Trypsin: instructions for use. "Trypsin": reviews

Over the past few years, proteolytic enzymes for enzyme therapy, such as the means "Chymotrypsin" and "Trypsin", have become very popular. Instruction for use reports that these drugs are prescribed for ophthalmic pathologies. For the first time these enzymes were isolated by the American biochemist and professor John Howard in experimental animals. They are produced by the pancreas of cattle and mammals. Activated under the influence of enterokinase and trypsin.

Through multiple studies, scientists came to the conclusion that proteolytic enzymes can be effectively used in ophthalmology (as an antibacterial, anti-inflammatory and decongestant) for the treatment of cataract extraction, uveitis, posttraumatic disorders of the eyelids, central retinal vein thrombosis, lens subluxation, iridocyclitis and purulent lacrimal processes Channels.

It should be noted that an overdose with a different mode of use was not detected. But despite a rather wide range of applications, the release of these medicines was suspended after the collapse of the USSR. Now the production is again established in Ukraine by the Kiev company, which produces bacterial products under the brand name "Biopharma".

How are they produced?

Preparations "Trypsin" and "Chymotrypsin" for today produce in the form of lyophilized crystalline powder of white color, which has no smell. It dissolves easily in saline and ordinary water. In ophthalmic clinics, medicines are used for subconjunctival, intramuscular and intravenous injections.

They are also used in the form of inhalations, dust and baths. Widely used and electrophoresis for the treatment of most diseases. This method of administration gives effective results at low dosages, in contrast to other methods of administration. Scientifically proved that the activity of enzymes even under the influence of current does not decrease.

This technique can successfully treat hemorrhage in the eyeballs, as well as degenerative-dystrophic, adhesive and inflammatory processes. The drug "Trypsin", the instruction for its use recommends its therapeutic use for retinal hemorrhages, is also used for chorioretinitis, retinal degeneration, endophthalmitis and atrophic processes of the optic nerve.

What function in the human body does trypsin do?

The enzyme is involved in the cleavage of peptides and the hydrolysis of proteins into simpler elements. The crystalline substance is produced by our pancreatic system in the form of trypsinogen (inactive state of the enzyme). After it enters the duodenum, trypsin is activated by the enzyme enteropeptidase and bile. About the pathological abnormalities of the gland is indicated by the absence in faeces of this substance. Trypsin in the stool can also not be detected with pancreatic fibrosis.

Increase and decrease in the activity of the enzyme in the blood about what it says?

It is rarely found in patients with malignant formations and viral infections. Serum activity is usually reduced in people with cancer of the gland, chronic pancreatitis, cystic fibrosis and diabetes mellitus. If suspected of these pathologies, the drug "Trypsin" (crystalline) is prescribed.

Pharmacology of medicament

It is an anti-inflammatory drug that helps dilute viscous sputum. It cleaves fibrinous neoplasms and dead tissue. It is proved that the medicine does not exert a destructive effect on hemostasis.

At what diseases is the "Trypsin" medication prescribed?

The instructions for use clearly indicate that this medicine relieves respiratory system diseases: bronchitis, pneumonia, tracheitis, pleural empyema, postoperative lung atelectasis and exudative pleurisy. In addition, the medication is prescribed by doctors for the treatment of periodontitis, osteomyelitis, thrombophlebitis, iridocyclitis, sinusitis and otitis. The drug helps with injuries, bedsores, burns and purulent wounds.

Mode of application

A solution of crystalline trypsin is used in several ways.

In the form of electrophoresis, aerosol, intravenous and intrapleural. The duration of therapy is usually 6 to 15 injections. Before use (for adults), 0.005 g of the substance is dissolved in a sterile solution of sodium chloride (0.9%) or procaine.

With wounds and burns make compresses topically (in the form of a solution of trypsin or powder). Before applying the dressing, 50 mg of the substance is diluted in 5 ml of sodium chloride or sterile water. The wound is treated and then the compress is applied for two days. Periodically, the dressing is moistened with antiseptic, as dry gauze will not give the proper effect. If after 24 days the wound is not tightened, then the procedure is repeated.

In the form of drops: make a drug from 0.2-0.25% solution.

In the form of inhalation: the drug is injected with a bronchoscope or medical inhaler. After the procedure, the mouth is rinsed, and the nasal passages are washed with sterile water.

Side effects

In rare cases, allergic reactions are possible. With the inhalation route of administration, hoarseness, irritation and redness of the mucosa of the respiratory tract can be observed. With intravenous administration, patients will experience hyperemia at the injection site, a slight redness and soreness.

Contraindications

It is forbidden to inject "Trypsin" into the bleeding surface. Instruction for use warns that it is not possible to apply compresses to the expressed area of malignant tumors. Contraindicated remedy for dystrophy and cirrhosis of the liver, pancreatitis, hemorrhagic diathesis and infectious hepatitis. Also not applicable for bronchial asthma, emphysema and acute forms of tuberculosis. People with hypersensitivity should be replaced with another medicine.

Storage conditions

Sold only on prescription. Before buying, be sure to check the expiration date (not more than three years). Keep the medication better in the refrigerator - in the door, or in a dry cool and sheltered from sunlight at a temperature of no higher than +10 ° C. The pricing policy ranges from 400 rubles for ten ampoules.

Medicines of a similar action

These include Pax-trypsin, Terridecase, Ribonuclease, Asperase, Lizoamidase, Dalcex, and Profesim. Only in ampoules a medication "Trypsin" is produced. An ointment based on this substance is called "Irukson".

Conclusion

In medical practice, proteolytic enzymes "Trypsin" and "Chymotrypsin" have proven themselves as highly effective agents in the fight against many pathologies. They are widely used by most ophthalmologic institutions for the treatment of small hemorrhages, schwart and adhesions, since such processes can lead to severe pathologies (before loss of vision) with incorrect therapy.

To date, the use of enzymes in combination with modern antibacterial, antihistamine, antiglaukomnymi and hormonal drugs at times increases the effectiveness of treatment of eye diseases. The description and instructions are presented for informational purposes, it is dangerous for one to prescribe medication independently. We recommend that you consult a therapist for an accurate diagnosis of the disease. He will also find out if you are allergic to this medication.

Patient's opinions

Most people who have tried this medicine on themselves speak about it with delight. For some it made it possible to recover faster and get back on its feet. Excellent helps to cope with joint diseases: removes soreness, relieves inflammation and restores motor function. Many patients are very cured with Trypsin medication.

Reviews in a positive way about this drug are often numerous. Indispensable tool for severe cuts and injuries. After applying the compress, edema, redness decrease and tissue regeneration occurs more quickly. None of the patients expressed discontent.

The doctors themselves and specialists praise the tool and consider it universal and highly effective. With the help of him you can achieve an amazing therapeutic result. Many patients with diseases of the respiratory system were helped precisely by inhalation of the Trypsin solution. For a couple of days, the symptomatic symptoms disappear, a person feels a surge of energy.

Patients taking this medication were satisfied, as well as medical workers who prescribe it for treatment. Proteolytic enzymes show effective results in many areas. Take care of your health and take a course of therapy in a timely manner.