The drug "Veroshpiron." Reviews

The drug "Veroshpiron" comes in the form of flat round tablets, painted in white and having a characteristic mercaptan smell. On one side is the brand name "VEROSPIRON".

One tablet contains twenty five milligrams of spironolactone, the active ingredient. Additional components include: colloidal silicon dioxide, magnesium stearate, corn starch, talc and lactose monohydrate.

The drug "Veroshpiron", reviews of which indicate its popularity, goes on sale in blisters for twenty tablets (in a cardboard package).

The drug is a potassium-sparing diuretic, a competitive aldosterone antagonist.

The greatest effect of this drug is after seven hours after its administration. Lasts for at least 24 hours. Diuretic effect is observed on the second-fifth day of regular use of the drug Veroshpiron.

The reviews inform that such side effects as nausea, loose stools, vomiting, bleeding and ulceration in the gastrointestinal tract, gastritis, constipation, intestinal colic, abdominal pain, and liver function failures may occur with this medication.

In the course of the studies, it was found that the drug in question can be absorbed completely and fairly quickly from the gastrointestinal tract. Its bioavailability is equal to one hundred percent. It has been established that after a regular daily application of one hundred milligrams of the preparation "Veroshpiron" for two weeks, the maximum active active ingredient concentration is 80 ng / ml.

This drug is 98 percent associated with proteins contained in the blood plasma.

The half-life period is from thirteen hours to days after taking the drug. With urine, a large part of the drug is excreted, and only partially - with mucus masses. It is noted that in patients with cirrhosis of the liver, chronic renal failure and hyperkalemia, this process takes more time.

The drug "Veroshpiron" (reviews confirm this) helps to cope with essential hypertension and edematous syndrome with heart failure (chronic). In addition, it is used to treat conditions that are characterized by the presence of secondary hyperaldosteronism - cirrhosis, nephrotic syndrome and other ailments accompanied by edema. If it is not possible to use alternative ways to normalize the potassium content, the medication in question is used to eliminate hypokalemia or hypomagnesemia. In hospital conditions, the "Veroshpiron" is used for a short course of preoperative therapy.

Recommended dosage

To treat essential hypertension, the daily volume is usually fifty to one hundred milligrams (it can be increased to two hundred, but it needs to be done gradually). To obtain the maximum result, it is recommended to use the drug regularly for fourteen days.

Note: "Veroshpiron" is not prescribed for children. The above dosages are suitable for adult patients.

The drug "Veroshpiron", consumer reviews indicate this, has the following overdose symptoms: thirst, nausea, drowsiness, dizziness, itching sensation, rash, arrhythmia and muscle weakness.

The drug "Veroshpiron" during pregnancy is not appointed. Contraindications are also the presence in the anamnesis of Addison's disease, hyperkalemia, hyponatremia, severe renal failure, anuria.

Shelf life of the drug is five years.