Instructions for the use of "Fucis". Futsis DT: instructions for use

Uncontrolled intake of various medications, especially antibiotics, as well as inaccuracies in nutrition lead to the fact that in the body there is an increased growth of pathogenic microflora. This process inevitably ends with the appearance of various diseases, one of which is the well-known thrush.

This problem gives a lot of trouble to its "mistress", which manifests itself in the form of burning, itching, curdled discharge from the vagina. Coming to the pharmacy for getting rid of this scourge, it's quite easy to get confused in the assortment of antifungal agents that are flamboyant on the shelves. In this article we will talk about one of these means, and the instructions for the use of the drug "Fucis" will be examined in detail.

Composition of the preparation and form of release

The manufacturer produces the drug in the form of several forms:

• Tablets for oral administration.
• Dispersible tablets.
• The medicine is in the form of a gel.
• Solution for infusion.

Consider the composition of the drug. If we talk about tablets, then they include the main active substance - fluconazole, the amount of which can vary depending on the weight of the tablet. They can be from 50 to 200 mg.

As auxiliaries in the tablet form are:

• Microcrystalline cellulose.
• Lactose monohydrate.
• Povidone K30.
• Talc.
• Magnesium stearate.
• Sodium starch glycolate.
• Sodium croscarmellose.
• Isopropyl alcohol.

Instructions for the use of "Fucis" in the form of dispersible tablets contain information on the content as additional components of sodium saccharin, flavor "American ice cream" DC129, as well as aerosil.

The preparation in the form of a solution contains 200 mg of fluconazole soluble in 100 ml of physiological sodium chloride solution.

Such a dosage form as a gel contains 5 mg of fluconazole as its main substance, and as additional components there are:

• Carbomer.
• Benzyl alcohol.
• Polysorbate 80.
• Propylene glycol.
• 2-octyldodecanol.
• Sodium hydroxide.
• Aromatizer De-lite.
• Purified water.

What form of the drug should be chosen for the treatment of thrush should be determined by the doctor, taking into account the patient's condition and the characteristics of his organism. For example, if mild form of the disease is enough, it will be enough to use for therapy "Fucis 50", the instruction for its use contains detailed information on the treatment regimen and possible contraindications.

What is the effect of the drug

"Fucis" belongs to a group of medical products that have a pronounced antifungal effect, and on a wide group of microorganisms. As a result of the penetration of the drug into the body, the cells of yeast fungi lose their enzymatic activity. In the cells of the fungus, the biosynthesis of ergosterol is disturbed, which leads to the appearance of holes in the cell membrane, and this results in its death.

If the doctor appoints "Fucis", the instruction for the use of the 150 mg tablet from the yeast infection recommends first of all to determine the sensitivity of the flora, since not in each case such therapy can be effective.

Given that the half-life of the main active substance is more than a day, this makes it possible to apply the medicine only once every 24 hours. Fluconazole is well distributed throughout the body, its concentration in tissues and fluids is almost the same as in plasma.

The instruction for the use of Fucis says that most of the medicine is excreted by the kidneys.

Indication for the use of "Fucis"

This drug is used for various infectious diseases caused by fungi and having different localization. The most important thing is that they are sensitive to fluconazole.

If "Fucis" is chosen for treatment, the instruction for the use of the 200 mg tablet contains information about the problems in which such treatment will become effective. The following diseases can be noted:

• Candida.
• Candiduria.
• Various forms of candidiasis.
• Infectious diseases of the organs of vision.
• The urinary system.
• Respiratory organs.
• Infectious diseases of mucous membranes caused by Candida fungus.
• Candidiasis of the bronchopulmonary system.
• Fungal infection of the oral cavity in chronic form.
• Vaginal candidiasis in acute or chronic form.
• As a preventive agent in patients with chronic candidiasis.
• Balanitis candidiasis.
• Cryptococcal meningitis.
• Dermatomycosis.
• Onychomycosis.
• Pityriasis lichen.
• Endemic mycoses.

Instruction for the application of Fucis asserts that the drug is effective enough as a prophylaxis of the spread of fungal infection in patients who have immunodeficiency or who are undergoing cytokinetics or radiation therapy.

"Fucis" in the form of a solution for injection is used usually with systemic fungal infections. This includes all those diseases that were listed earlier.

Who is contraindicated with the drug

Any medication has contraindications to use, not an exception, and "Fucis" 200. The instructions for use warns that there are conditions in which therapy with this drug is undesirable:

1. If there is excessive sensitivity to the components of the drug.
2. During pregnancy, such treatment is prohibited.
3. Contraindication is the period of breastfeeding.
4. If you get acquainted with the drug "Futsis", the instruction on the use of the 50 mg tablet warns that this form is contraindicated for children under 7 years old. Dispersed tablets can be given to babies after three years.
5. You can not use Fucis if the patient is treated with Terfenadine or Cisapride.
6. The drug has an effect on the ability to concentrate and respond quickly, so during therapy it is undesirable to drive and perform dangerous work.
7. "Fucis" in the form of a gel is contraindicated for use up to 18 years.

Before starting therapy with the drug, the Futsis instruction manual recommends discussing this issue with the attending physician.

Undesirable manifestations

Even if the patient does not have contraindications to the use of this medication, this does not mean that he will be circumvented by side effects during treatment. And they can be:

• The appearance of dizziness and headache.
• Some patients complained of cramps and tremors of the extremities.
• Should be well studied by patients suffering from cardiovascular diseases, to the "Fucis 200" instructions for use. Tablets can trigger arrhythmia or tachycardia.
• Some complain about changes in taste.
• The gastrointestinal tract can respond with nausea, vomiting, or pain in the epigastric region.
• Diarrhea may occur.
• In some cases, the development of hepatic insufficiency was diagnosed.
• Exfoliative skin reactions.
• Allergic manifestations in the form of hives, itchy skin, small rashes. In more serious situations, there is a risk of developing Quincke's edema or Stevens-Johnson syndrome.
• If a blood test is performed during the treatment period, it often shows leukopenia, agranulocytosis, or thrombocytopenia.
• It is possible to increase the level of cholesterol in the blood.

All these manifestations do not depend on the dosage of the drug "Fucis", the instruction for the use of the 150 mg tablet contains a list of the same side effects.

Scheme of therapy with Fucis

With what dosage of active ingredient to appoint tablets and for how long - only the doctor determines the results of the examination. Dosage usually does not depend on the way the drug is used.

If you select the drug "Fucis" 200 mg, instructions for the use of the drug in different age groups pays much attention. It is allowed to use them in the therapy of adult patients, as well as children who are already 7 years old. Tablets are usually taken orally, they can be consumed at any time of the day and not coordinated with food intake. Most often the entire recommended dose is taken once a day.

Now consider in more detail the dosage and treatment regimen for various diseases:

1. In the presence of invasive forms of candidiasis, the doctor usually prescribes 2 tablets of 200 mg on the first day of treatment, and then the dosage is reduced to 200 mg. If the infection has a severe degree, then 400 mg is preserved.
2. Patients suffering from oropharyngeal candidiasis are usually prescribed 1-2 tablets of 50 mg once a day. If the patient's immunity is normal, then the duration of the course is up to two weeks, with a reduced immune status, the therapy is longer.
3. When candidiasis of the oral cavity (it is often provoked by wearing dentures), it will be enough to take 50 mg of the drug once every 24 hours. The duration of therapy with simultaneous administration of antiseptics is two weeks.
4. For the prevention of candidiasis in patients with immunodeficiency appoint "Fucis 150", the instruction for use recommends taking the medication once every 7 days after the completion of primary therapy.
5. In the presence of non-invasive infections of the mucous membranes, 50-100 mg of the medication is prescribed most often once a day for two weeks. If necessary, the course can be extended to 28 days.
6. With genital candidiasis will also help "Fucis", the instruction for the use of a tablet of 150 mg asserts that a single dose will be enough. To prevent relapses, one tablet should be taken once a month for six months.
7. Patients with an increased risk for the prevention of candidal infection should receive from 50 to 400 mg of "Fucis" once a day a few days before the proposed neutropenia.
8. If cryptococcal meningitis is diagnosed, then 400 mg of the drug is taken on the first day of therapy, and then 200 times a day. The duration of such treatment is usually not less than 6-8 weeks.
9. In the presence of fungal skin lesions, 150 mg once a week or 50 mg every day is recommended. The duration of treatment depends on the severity of the disease and can range from 14 days to 2 months.
10. Patients suffering from pityriasis, recommend 2 tablets of 150 mg once a week. The duration of the course can vary depending on the complexity of the disease.

If the elderly patients are healthy, the dosage adjustment is not required. In the presence of problems with the kidneys, "Fucis" at the beginning of therapy is prescribed in a dosage of 50 to 400 mg, and then, depending on the creatinine clearance.

The use of the drug in the therapy of children

It has already been repeatedly said that the drug can be used only in children older than 7 years. Dosage in each case is prescribed only by a doctor. It should be borne in mind that the daily dose should not be more than that of adults.

If the child has candidal infections of the mucous membranes, the drug is prescribed at the rate of 3 mg per kilogram of weight 1 time per day. On the first day of treatment, the doctor can appoint a single impact dose of 6 mg per 1 kg of body weight to achieve the maximum concentration of fluconazole in the body.

As a prophylactic, Fucis can be administered to a child at a dose of 3 to 12 mg per kilogram of body weight. It must be remembered that the course of treatment can be stopped only when negative test results are obtained.

Features of the application of "Fucis" in the form of dispersed tablets

In the form of dispersed tablets, Fucis DT is produced. Instructions for use advise before use dissolve the pill in a teaspoon of water, if the tablet is 50 mg. In this form, the drug is allowed to use by adults, as well as babies from the age of three.

If there is a candidal infection in the oral cavity, you will need to dissolve the drug in an amount of 50-100 mg in a small amount of water and rinse the oral cavity. Then the solution must be swallowed. This procedure should be done once a day for two weeks.

For other indications, the drug is prescribed according to generally accepted recommendations.

Carefully should be studied by patients with reduced immunity to Fucis DT instructions for use, tablets such patients will have to take much longer.

The application of "Fucis" in the form of gel and solution

If a woman is diagnosed with thrush, then it is possible to use a gel for treatment. It must be remembered that it is advisable to take therapy simultaneously with a partner. In 1 gram of the drug contains 5 mg of the main active substance.

Very convenient to use "Fucis" -gel, the instruction for use recommends once to lubricate them affected areas of the fungus. Before spreading the gel, you need to cleanse the skin. Numerous reviews confirm the effectiveness of the drug in this form, only the duration of therapy is slightly increased.

You can not use "Fucis" -gel during pregnancy, the instructions for use with thrush allow it to be used only if the risk from such therapy is lower than the threat to the fetus.

The gel can also be used to treat oral candidiasis in young children. Only it is not necessary to independently appoint such therapy, consultation of the expert is necessary.

If there is a need to use the drug "Futsis" in the form of a solution for infusions, then for adults and children older than 3 years the dosage does not change. It is necessary to pay attention to the scheme of treatment in infants. If it is required to administer a newborn not older than 4 weeks, then the drug is prescribed in the same doses as the elder, but inject it only once every three days. This is in view of the fact that excretion of the drug occurs much more slowly from the body.

From 4 weeks to 3 years, the drug should be administered in the same dosage, but once every two days. When treating babies with "Fucis" it is necessary to closely monitor the child's condition and manifest undesirable effects.

Interaction of "Fucis" with other drugs

If you take the drug at the same time with anticoagulants, then the effect of their use increases, so during this therapy it is worthwhile to monitor prothrombin time.

There is a risk of developing psychomotor reactions, if you designate "Futsis" at the same time as "Midazolam." The administration of the drugs "Benzodiazepine" and "Fucis DT" recommends the use under strict supervision of the doctor.

On the background of fluconazole therapy, when taking "Cisapride", side effects are more pronounced, especially from the side of the cardiovascular system. It is because of this that the two drugs are not administered simultaneously.

It will be necessary to correct the dosage of "Ciclosporin" with simultaneous treatment with "Fucis", as there is an increase in the plasma concentrations of the first drug.

In practice, there was no decrease in the effectiveness of hormonal contraceptive use during simultaneous admission with "Fucis". If Rifabutin therapy is administered, the addition of fluconazole may lead to the development of inflammatory diseases of the choroid of the eye.

In patients with diabetes mellitus, the "Fucis" method promotes an increase in the period of excretion of sulfonylureas, therefore there is a risk of developing hypoglycemia.

Patients suffering from kidney disease should be carefully treated with this medication, since there is a risk of simultaneous admission of "nephrotoxicity" with "Tacrolimus".

Absorption of the drug is not dependent on food intake or antacid preparations.

Some guidelines for the therapy of "Fucis"

We have already considered the side effects that can occur during therapy with this drug. This does not mean that they will necessarily appear, but it is necessary to know about them.

But there are still some special instructions for the application of Futsis. If the patient suffers from serious liver disease, then it is not worth the risk of prescribing treatment with this medication. There were cases when such therapy ended in a lethal outcome, as the toxic damage to the liver began.

Hepatoxic effects are reversible, and if it is time to notice and cancel the drug, then all the indicators come back to normal.

"Fucis" may provoke anaphylactic reactions in some patients, so patients from such a risk group should be kept under medical supervision.

Patients diagnosed with AIDS most often undergo skin reactions that occur in a rather severe form. If the appearance of a rash on the body is associated with the treatment of "Fucis", then its reception must be canceled.

If rashes appear in patients with invasive systemic fungal infections, then careful monitoring is necessary. And with the development of multiform erythema, therapy should be discontinued.

In patients with cardiovascular problems, taking this medication can cause an increase in the QT interval on the cardiogram. In addition, there may be a flutter of the ventricles. More often such undesirable manifestations were diagnosed in patients with organic heart diseases, electrolyte balance disorders. If there is such a danger, then treatment should be carried out with great care, and if possible, you need to think about replacing the drug.

If there are liver and kidney diseases, even in an anamnesis, then, before starting therapy Fucis, it is worth consulting with a doctor. If "Fucis" -gel is prescribed, the instructions for use explain that the desired effect will be achieved a little later than during the treatment with tablets.

If, after the start of therapy, several days have passed, and there is no improvement in the condition, it is worth informing the doctor about it. Maybe it happened that fungi were incorrectly identified, and therefore the drug does not have the desired effect.

Any disease, even at first glance quite simple, requires a thorough approach to treatment. Only a properly selected drug can give a 100% guarantee of getting rid of the disease. Do not self-medicate, sometimes it is expensive for health.