Description and instructions for use: "Albarel"

What is the drug Albarel? Instructions for use and a description of this medication will be discussed below. Also, we will tell you about the form in which this drug is produced, how remarkable it is, how patients respond about it.

Composition, description, form

In what form is the medicament under consideration? What does the instruction for use say? "Albarel" is a round, biconvex tablets of white color, which have the same engraving on both sides in the form of the sign "H".

The medicine is packed in blisters of 10 pieces and a cardboard pack, respectively.

What is included in the drug "Albarel"? Instruction for use reports that the active element of this agent is rilmenidine. It also consists of inactive auxiliary ingredients in the form of sodium carboxymethyl starch, MCC, solid paraffin, lactose, magnesium stearate, colloidal anhydrous silica dioxide, talc and white beeswax.

Pharmacology

What is the said drug? What does the instruction for use say? "Albarel" is an antihypertensive agent, as well as an oxazoline derivative.

After application the medication enters into interrelation with imidazoline receptors of peripheral and cortical vasomotor centers, including renal centers. The interaction of rilmenidine with these elements helps to inhibit the sympathomimetic activity of peripheral and cortical centers, which ultimately leads to a decrease in blood pressure.

Features of the medicine

The drug "Albarel", analogues, instructions for use of which are presented below, has an antihypertensive effect (depending on the dosage taken) on diastolic and systolic blood pressure in a standing or lying position. It has been proven that the administration of this drug at therapeutic doses (i.e., 1 or 2 mg per day) is effective in the treatment of mild and mild arterial hypertension.

According to experts, the effect of this remedy is maintained throughout the day. Moreover, it is especially effective during physical exertion.

Long-term use of the drug does not cause addiction.

Properties of the preparation

What is remarkable about such a tool as "Albarel"? Instructions for use, reviews of experts say that taking this medication in therapeutic doses does not affect the work of the heart, and does not cause water and sodium retention in the body and does not disturb the metabolic balance.

This drug reduces OPSS without any changes in cardiac output. It should also be noted that the electrophysiological indices and contractility of the myocardium against the background of taking this medication remain unchanged.

The antihypertensive agent under consideration does not cause orthostatic hypotension (including the elderly), does not affect renal blood flow, does not disrupt the physiological response (compensatory) of the heart rhythm to exercise, nor does it affect fat and carbohydrate metabolism, filtration fraction and glomerular filtration.

Kinetics

Are Albarel tablets absorbed? Instruction for use asserts that the said drug is completely and very quickly absorbed from the intestine. After taking a single dose of the drug, its highest concentration in the plasma is observed after 2 hours.

Absolute bioavailability of the drug is 100%. It should also be noted that it is not subjected to the first passage through the liver.

The equilibrium state of the patient is established only from the 3rd day of regular intake of tablets. In people with hypertension who have been on treatment for several years, the concentration of the drug in the plasma remains stable.

This medication is excreted with human milk. His metabolites are found in urine only in trace amounts. The half-life of the drug is about 8 hours. This period does not change even with the repeated administration of tablets.

Indications

In what cases is the drug being prescribed to patients? What does the instruction for use say? "Albarel" is an antihypertensive drug that is actively used for arterial hypertension.

Prohibitions for appointment

Use of the drug "Albarel" is prohibited when:

• Pregnancy;
• Severe depression;
• Renal failure (severe);
• Breastfeeding;
• Hypersensitivity to rilmenidine or other components of the drug.

It should also be noted that this medicine is not used in pediatric practice.

"Albarel" tablets: instructions for use

Treatment with this medication should be started only after consultation with the doctor. If the patient does not have access to a doctor, carefully read the instructions before taking the medication. According to her, to achieve the desired effect, the patient should take one tablet before breakfast. If such a dosage of "Albarela" did not improve the patient's condition, then it is increased to 2 tablets per day (take on the eve of breakfast and dinner).

The treatment is long-term.

Although the withdrawal of this medication usually does not cause side effects, discontinuation of therapy should occur gradually, with a smooth dose reduction.

Side effects

What adverse reactions causes the antihypertensive drug under consideration? What does the instruction for use confirm? "Albarel" can provoke such undesirable phenomena as:

• Heart beat, orthostatic hypotension, cold extremities effect (in single cases);
• Asthenia, increased fatigue when performing physical exercises, drowsiness, anxiety, insomnia or depression, convulsions (in isolated cases);
• Nausea, epigastric pain, constipation, dry mouth, diarrhea;
• Itching, skin rash.

It should also be noted that against the background of taking this medication, some patients experienced peripheral edema, hot flashes and disorders of sexual function.

An overdose means

What happens when you use a lot of "Albarel" tablets? Instructions for use, the doses of this remedy were presented above. If the latter is exceeded, the patient may develop severe arterial hypotension and various disorders in the psyche. In this case, the victim is prescribed gastric lavage and conducts sympathomimetic therapy.

Interaction with other drugs

It is highly not recommended to take tablets "Albarel" with alcoholic beverages and MAO inhibitors. Also, the following manifestations of the drug interaction of the drug were detected by the specialists:

• With diuretics, vasodilators and antihistamines, the effect of the drug is potentiated;
• With tricyclic antidepressants there is a decrease in the antihypertensive effect of the drug;
• With drugs that depress the effect of the central nervous system, there is an increase in drowsiness.

Special Information

If the drug is used by people who have recently suffered a stroke or a myocardial infarction, they need constant medical supervision.

In view of the good tolerability of the "Albarel" tablets, they can be prescribed for elderly patients, as well as for patients with diabetes mellitus.

If treatment is to be discontinued, the dosage of the drug should be reduced gradually. It should be remembered that in most cases, the abolition of the medication is not accompanied by any side effects.

It is forbidden to prescribe Albarel at the same time as MAO inhibitors and alcohol-containing products.

Clinical information about the effectiveness and safety of the drug in children and juveniles is not enough. In this regard, this drug should not be assigned to this category of patients.

In therapeutic doses, "Albarel" does not have any effect on the psychomotor reactions of a person. If the drug was taken in large quantities or along with drugs depressing the central nervous system, in this case, the patient is forbidden to sit behind the wheel of vehicles, as well as engage in other hazardous activities.

Analogues and reviews

There are not many analogues in this preparation. Among the most accessible and most popular one can mention "Tenaksum". This medication is also an antihypertensive agent belonging to the oxazoline group. It has a similar list of contraindications and side reactions, however it is more expensive.

As for the patients' opinions about this drug, they are few. Like doctors, consumers argue that this is a very effective tool designed to eliminate hypertension. Also, the advantages of the drug include its long-term therapeutic effect, including physical exertion.