"Estrofan": instructions for use in veterinary medicine, composition and reviews

What is Estrofan? The instructions, the method of application, the composition of the medicament will be indicated below. Also, you will learn about who is prescribed this drug and under what indications.

Form, composition

The drug "Estrofan", the instruction for its use is in a cardboard pack, goes on sale in the form of an injection solution. The active component of this agent is cloprostenol, and auxiliary ones are citric acid, sodium hydroxide, chlorocresol and water for injections.

In appearance, this medication is a clear solution without color and pronounced odor. It is packaged in ampoules of glass or glass bottles, which are plugged with stoppers made of rubber and fixed with aluminum caps.

Pharmacological properties

What features are typical for the drug "Estrofan"? Instructions for use in veterinary medicine states that this drug refers to the pharmacological group of hormones and their antagonists.

Kloprostenol is a hormone prostaglandin PGF2a (synthetic). It is able to have a luteolitic effect on the yellow body of the ovaries, and also to eliminate the inhibitory effect of progesterone on the hypothalamic-pituitary complex and promote the growth of follicles. Due to this effect, the substance in question increases the level of estrogens in the blood, causes sexual hunting and ovulation of ripening follicles. Also, cloprostenol increases uterine contraction.

Kinetics of the agent

What are the kinetic properties of the Estrofan solution? Instructions for use in veterinary medicine states that in the animal body the main substance of this agent is metabolized fairly quickly, after which it is excreted along with the urine within 24 hours.

In terms of its effect on the living organism, the drug "Estrofan" refers to moderately dangerous drugs (3rd class of danger).

Indications for use

Instructions for the use of "Estrofan" (the composition of the drug was mentioned above) states that this remedy causes synchronization and estrus in mares, common and spring cows. It is also used to induce farrowing of sows.

In small and large cattle, this drug treats abnormalities in ovarian function, post-service and postpartal anestrosis (including silent estrus, impaired cycle periodicity, persistent yellow body, anovulation cycle, luteal cyst), as well as endometritis, post-puerperal diseases of the uterus, its festering , Interruption of pathological and normal pregnancy (in the first half).

In what other purposes is the preparation "Estrofan" used? Instruction for use in veterinary medicine reports that this medicine is well manifested in the combination therapy of follicular cysts.

Dosing and Administration

The instruction on the use of the veterinary preparation "Estrofan" states that this means is administered intramuscularly to cattle. To synchronize the estrus, it is prescribed 2 ml twice a day at intervals of ten days.

The first dose of the drug is used in any phase of the cycle. On the eleventh day after the first injection, a double dosage is administered, and on the 14th day artificial insemination is performed followed by a repetition on the fifteenth day.

Before each use of the injection solution for synchronization in a domestic animal, a thorough examination of the genitalia should be performed.

For the treatment of ovarian disorders, the drug in question is administered 2 ml each. In this case, artificial insemination is carried out at the first heat. If it does not occur, then the medicine is used repeatedly in a dosage of 2 ml, on the eleventh day after the first injection, followed by artificial insemination after 72-75 hours.

In order to treat follicular cysts, Estrofan solution is administered once in an amount of 2 ml, not earlier than on the tenth day after the administration of LHRH or HCG and the setting of a positive ovarian response. In this case, the estrus should occur on the third day after the administration of the drug.

Treatment of post-puerperal diseases of the uterus is carried out by administering 2 ml of the drug. If required, this therapy is supplemented with intra-intranetic drug application (by washing or in the form of a foam). In this case, insemination (artificial) is carried out on day 14, and at 15 - it is repeated.

Interruption of pregnancy in domestic animals is treated with the introduction of 2 ml of the drug. Follow-up care depends on their condition.

A one-time dose of the agent in question for the sow is 0.7 ml. In this case, it is introduced from the 111th day of pregnancy. Most often, induced growth occurs 39 hours after the administration of the drug.

Personal prevention measures

Now you know how to use the drug "Estrofan". Instructions for use in veterinary medicine have been described in detail above.

When working with this medication, you should follow all safety rules. After completing the veterinary work, you should thoroughly wash your hands and face.

When the drug is in contact with the visual membranes or the skin, they should immediately be rinsed with plain water. Veterinarians with hypersensitivity to medication substances should avoid direct contact with it.

When developing an allergy or accidental ingestion of the solution, you should immediately consult a doctor.

Empty vials of medicament can not be used for domestic purposes. Such containers must be disposed of.

Reviews

Most reviews of the veterinary preparation "Estrofan" are positive. Farmers argue that after the use of this tool, their livestock has significantly decreased mortality due to internal diseases, and the birth rate of young animals has increased markedly.

As for the deficiencies of this drug, most people refer to it its toxicity to humans. Therefore, to do injections, animals should only be experienced professionals, observing all the requirements of safety and personal hygiene.