Chlorphenamine maleate and its properties

Chlorphenamine maleate is currently widely used in pharmacology. This substance is part of a variety of drugs that are designed to treat colds and respiratory diseases, as well as diseases of the ENT organs. It should be noted that this remedy is an effective antihistamine.

Halorfenamine maleate: pharmacological properties

This substance is a widely known blocker that acts on histamine H1 receptors. In connection with a similar mechanism of action, chlorphenamine maleate has excellent antihistaminic, as well as sedative properties. That is why this substance is used as a component of some combined preparations, as the severity of the allergic reaction decreases.

This means acts on the capillaries, reducing the permeability of their walls. It also quickly narrows the lumen of the vessels and removes puffiness. In addition, chlorphenamine maleate removes hyperemia of the mucous membrane of the nasal passages, paranasal sinuses and nasopharynx, thereby facilitating breathing and overall well-being of the patient. This same substance significantly reduces the amount of exudate and relieves allergic symptoms, like itching of the eyes and sneezing.

It is worth noting that chlorphenamine maleate begins to act approximately 20-30 minutes after ingestion into the digestive system. The substance enters the bloodstream, where the corresponding blood protein binds to it. Thus, transport means throughout the body. The duration of its effect is from 4 to 4.5 hours.

Chlorphenamine maleate: indications for use

As already mentioned, this substance has strong antihistamine properties, therefore it is used to suppress allergic reaction and eliminate its main symptoms. It is used to treat rhinorrhea, sinusitis, allergic rhinitis, rhinosinusapathy. In addition, it effectively removes allergy symptoms in infectious and acute respiratory infections.

The agent is not used in its pure form, but is an integral component of some combination preparations. For example, it is a part of such medicines as "Teraflu", "Rinza", "Antigrippin", "Toff", "Koldact", etc.

As for the dose of the drug, this indicator directly depends on the chosen drug.

Chlorphenamine maleate: contraindications and side effects

This substance has practically no contraindications. It is forbidden to take it only to patients who are hypersensitive to its components.

Adverse reactions also appear not too often. Since chlorphenamine maleate has sedative properties, its administration can cause drowsiness, weakness, and sometimes impaired coordination. As a rule, side effects disappear after several days of admission.

Occasionally, rashes or dermatitis may occur. Some patients complain of dry mouth and nose, which is associated with a decrease in secretion of the mucous membrane of the upper respiratory tract. Very rarely as an adverse reaction are constipation, urination disorders, as well as double vision. Sometimes the drug may be accompanied by anemia.