"Prajisan": reviews, instructions, application

Why does humanity need hormonal drugs? Hormones (from the Greek "I encourage", "put in motion, stimulate") are the product of endocrine glands functioning. The influence of these substances manifests itself distally, at different distances from the gland in which they are formed. Effects from the effects of hormones are diverse and unique.

Many human hormones are synthesized in the human body. Sometimes, against the backdrop of various diseases, the activity of the endocrine system may decrease and, as a consequence, their production (hormones) decreases. To bring the situation to normal, hormonal preparations are needed. One of them is Prajisan. Reviews of patients and specialists characterize this substance as an excellent tool for treating diseases of the female sexual sphere.

Pharmacology

The drug is the hormone of the yellow body. With his direct involvement, the phase of the mucous membrane of the uterus changes: from the state of proliferation, it passes into the secretory phase. Thus, "Prajisan" (doctors' reviews and information on instructions for use confirm this) creates optimal conditions for implantation in the mucosa of a fertilized egg.

In addition, under the influence of this hormone decreases the sensitivity of the uterus to a substance such as oxytocin, relaxes its muscles. Prajisan helps to increase fat reserves, increase insulin levels (induced and basal), affect the effective utilization of glucose, stimulate the accumulation of glycogen in the liver.

Also "Prajdisan" reviews have as a good remedy, a suppressive synthesis of hypothalamic factors releasing FSH, LH. In the tissues of the breast, the hormone helps to reduce the permeability of capillaries, reduces the swelling of the connective tissue stroma.

In what cases is it appointed?

All the most important and complete information contains about the hormonal preparation "Prajisan" (capsules) instructions for use. The reviews describe the drug as very effective in such problems as secondary amenorrhea, infertility caused by a deficiency of lutein, dysfunctional uterine bleeding, a consequence of a lack of progesterone.

Sufficiently widely, "Prajisan" is used as a component of hormone replacement therapy in tandem with estrogenic medicines in the post-menopausal period. Also, this hormone is used to support the luteal phase in cases where additional reproductive techniques are used.

Methods of medicament use

If the level of progesterone is insufficient, the capsules of "Prajisan" are taken in a daily volume equal to 200-300 mg. Frequency of admission - twice during the day. Determining the duration of the course of therapy is the prerogative of the doctor, everything is very individual and depends on the severity of the state of health.

The daily dose of the drug with a luteal phase deficiency can range from 200 to 400 mg. The duration of therapy is 10 days (strictly 17-26 days of the menstrual cycle).

During the peri-and post-menopause "Prajisan" (reviews of patients claiming high effectiveness of the drug) is taken at 200 mg per day in parallel with estrogens. The duration of the course is 10-12 days.

It is possible to use this hormone in the preparation for IVF in the form of capsules for vaginal administration. Duration of admission - until the onset of pregnancy.

When treating infertility, which is caused by luteal insufficiency, the "Prajisan" gel is used. The duration of the course is 10 days.

When and who should refrain from using Prajisan?

Like any hormonal remedy, there are contraindications to the medication "Prajisan". Reviews, instructions the use of this tool is prohibited in those cases when the patient has such pathological problems as porphyria, vaginal bleeding of unknown origin, malignant neoplasms of genital organs or mammary glands.

Contraindicated this medication and those who suffer from thrombophlebitis, thrombosis and any other thromboembolic diseases. Do not appoint "Prajisan" for acute disorders of cerebral circulation and with severe liver disease.

Increased individual sensitivity to the main and auxiliary components of the medication is also a contraindication for taking the drug.

Pregnancy and Prajisan

A separate topic for conversation is "Prajisan" during pregnancy. The experts' comments do not speak of persistent contraindications or indications. The fact is that the lack of the level of progesterone in the body of a pregnant woman carries the threat of abortion. In such cases, the attending physician usually prescribes a course of appropriate therapy to enable the woman to safely endure the child. Prajisan is one of the possible options.

If the level of progesterone in the expectant mother is normal, then the woman will certainly put herself and the child at risk by taking the medication in the first half of pregnancy (16-18 weeks).

Also, one should not lose sight of the fact that taking the Prajisan during pregnancy (expert reviews confirm this fact) in the period from 12 to 40 weeks of bearing a baby, the patient risks acquiring serious enough liver diseases.

Side effects

Patients who took Prajisan say there are some side effects from different organs and systems. The cardiovascular system can respond by increasing blood pressure. From the side of metabolism, pronounced reaction to "Prajisan" (reviews of specialists testify to this) are considered edemas. The digestive system is capable of declaring itself a violation in the functioning of the liver, the development of jaundice. With prolonged use, nausea and vomiting may occur.

Also, when applying Prajisan for a long time, it is possible to reduce libido, weight gain, pain and a feeling of tension in the mammary glands, uterine bleeding (irregularly). The possible reaction of the central nervous system with prolonged reception is depression, skin rash, itching, headaches. Quite often, patients talk about the appearance of a feeling of fatigue after taking the medication.