Preparation "Protafan": instructions for use, storage rules, analogues

Diabetes mellitus is a complex and incurable disease that requires constant control over nutrition and daily intake of insulin. Different degrees of ailment may require a different approach to therapy. For example, there is an insulin-dependent and insulin-independent type of pathology. In any case, without treatment, this disease can lead to rapid death of a person.

Due to various drugs the patient can lead a full life long enough. One of them is Protafan. Instructions for use should not only be read by the patient, but learned by heart. This will help to avoid the various side effects that sometimes occur during taking the medicine.

General product description

So, "Protafan", the instruction for the use of which comes with the drug, is an artificially processed single-component human insulin, which is characterized by the duration of the action. It is produced abroad (in Denmark), so its cost can not be small.

Basically prices depend on the dosage and form of the drug. Its cost varies between 350-1800 rubles. In principle, a patient can receive such a drug from an endocrinologist who is registered.

Composition of the means and forms of its production

If you need to purchase "Protafan", the instruction manual will tell you about several of its forms:

- Suspension used for subcutaneous injection, which contains 100 IU / ml of active ingredient and is packaged in 10 ml vials.

- Liquid in cartridges of 3 ml, which contains 100 IU / ml of the main component.

- Blister with syringes in an amount of 5 pcs. Each of them contains 1 dose of medicine.

- A suspension in a bottle that has a lower insulin concentration of 40 IU / ml.

The drug is packed in a cardboard box. It should be noted that the liquid must have a white tint and be cloudy. However, with prolonged storage, it becomes transparent with a white precipitate at the bottom of the vial. Before using the substance, the bottle should be shaken well.

How does the drug work?

The drug "Protafan", the instruction on which application should always be at hand, penetrates well through the membrane inside the cell, where it causes a complex biochemical reaction of protein phosphorylation. It facilitates the penetration of glucose through the cell membrane and its assimilation by the tissues of the body. This drug also enhances the synthesis of peptides and accelerates the production of glycogen.

The doctor can not always prescribe insulin "Protafan". Instructions for use include clear indications for fluid administration. It should be noted that the maximum effect of the action of the main component is observed for 4-12 hours. And it lasts about a day. This is why a patient may need a simultaneous intake of short-term insulin.

What indications for use exist?

"Protafan" (instructions for use, photos and other features of the medicine set forth in the article) can be introduced with such diseases:

1. Type 1 diabetes mellitus.

2. Diabetes mellitus type 2.

In this case, monotherapy or combinations with other insulin preparations can be used. In addition, the product can be used for other purposes. For example, his appointment in veterinary medicine is known. "Protafan" (the instruction for use for dogs provides for its possible replacement with other medicines) is administered to animals in the presence of diabetes.

Contraindications

Among the limitations that completely or partially exclude the possibility of using the drug, you can name such as:

- Insulinoma - a benign tumor, which contributes to uncontrolled production and shipment to the bloodstream of insulin.

- Hypoglycemia - too little level of glucose in the body.

It should be noted that pregnancy and the period of feeding the baby are not contraindications. The drug does not carry a chemical or biological hazard for either the mother or the child.

What side effects can occur?

Like any other medicine, "Protafan NM" (instructions for use can be obtained from a doctor) can give undesirable effects:

- The condition of hypoglycemia, which is characterized by the appearance of cold sweat, fatigue, pallor of the skin, irritability.

- Lipodystrophy - decrease in the volume of adipose tissue under the skin (appears if the injection is done constantly in the same place).

- Allergies: skin rash, redness.

- Disruption of metabolic processes in the body.

Disorder of visual acuity.

- Decreased blood pressure.

- Redness, swelling, or itching at the injection site.

In principle, these consequences are quite probable. However, this does not mean that they will necessarily appear.

Method of administration and dosage

If you are assigned Protafan, the instructions for use (the dose should be determined by the doctor depending on the type and severity of the disease) provides for only subcutaneous administration of the liquid. Naturally, before the injection, the substance must be brought to a homogeneous state.

On average, the daily insulin rate varies between 1.5-1 IU / kg body weight. With an improvement in the state of the body, the dose of the agent may decrease slightly. The initial rate for people who suffer from insulin-dependent type 2 diabetes is 0.3-0.6 IU / kg per day.

The injection is simple enough:

1. First, try to shake the ampoule so that the fluid state becomes homogeneous.

2. In the syringe, collect as much air as you need to collect the substance afterwards, and enter it into the vial.

3. Turn the bottle over and put in the syringe exactly as much fluid as you need for the injection.

4. Remove the needle from the vial and release the remaining air from the syringe.

5. Wipe the injection site with alcohol and inject.

Naturally, during the procedure you need to remember to monitor the correctness of the dosage. In case of excess of the norm, even the brain can be affected. In case of an overdose, the patient should be given a glucose solution or sugar. If the patient is unconscious, then intramuscularly, intravenously or under the skin, he urgently needs to enter glucagon.

Note that you can not use the medicine if it does not become homogeneous. Perhaps, the term of its operation is over.

Interaction and specific instructions for use

What else do I need to know while using Protafan? Instructions for use (analogues you will consider later) tells about some features of combining the drug with other drugs. For example, such substances can provoke a hypoglycemic syndrome: acetylsalicylic acid, "Fenfluramine", amphetamines, tetracyclines, diuretics, contraceptive hormonal drugs, tricyclic antidepressants. That is, with these products you need to be as cautious as possible.

During treatment, one must constantly monitor the level of glucose in the blood. You can inject liquid under the skin of the thigh, abdomen, buttocks. Often an injection is made into the deltoid muscles of the shoulder. It should be borne in mind that the administration of the remedy under the skin of the thigh somewhat slows its absorption. In no case should it be allowed to get a clean solution into the vein.

During insulin therapy, consider the presence of concomitant pathologies, which may cause a need for an increase in the dose of the drug. Transfer to another type of substance should be carried out by a doctor. Attention is drawn to the fact that with the preliminary application of highly purified porcine insulin, the dose of recombined does not change. If a mixed or bovine component was previously used, the "Protafan" norm should be reduced by 10%.

Particular attention should be paid to elderly and senile patients. When prescribing this medication, one should be guided by the paramount task of preventing hypoglycemia and alleviating diabetic symptoms.

Reviews, storage features and analogues of the drug

The main document that patients should study before taking the drug Protafan is the instructions for use. The drug is stored at a temperature of 2-8 degrees. That is, you can put the liquid in the refrigerator. Please note that you can not freeze the product. Used syringes must be disposed of immediately. It is advisable that the bottles with insulin do not get direct sunlight. Shelf life of the product is 2 years.

As for cheaper drugs with the same active ingredient, you can ask the doctor about such medicines:

- "Actrapid NM".

- "Lantus Optiset".

- "Humulin Lente."

- Suspension of human insulin.

As for the reviews, they are mostly positive. Patients noted good product efficiency, improvement in general condition. Naturally, the cost of the drug for most patients is quite high. Today, pharmaceutics provides a huge selection of other drugs that can meet your needs.

That's all the features of the product. Be healthy.