HealthPreparations

'Dexamethasone' tablet

"Dexamethasone" tablets are a drug that belongs to the pharmacological group of hormonal drugs. It has many effects, it is used to treat external and internal diseases. However, "Dexamethasone" has many side effects, so it is only prescribed if necessary. Abrupt withdrawal of this drug can also lead to a significant disruption of vital functions, the main of which will be a decrease in the production of hormones in the adrenal cortex.

"Dexamethasone" tablet has a complex mechanism of action, which affects a fairly large number of body processes. The drug directly affects the inflammatory foci, suppressing the main functions of tissue macrophages and leukocytes, reduces the permeability of capillaries, which is due to the reaction of the biologically active substance of histamine. The active substance also reduces the synthesis of leukotrienes, prostaglandins and specific immune antibodies. Depending on the dose can act on metabolic processes of metabolism of fats, carbohydrates, proteins. The drug stimulates the synthesis of glucose, promotes the capture of essential acids by the kidneys and liver. An increase in carbohydrate levels in the blood contributes to the release of pancreatic hormone cells by the insulin hormone. "Dexamethasone" tablets stimulates the processes of lipolysis due to the obstacle to the capture of fat cells by glucose. However, increasing the release of insulin leads to the processes of decay of these substances. The catabolic effect of the drug prevents its long-term use, as a result of which Cushing's syndrome and osteoporosis can develop. Stimulation of the production of pepsin and hydrochloric acid can contribute to the development of peptic ulcers.

Systemic use of the drug causes anti-inflammatory, antiallergic, immunosuppressive, antiproliferative action.

"Dexamethasone" tablets have a lot of indications, which is explained by the multitude of the effects called. Among the diseases that are successfully treated with this drug, Addison-Birmer disease, hypothyroidism, subacute and acute thyroiditis, progressive ophthalmopathy, exacerbation of rheumatoid arthritis, hemolytic anemia, agranulocytosis, malignant tumors, cerebral edema should be noted. The drug has found wide application in reanimatology and traumatology. When the appearance of inflammatory foci after surgery, Dexamethasone is also prescribed. The form of release in this case is a solution.

The drug has a strict dosing regimen, which is individually selected for each patient. Often he is appointed once in the morning, because at this time he optimally affects the state of the body and almost does not cause common disorders.

"Dexamethasone" tablets cause a huge number of side effects that affect virtually all body systems. The most severe of them are insufficiency of the adrenal glands, steroid diabetes, hepatomegaly, myocardial dystrophy, convulsions, corneal perforation, pancreatitis, duodenal ulcer and stomach, pancreatitis.

Contraindications to Dexamethasone are the following: hypersensitivity, systemic mycosis, joint damage of infectious genesis, obesity of the last degrees, diseases of the eyes of viral and infectious nature, trachoma, glaucoma. Pregnancy, lactation are the periods in which "Dexamethasone" can be used. Dosage should be strictly regulated, and constant monitoring of the child's condition is also necessary. If there are dangerous complications, you should reduce the dose until the final cancellation.

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