"Desal": instructions for use, description, release forms, reviews

How should I use Dezal? Instructions for use, indications for the use of this tool will be discussed in this article. Also you will learn about the forms in which you can buy this medication, how it works on the human body and so on.

Forms of release, description of the preparation, its composition and packaging

Among the patients, the most popular are the tablets from the Dezal allergy. Coated with a film sheath, they contain an active substance, such as desloratadine. In addition, the preparation also includes auxiliary elements in the form of magnesium stearate, microcrystalline cellulose, talc, corn pregelatinized corn starch and mannitol.

For sale tablets in packages of cardboard for 10 or 30 pieces.

In addition to the mentioned form of medicine, another type of drug "Desal" is produced. The solution (instruction on the use of the agent will be discussed below) is mistakenly called a syrup. It is transparent, colorless and free from foreign particles. Desloratadine is also the active substance of this form. As for the auxiliary components, they include the flavoring "tutti-frutti", sorbitol, disodium edetate, propylene glycol, sucralose, citric acid monohydrate, hypromellose and sodium citrate dihydrate.

Children's solution "Desal" (syrup) goes on sale in bottles of dark glass (50, 100, 60, 150, 120 or 300 ml). Also included is a measuring spoon (5 or 2.5 ml) or a syringe dispenser (5 ml).

Pharmacological characteristics of the drug

What is the "Dezal" medicine? Instruction for use says that this antihistamine is a long-acting agent . It is a blocker of histamine peripheral H1 receptors. The active substance of the drug is the primary active metabolite of loratadine. Desloratadine inhibits reactions of an allergic nature, and also releases pro-inflammatory cytokines and chemokines.

Due to its pharmacological properties, the drug "Desal" prevents the development of allergic reactions, prevents their flow, has antiexudative and antipruritic effect, prevents the development of edema of the tissues, reduces the permeability of capillaries, prevents spasms of smooth muscles.

One can not help saying that the medicine in question does not have a negative effect on the nervous system, does not have a sedative effect, does not affect the speed of psychomotor reactions and does not cause drowsiness.

The action of the main substance begins 30 minutes after taking and continues throughout the day.

Pharmacokinetics of the drug

How long is the drug "Desal" absorbed? Experts say that after taking the medication inside desloratadine is absorbed quickly enough from the digestive tract. It is determined in the blood in half an hour, and its maximum concentration is reached in about three hours.

The connection with proteins is about 85-89%. Simultaneous intake of water or food does not affect the distribution of desloratadine in any way. It does not penetrate the BBB.

The terminal phase of the half-life is 27 hours. The drug is displayed as a glucuronide compound along with feces and urine.

Indications for use

When do you prescribe the drug "Dezal"? Instructions for use indicate that this medication is used to alleviate, as well as eliminate the following symptoms:

• Urticaria, including itching and rash;
• Allergic rhinitis, including sneezing, nasal congestion, rhinorrhea, itching in the nose, itching of the palate, itching and redness of the eyes, lachrymation.

Contraindications to the use of medicament

This drug can not be administered when:

• Breastfeeding;
• In childhood (patients under 12 years);
• Pregnancy;
• Hypersensitivity to any substances of the drug.

Also it should be noted that with special care the agent in question is prescribed for renal failure (severe).

Medication "Desal": instructions for use

In what dosage do you prescribe the drug "Dezal"? In tableted form, such a drug is taken orally, regardless of food intake. To adolescents, as well as adults, a medication is prescribed for 5 mg or one tablet once a day.

As for the solution, it is also taken inside, regardless of food intake. Babies 1-5 years give 2.5 ml of syrup once a day. Children 6-11 years old are prescribed 5 ml of solution once a day. Adolescents and adults are allowed to take 10 ml of the drug.

Overdose

According to reports of specialists, a drug taken at a dosage exceeding the recommended dose by 9 times did not lead to any side effects. However, in rare cases, patients developed drowsiness. As a treatment, gastric lavage is used. Also, the patient can be assigned the reception of activated carbon.

Adverse Reactions

As evidenced by the reviews of patients, taking this medication can cause side effects. Among the most frequently observed are the following:

• Hallucinations;
• Dizziness, insomnia, drowsiness and psychomotor hyperactivity;
• Abdominal pain, dyspepsia, nausea, diarrhea and vomiting;
• Tachycardia and palpitation;
• Hepatitis, increased bilirubin concentration and liver enzyme activity;
• Myalgia;
• Anaphylaxis, itching, angioedema, hives and rashes.

Drug Interactions

To date, clinically meaningful interaction with other medications has not been identified (including with "Erythromycin" and "Ketoconazole").

It should also be noted that the active substance of the drug does not enhance the effects of ethanol on the nervous system.

Lactation and pregnancy

The purpose of the drug in question during pregnancy is not recommended, as there is no clinical information on the safety of its use in this period.

Desloratadine easily penetrates into breast milk. In this regard, its use during lactation is prohibited.

special instructions

If the patient has severe renal dysfunction, then the drug "Desal" should be administered with extreme caution.

The drug does not have any effect on a person's ability to drive. However, it must be borne in mind that it is rare for some patients to develop drowsiness. In this case, extreme care should be taken when driving and working with complex and dangerous machinery.

Analogues means, the price of the drug

The antiallergic drug "Dezal" can be purchased at any pharmacy. It should be noted that its price is quite high (according to most patients). For 30 tablets you will have to pay about 360 Russian rubles. Approximately the same cost is the drug and in the form of a solution.

If the patient has a contraindicated medicine "Desal", then it can be replaced by an analog. The following medicinal products are characterized by the same composition and action: Desloratadine, Nalorius, Lordestine, Ezlor and Eliseus.

Before replacing the prescribed agent with an analog it is necessary to consult with the doctor. This is due to the fact that such medications can have other side effects and contraindications, as well as dosages and methods of use.

"Desal": patient feedback

Before taking this remedy for allergies, we recommend that you carefully read not only the attached instructions, but also the patient's feedback. With this information, you can learn how to properly take the drug in question and in what dosage.

Reviews about the drug "Desal" (from allergies) are mostly positive. Patients assert that after several receptions of such a drug, symptoms of urticaria practically disappear immediately, the skin itching and rash disappears. Also this medicine perfectly cures allergic rhinitis. It quite quickly eliminates obstruction, itching in the nose and other signs of the disease.

However, in addition to positive, this drug also has negative reviews. According to them, it is ineffective, and sometimes does not have any effect on the allergic reactions that arise.

Experts argue that this happens only with the misuse of the medication, as well as in the absence of the allergy itself. Therefore, before using this remedy, you should always consult a doctor and establish an accurate diagnosis (that is, find out if you are allergic or some other disease that manifests itself in a similar way). Do not be ill!