"Captopril" - indications for use.

"Captopril" is a synthetic drug that is used as an ACE inhibitor (angiotensin-converting enzyme). The drug has a blocking effect on the conversion of angiotensin of the first stage into the second, has a vasodilating effect, reduces the overall resistance of peripheral vessels, pressure in the pulmonary capillaries, increases the 60-second volume of the heart and increases resistance to stress. To solve any of these problems, the attending physician may prescribe "Captopril", the indications for which are determined in the course of monitoring the patient's condition for outpatient or inpatient treatment. With prolonged use of the drug, the risk of myocardial hypertrophy in the left ventricle decreases, the progression of heart failure decreases, and the dilatation of the left ventricle decreases. Reduces the tone of the glomeruli of the kidneys, which improves hemodynamics inside the glomeruli of the kidneys and prevents the development of nephropathy in diabetes.

In case of heart failure, hypertension, arterial hypertension, diabetic nephropathy against the background of insulin-dependent diabetes mellitus , "Captopril" is used in treatment. Indication for the use of the drug: a complex terpia with myocardial infarction, with angina pectoris and with chronic kidney disease. The attending physician with mild and moderate form of arterial hypertension, with signs of heart failure and with a violation of left ventricular function, accompanied by a general stable condition of the patient, also uses "Captopril". Indications for use may cause the use of other drugs, similar to "Captopril" for its pharmacological properties.

Contraindications to the prescription of the drug are the presence of the patient's stenosis of the renal arteries, hyperkalemia, hypersensitivity to the drug. Not allowed treatment "Captopril" of pregnant women and women during lactation.

The drug "Captopril" is not assigned to children, as well as patients with severe renal dysfunction, to patients who are on hemodialysis. Increased levels of nitrogen in the urine and blood, creatine in the serum in patients with BCC can be provoked by the designated "Captopril". Indications for use of the drug are considered taking into account the general condition of the patient and the course of the disease.

Tablets "Captopril" take inside an hour before eating. In case of arterial hypertension, treatment is prescribed with a primary dose of 12.5 mg twice a day. The doctor controls the tolerability of the drug within the first hour after admission. If in this period of time arterial hypotension develops , the patient is transferred to a horizontal position. The reaction to the first dose of the drug "Captopril" does not serve as a basis for refusing treatment with this drug. Monotherapy "Captopril" gives a positive effect with a simultaneous decrease in the intake of the patient with Na +. Course treatment is carried out with increasing dose in 2 weeks to 50 mg three times a day. With arterial diastolic pressure of 115 mm Hg. The drug is combined with antihypertensive medicinal forms, such as thiazide diuretics (hydrochlorothiazide with a daily dose of 25-40 mg). Dosage of the diuretic is carried out with an increase in the interval after one, two weeks. During treatment should monitor the function of the kidneys. Possible side effects: dizziness, arterial hypotension, headache, nausea, a feeling of fatigue, asthenia. Rarely are allergic reactions, diarrhea, abdominal pain, taste disorders. In this case, the treating doctor prescribes another medicine that is easily tolerated by the patient.