The drug "Nifedipine": instructions for use

The drug "Nifedipine" is used for the expansion of coronary and peripheral vessels, mainly arterial. It has a negative ionotropic effect, significantly reduces the need for myocardium in oxygen and does not strongly inhibit the conduction of the cardiac system. Reduces pressure and significantly reduces the resistance of peripheral vessels.

The drug "Nifedipine", the instruction on which application speaks about the ways of its effect on a person, when taken very quickly gets into the blood. Literally after half an hour its maximum concentration in plasma is observed. But, having a short half-life, equal to 2-4 hours, the substance is rapidly excreted from the body. However, with long-term medication, the organism becomes accustomed to its action.

INDICATIONS: The drug "Nifedipine", the use of which is strictly controlled by a physician, is usually prescribed for angina pectoris, symptomatic and essential hypertension, to reduce blood pressure.

It is used in the treatment of heart failure, in combination with other drugs, improves heart function, while helping to reduce its size. There was also a decrease in pressure in the pulmonary artery.

There is information about the positive effect of the drug "Nifedipine" on cerebral hemodynamics, as well as on the effective use of Raynaud's disease.

For maintenance therapy in combination with other drugs, the drug can be used as a bronchodilator.

APPLICATION: It is administered orally, in a day 3-4 times for 10-30 mg, regardless of food intake. When hypertensive crisis can be used as a solution in a dose of 10 mg. If necessary, repeat in half an hour, you can increase the dose to 30 mg or in the amount of 5 mg to administer the medication for 4-8 hours. The maximum dose should not exceed 30 mg.

CONTRAINDICATIONS: The drug is categorically contraindicated in pregnant or lactating.

Tablets "Nifedipine" can not be used for arterial hypotension, pronounced heart failure, porphyria, hypersensitivity to the drug, unstable angina.

Caution should apply the drug to drivers and those whose work requires a quick mental and physical reaction.

ADVERSE EFFECTS: Although the drug Nifedipine is usually well tolerated, the instructions for use indicate some side effects.

If the patient has unusual drowsiness, progressive headache and dizziness when taking the medication, it is necessary to lower the dose. Tachycardia, edema of the lower extremities, redness of the skin of the trunk and face, or nausea may also appear. In addition, palpitation, lowering of blood pressure is possible.

SPECIAL INSTRUCTIONS: Older people when treated with Nifedipine (instructions for use indicate this) should be closely monitored by a health professional.

Patients with diabetes, myocardial infarction and unstable angina should use the drug with extreme caution, because the resulting reflex tachycardia can significantly exacerbate the chronic disease.

INTERACTIONS: Medications "Nifedipine" can not be taken at the same time as other antihypertensive drugs.

Treatment with the drug should be discontinued one day before the planned anesthesia with fentanyl.

OVERDOSE: In case of an overdose of Nifedipine, the instructions for use indicate some symptoms. For example, there is arterial hypotension, heart failure, shock, convulsions. It is recommended that gastric lavage, control of hemodynamic parameters, reception of activated charcoal and symptomatic treatment.

FORM OF ISSUE: The drug is available in tablets coated with a coating and containing 10 mg of the drug, as well as in a solution in vials of 50 ml or 2 ml in ampoules.

STORAGE CONDITIONS: Store in a dark place. Refers to list B.