Nurofen Express: instruction

The medicine "Nurofen Express", whose composition includes ibuprofen, belongs to the category of NSAIDs, a derivative of phenylpropionic acid. It has anti-inflammatory, antipyretic and analgesic effects. The mechanism of drug effect is based on the ability to slow down the synthesis of prostaglandins due to the blocking of cyclooxygenase enzymes. From the digestive system, the drug is absorbed quickly enough. The connection with proteins occurs by 90%. The drug is slowly transported into the articular cavity, accumulates in the synovial tissue, it forms larger concentrations than in plasma. The drug is metabolized in the liver. The active substance is excreted in the urine and in an insignificant quantity with bile.

The medicine "Nurofen Express". Instructions. Indications

The drug is recommended for dental, head, rheumatic pains, migraine, algodismenorea. Indications include neuralgia, back pain, fever on the grounds of acute respiratory disease and influenza.

The drug "Nurofen Express." Instructions. Contraindications

The agent is not recommended for heart failure of a pronounced nature, arterial hypertension in severe course, lesions in the gastrointestinal tract of the erosive or ulcerative type in the acute stage. The drug "Nurofen Express" instruction does not admit to the appointment with leukopenia, "aspirin" bronchial asthma, urticaria, caused by treatment with acid acetylsalicylic and other NSAIDs. Contraindications include hemorrhagic diathesis, the state of hypocoagulation, disorders in the activity of the kidney or liver, pregnancy, lactation. Medication is not prescribed with hearing loss, in children (up to six years old), with pathologies in the vestibular apparatus, as well as with intolerance of the components of the remedy.

Dosing regimen

The drug "Nurofen Express" (tablets) is prescribed for 200 mg of patients from twelve years three or four times a day. If necessary, a quick clinical effect of the dose is increased to 400 mg three times a day. A day is not allowed to take more than 1200 mg. For children from 6 to 12 years, 200 mg are prescribed not more than four times. The drug is recommended for patients weighing more than twenty kilograms. Between reception of tablets the interval should be not less than six hours. Effervescent tablets are dissolved in a liquid (water), coated with a coating - swallowed whole and washed down.

The drug "Nurofen Express." Instructions. Side effects

When taking medication for two to three days, there are almost no adverse events. With prolonged therapy, there is a risk of nausea, hepatitis, constipation, pancreatitis, reversible optic neuritis. The drug can cause diplopia, flatulence, heartburn, a feeling of discomfort in the epigastrium, increased pressure, tachycardia. Some patients may experience leukopenia, allergic rhinitis, dyspnea, increased sweating during treatment. The drug can sometimes provoke cystitis, polyuria, nephrotic syndrome, anemia, agranulocytosis.