"Neovir": instruction on the use of injections, description of the preparation

"Neovir" is an immunostimulating drug that has antiviral activity against DNA and RNA genomic viruses. The activity of the drug is due to its ability to cause the formation of high concentrations of endogenous interferons.

Composition and form of the preparation "Neovir": The instruction describes the medicine in the form of a transparent, greenish-yellow solution for intravenous injections. In 1 ampoule of the drug, in 2 cm3 of the solution contains the active substance -oxodihydroacridinylacetate sodium, in an amount of 250 mg, and additional substances in the composition: sodium citrate, citric acid, water d / u.

Pharmacological action of Neovir solution: The instruction defines the preparation as an immunostimulating agent that has activity against DNA and RNA genomic viruses, including chlamydia and HIV pathogens. The effect of the drug is based on its ability to optimize the formation in the body of significant concentrations of endogenous interferons, including. Interferon alfa. The drug "Neovir" promotes the activation of stem cells in the bone marrow, T-lymphocytes and macrophages. Has immunomodulatory activity, normalizes the ratio of subpopulations of T-helpers and T-suppressors. In some diseases, the drug "Neovir", the instruction indicates that it reduces the production of the substance by the substance of tumor necrosis and activates the killer cells. It causes a significant increase in the activity of polymorphonuclear leukocytes. In the presence of HIV infection, the drug "neovir" acts immunomodulating: the absorption capacity of blood serum increases, the activity of leukocytes increases in the synthesis of interferon alfa, the production of phagocytes by active compounds of oxygen is stimulated. The highest activity of interferons in the body is achieved 2-3.5 hours after Neovir's injection and lasts 16-20 hours.

Indications for use of the drug "Neovir": The instruction provides for the use of the drug as an immunostimulating agent in the combined treatment for: prevention and treatment of influenza and other acute respiratory viral infections (including in the presence of immunodeficiency states); Infections caused by herpes virus type 1 and type 2, the virus Varicella zoster; Cytomegalovirus infection in immunocompromised individuals; Radiation immunodeficiency; Treatment of HIV infection; Encephalitis and encephalomyelitis of viral etiology; Acute and chronic hepatitis B and C; Urethritis, epididymitis, prostatitis, cervicitis and salpingitis of chlamydial etiology; Venereal lymphogranuloma; Oncological diseases; Multiple sclerosis; Candidiasis of the skin, mucous membrane.

Methods for the administration of the drug "Neovir": Instructions for use prescribe the solution to inject IM , 250 mg (1 amp.). If necessary, a single dose of the drug "neovir" can be increased to 500 mg (0.5 g).

The course of treatment with Neovir is injections: It usually consists of 5-7 injections of IM, with an interval of 48 hours. The dose is determined by the clinical picture. The duration of the course of therapy is 8-12 days. For prolonged and preventive use, the interval between injections should be 3-7 days.

In the treatment of HIV infection, the drug "Neovir" is used in combination therapy. The course of therapy includes 10 in / m injections of 250 mg, with an interval between them - 48 hours. After the course is necessary to break in 2 months. You can repeat the courses unlimitedly.

Side effects: In the form of general reactions (subfebrile temperature, allergic reactions). In the form of local reactions - local fast-passing soreness at the injection site.

Contraindications: Do not appoint if: severe renal failure; Autoimmune diseases; Pregnancy; Lactation (breastfeeding); Childhood; Hypersensitivity to the components of the drug. It requires cautious use in the elderly.

Special instructions: If the drug is not well tolerated or the site of the injection is painful, it is recommended to inject with a solution of novocaine.

Overdose: There is no information about an overdose.

Interaction: Clinical studies and practice have not established the incompatibility or influence of the drug "neovir" when combined with other medications.