"Darsil": instruction on the use of the drug, feedback

Hepatoprotectors are drugs that have a positive effect on liver function. Also to this group include agents that are able to protect the cells of the body from any damage. However, it should be noted that the effectiveness of a large number of hepatoprotectors has not been confirmed by clinical trials.

The most popular drug with such properties is the "Darsil" medication. Instructions for use will be given below. Also, you will learn about what kind of reviews about this medicine patients leave, what properties are inherent in it, and so on.

Composition, form and packaging of the preparation

The drug "Darsil", the instruction of which is enclosed in a cardboard package, contains an active compound, like silymarin. In addition, the formulation includes auxiliary substances in the form of potato starch, sugar, lactose monohydrate, calcium stearate, titanium dioxide, magnesium carbonate, talc, aerosil, silicon dioxide, low molecular weight polyvinylpyrrolidone, wax and dye.

In the sale of this product comes in the form of round tablets. They are covered with a shell and packed in contour cells.

Pharmacodynamic properties

What is a "Darcy" drug? Instruction for the use of the drug reports that it refers to phyto-drugs. The complex of flavonoid compounds that make up the drug neutralizes the negative effect of free radicals in the liver, providing a hepatoprotective effect (stabilizes the membranes of hepatocytes and prevents the destruction of cell structures).

It should also be said that this agent stimulates the synthesis of functional proteins and phospholipids that are in damaged hepatocytes, prevents the release of transaminases, activates RNA polymerase and accelerates the regeneration of hepatic cells.

The active substance of the drug slows the penetration of certain poisons and toxins into hepatocytes, including the poison of the pale toadstool. In addition, silymarin blocks the production of acetaldehyde.

After taking "Darsil" in patients, weakness and a feeling of heaviness under the right rib decreases. In addition, treatment with this drug helps normalize blood biochemical parameters and improve the general condition of a person.

Kinetics of the drug

Where is the drug "Darsil" absorbed? Instructions for use indicate that the absorption of this drug occurs in the gastrointestinal tract.

In the systemic blood stream this preparation does not bind to plasma proteins. Moreover, it is not cumulated in the body.

Metabolism of the drug is carried out in the liver. The drug is withdrawn along with the bile within 6 hours.

Indications for taking tablets

What diseases are treated with Darsil medication? Instructions for use, expert reviews indicate that this tool is very effective when:

• Acute and chronic hepatitis of various origin (including viral), as well as post-hepatitis states;
• Cirrhosis and fatty liver;
• Toxic liver damage (for example, poisoning with salts of heavy metals, medicines, pesticides, alcohol and mushrooms).

Contraindications to taking medication

The drug "Darsil", the instruction of which will be presented below, can not be taken with hypersensitivity to the drug, as well as at the age of 5 years, with ulcerative and erosive diseases of the digestive tract (especially during the exacerbation), during breastfeeding and pregnancy, with lactase deficiency And intolerance to galactose.

With special care, this drug is recommended for diabetes and various hormonal disorders, with carcinoma of the ovary, uterus, prostate and mammary gland, uterine myoma, endometriosis.

The drug "Darsil": instructions for use

Experts say that the drug should be taken orally after a meal.

The recommended dosage for adolescents from 12 years and adults is 1-2 tablets three times a day.

For children 5-12 years the daily dose is divided into 2-3 doses and is calculated according to the following scheme: 3 mg / kg of weight.

The duration of this drug is determined individually (depending on the type and severity of the disease). On average, the drug takes about three months.

Adverse events

The "Darsil" tablets, the instructions to which have been described in detail above, are well tolerated by patients. Sometimes against the background of taking this medication, the following side effects are noted:

• arthralgia;
• Dizziness, shortness of breath;
• headache;
• Heartburn, an increase in diuresis;
• Vomiting, flatulence, nausea, diarrhea;
• Local allergic manifestations (alopecia, rash and itching on the skin).

After the drug is discontinued, these symptoms completely disappear.

Drug Interactions

Can I combine Darsil with other medicines? The instruction says that this medicine enhances the action of hypocholesterolemic, antiallergic, antipsychotic and a number of antitumor drugs, as well as anticoagulants and antifungal agents.

One can not but say that silymarin significantly reduces the effectiveness of oral contraceptives and medications for estrogen replacement therapy.

Price, analogues

How much does the drug "Darsil" (tablets) cost? The instruction does not give an answer to this question. You can find out the cost of the medicine in the pharmacy. As a rule, it is 190-200 rubles.

You can replace the medicine in question by such means as "Karsil", "Hepalex", "Legalon", "Karsil forte", "Geparsil", "Silimar", "Hypoglysil".

Reviews

Most reviews about the drug "Darsil" are positive. Consumers say that taking this medication helps reduce pain and discomfort in the right upper quadrant. Moreover, the hepaprotector under consideration eliminates all the consequences that are caused in the process of a violation of the liver function.

Also, the advantages of this drug include its low cost, availability and the absence of adverse reactions.