMP). Also, this drug inhibits AV-conductivity and reduces the rate of excitation of pacemakers.

What other features are inherent in the medicine "Bidop"? Instruction for use, description, reviews of experts say that when taking medicated therapeutic dosages, this drug, in contrast to indiscriminate β-blockers, much less significantly affects the organs that have β2-adrenergic receptors (pancreas, skeletal muscles, musculature of peripheral arteries , Uterus and bronchi), as well as the exchange of carbohydrates. Moreover, the drug in question does not retain sodium ions, and the strength of its atherogenic action is comparable to propranolol.

Kinetic parameters of the preparation

What are the kinetic properties of Bidop? Feedback from patients will not give an answer to this question. It is contained only in the instructions. According to her, after taking the medication, he is absorbed from the digestive tract by 80-90%. The use of food does not affect the process in any way.

The maximum concentration of the active component in the blood is fixed after 2-3 hours. This drug comes into contact with plasma proteins by 30-32%. It passes rather badly through the blood-brain barrier and the placenta.

About 50% of the drug is transformed into the liver. In this case, almost inactive metabolites are formed.

The half-life of the drug reaches 12 hours. Approximately 2% of the drug is excreted together with bile and about 98% - by the kidneys.

Indications for use

"Bidop" is not only an antihypertensive drug, but also an anti-anginal and anti-arrhythmic remedy. Thus, it is prescribed for elimination of arterial hypertension and for preventing attacks of exacerbation of stable angina.

Contraindications for an antihypertensive drug

Now you know why you need a medicine like Bidop. Indications for use were presented above. However, the drug in question is categorically prohibited from prescribing for:

• Shock;
• Collapse;
• Acute heart failure;
• Pulmonary edema;
• Sinoatrial blockade ;
• AV blockade of the second or third degree (without an electrostimulator);
• Syndrome of weakness of the sinus node;
• Severe bradycardia;
• Chronic decompensated heart failure, which requires inotropic therapy;
• Raynaud's disease ;
• Arterial hypotension;
• Metabolic acidosis ;
• Simultaneous administration of MAO inhibitors (except MAO B-type);
• Cardiomegaly (without heart failure);
• Bronchial asthma and severe COPD;
• Changes in peripheral circulation, especially in later stages;
• Pheochromocytoma (without taking alpha-blockers);
• Sensitization to drug substances or other beta-blockers;
• Intolerance to lactose, malabsorption of galactose / glucose and a lack of lactase;
• At a minor age.

Careful appointment

Indications for the use of "Bidop" are listed in the attached instructions. It also says that with special care this drug is prescribed for diabetes mellitus, renal or hepatic insufficiency of chronic type, myasthenia gravis, psoriasis, thyrotoxicosis, AV blockade of the first degree, Prinzmetal angina, depression, allergy in history, strict diet and elderly persons Age.

Method of taking and dosage of medicament

What is the purpose of the appointment and how to use the drug "Bidop"? Indications for use, the instructions for this medication are presented in this article.

Take oral tablets preferably in the morning, on an empty stomach. They can not be chewed, otherwise you will damage the film shell.

The dosage of this product is selected individually. To do this, you should always contact the doctor.

So how should you take the medicine "Bidop"? Indications for use, or rather - their availability - this is an important condition for the appointment of this medication.

In order to prevent acute attacks of stable angina and in the presence of arterial hypertension, patients are given an initial dose of 5 mg. It is taken every day, once.

If required, this amount is increased to 10 mg. In this case, the reception multiplicity is retained.

The maximum daily dosage of the medicine "Bidop" is 20 mg.

In people with impaired renal function, as well as severe liver diseases, the highest dosage is 10 mg per day.

Correct the specified amount of medication to older persons is not required.

Undesirable effects

What side effects can the "Bidop" medication cause? Patients' opinions indicate the possible occurrence of certain undesirable effects. It:

• Dry eyes, impaired vision, decreased salivation, conjunctivitis.
• Orthostatic hypotension, AV blockade, severe depression of pressure, decreased myocardial contractility, sinus bradycardia, impaired myocardial tissue conductivity, arrhythmia, symptoms of cardiac insufficiency (chronic), angiospasm, chest pain.
• Asthenia, weakness, fatigue, sleep disorders, confusion, myasthenia gravis, dizziness, nightmarish dreams, paresthesia in the extremities, depression, anxiety, headaches, tremors, hallucinations, convulsions.
• Nasal congestion, difficulty breathing when taking the drug in high doses or in people with a predisposition to bronchospasm and laryngospasm.
• Nausea, hepatitis, dryness of the oral mucosa, taste distortion, vomiting, liver disorders, constipation, hypertriglyceridemia, abdominal pain, diarrhea, hyperbilirubinemia, increased concentration of liver enzymes.
• Exacerbation of psoriasis, psoriasis-like reactions, skin hyperemia, exanthema, increased sweating, alopecia.
• Hyperglycemia, hypothyroid status, hypoglycemia (in people who use insulin).
• Thrombocytopenia, agranulocytosis, leukopenia.
• Arthralgia, decreased potency, lumbulgia, weakened libido, thoracalgia, withdrawal syndrome.
• Hives, itching, rash.
• Bradycardia, intrauterine growth retardation.

Overdose Symptoms

What side effects are observed when taking higher doses of the Bidop? Indications for the use of this tool are far from the only conditions for its use. It is very important to observe all dosages of the drug, which were recommended by the attending physician. If this advice is disregarded, the patient may experience signs of an overdose such as a bradycardia, ventricular extrasystole, cyanosis of hands, arrhythmia, bronchospasm, AV blockade, dizziness, severe depression of pressure, fainting, chronic heart failure, convulsions, difficulty breathing and Hypoglycemia.

To eliminate such conditions, the patient is washed with a stomach, given enterosorbents and performs symptomatic treatment.

Drug Interactions

Is "Bidop" (drug) compatible with other drugs? What this medicine is used for, we found out. However, in combination with other medicines, it should be administered with extreme caution.

With the intravenous administration of the drug "Phenytoin", as well as with the use of funds for inhalation anesthesia, the cardiodepressive effect of "Bidop" increases.

Radiocontrast iodine-containing drugs for intravenous administration increase the risk of anaphylactic reactions.

"Bidop" often masks signs of developing hypoglycemia. It also increases the concentration of xanthines and lidocaine in the blood.

Sympatholytics, diuretics, "Clonidine", "Nifedipine", "Hydralazine" and other antihypertensive drugs when combined with "Bidop" lead to a strong decrease in pressure.

Tetracyclic and tricyclic antidepressants, as well as ethanol, hypnotics, sedatives and antipsychotics, increase the CNS depression.

Special Recommendations

What should the patient know before taking the Bidop tablets? Reviews of doctors say that at the very beginning of treatment patients should be careful and attentive while driving.

The control of people who take the drug under consideration includes measuring the pulse and pressure characteristics, as well as determining the blood sugar level and conducting an electrocardiogram. Elderly people need to monitor the kidney system.

Before the start of treatment it is necessary to diagnose the function of breathing in patients with a history of pulmonary embolism.

When treating persons with pheochromocytoma, there is a risk of developing paradoxical arterial hypertension.

In people who smoke, the effectiveness of beta-blockers is reduced.

If a planned surgical intervention is required, the medication should be canceled two days before the general anesthesia.

With the development of depression, therapy must be stopped.

It is forbidden to interrupt the treatment abruptly due to an increased risk of myocardial infarction or severe arrhythmias. The medication is canceled gradually, reducing the dose for two weeks or more.

Tablets "Bidop": analogues and cost

If necessary, the preparation in question can be replaced by such means as "Bisocard", "Aritel Kor", "Tirez", "Aritel", "Niperten", "Bidop Kor", "Cordinorm", "Biprol", "Coronal", "Biol "," Corbis "," Bisogamma "," Concor "," Bisoprolol "," Concor Cor, "" Bisomor "," Bisoprolol-OBL "," Bisoprolol-Teva. "

The cost of this antianginal, antiarrhythmic and antihypertensive medication is about 250-300 rubles (28 tablets).

Reviews about the drug

Now you know what can be prescribed from such a medicine as "Bidop". Indications for use, consumer feedback on this medication are presented in the materials of this article.

The reports of patients indicate that the effect of the agent under consideration is very effective. Tablets "Bidop" quickly enough reduce pressure and noticeably weaken all signs of ischemic heart disease.

However, it should be noted that this drug very often causes side effects. They can be manifested by any organs and systems.

It should also be noted that for 20% of people with angina pectoris, this remedy is ineffective. Doctors explain this by the presence of severe coronary atherosclerosis, as well as an increased diastolic volume of the left ventricle.

If there is no effect, the patient should consult a doctor for another therapy.