The analogue of "Vilprafen" - is it?

Among the certified and harmless medications, the drug "Vilprafen" is known as an antibiotic belonging to the pharmacological group of macrolides, lincosamides and streptogramins. It is customary to prescribe in the fight against bacterial infections, which are caused by sensitive microorganisms. The effective effect of the drug in cases of respiratory tract infections and dental infections , urogenital system lesions and infections of cutaneous soft tissues and tissues, gonorrhea and ureaplasmosis, chlamydiosis and syphilis, microplasmosis and similar infections was noted. The analogue of "Vilprafen" - the drug "Clarithromycin" - is used only as an alternative.

pharmachologic effect

Vilprafen or in other words - Josamycin has a high activity in relation to intracellular organisms, but along with erythromycin the emergence of resistance is not induced. High concentration of the drug in the tissue lesions has a clear bactericidal effect and has a negligible effect on enterobacteria. This means that the natural bacterial flora does not change in the stomach.

Kinetics of admission

The ingestion of food does not at all impede the bioavailability to the properties of the preparation. Because it is easily and quickly absorbed from the gastric tract into the circulatory system. Within a couple of hours after the use of the drug "Vilprafen" in serum, the maximum concentration is achieved. Plasma proteins bind to molecules of josamycin, the main active substance of this drug, and its concentration reaches 15%. A particularly high percentage is observed in the tonsils and lungs, phlegm, tear fluid. The drug can accumulate in bones, tissues and secreted in breast milk after passage of the placental barrier. The metabolism of josamycin to weakly active metabolites occurs in the liver. The conclusion is with bile. Excretion through the urethra is about 20%.

Josamycin - the main component of the drug "Vilprafen"

It is the fact that Josamycin is the sole substance of importance in the composition of the drug, the analogue of "Vilprafen" does not exist.

The main factor that worries people when buying Vilprafen is a rather expensive treatment that lasts longer than 10 days. Pass it to achieve a quality effect you need to completely and daily take pills. "Vilprafen" with all the positive reviews about the drug has a high enough price, and therefore people are constantly looking for an affordable and similar analog. Some experts recommend the use of the drug "Clarithromycin" as an alternative to the "Vilprafen" analogue.

Find an analogue of "Vilprafen" to many advances that its use is not forbidden by pregnant women, it is possible to use breastfeeding mothers, and it is harmless for young children. With the known absence of embryotoxic effects, the preparation "Vilprafen" is prescribed only after carefully evaluating the risk or benefits of treatment.

The medicine "Vilprafen" and its combination with alcohol

The instruction accompanying the preparation does not contain indications of the interaction of alcohol and the active substance of josamycin. The medicine "Vilprafen" and alcohol - a bad combination. A sensible person should not forget that alcohol has always had a harmful effect on the liver - the main body that removes medicines from the body. It seems that severe violations of the liver will provoke an abnormal outflow of bile and the intake of alcohol is highly undesirable. The permissible daily rate can be as much as 200 milligrams of alcohol and this is provided that there is no increased activity of liver enzymes in the plasma.