"Catadolon" preparation: instructions for use

The drug "Catadolone" is a drug that is used to relieve the symptoms of pain. Painful sensations can arise with neuralgia, neuritis, degenerative diseases of joints, oncological diseases, migraine, spasms of musculature of the motor apparatus, bruises, chemical, thermal burns. The drug belongs to the non-opioid analgesics of the central action.

The drug "Catadolone". Instructions for use: dosage form, composition

The medicinal substance is released in the form of capsules, which have a brownish-orange color. They contain a white powder that does not smell. "Catadolone" - tablets are much less common, as they have a somewhat reduced pharmacological effectiveness, an increased period of clinical action.

The main active substance of the drug is flupirtine maleate. The auxiliary components include calcium phosphate dihydrate , capovidone, magnesium stearate, red iron oxide , titanium dioxide, purified water, sodium lauryl sulfate, gelatin.

Capsules "Catadolone". Instructions for use: pharmacokinetics, pharmacodynamics

The active substance of the preparation after oral administration is rapidly absorbed (bioavailability reaches 90%). Flupirtine is metabolized in the hepatic tissue. As a result of chemical transformations, urethane structures are formed, metabolites M1, M2. Most of the drug is excreted by the kidneys. The half-life reaches seven hours, which is the most optimal value for analgesics. When the drug is administered to elderly patients, an increase in this indicator is observed.

The active substance of the drug is a prototype of a class of non-selective substances that activate specific potassium channels. The active substance has analgesic, myorelaxing, neuroprotective effects.

Medicinal product "Catadolone". Instructions for use: dosage

The dose of the drug is selected depending on the individual sensitivity of the patient, the severity of the pain symptom. It is necessary to take one capsule four times a day, washing them with plenty of water. In severe, intense pain, the dose may increase to two capsules per reception. Take should be three times during the day. For elderly patients, this value should be reduced due to a decrease in metabolic functions. The daily intake of the drug should not be more than six capsules, otherwise an overdose will occur. In fairly rare cases, the capsule can be opened and taken through a probe.

Medicinal product "Catadolone". Instructions for use: side effects, contraindications

Among the side effects of the drug are weakness, dizziness, nausea, vomiting, dizziness, diarrhea, abdominal pain, flatulence, anorexia, depression, sleep disorders, tremor, confusion, sweating, allergic reactions (itching, urticaria, hyperthermia). In very rare cases, hepatitis can occur, which is accompanied by jaundice with the development of symptoms of cholestasis. When the first such symptoms appear, you should stop using the pharmaceutical agent "Catadolone". A description of all possible indications, contraindications, drug interactions is found in the instructions. Therefore, when buying a medicine you need to carefully study it.

There are the following contraindications to the use of the drug: liver cirrhosis, hepatic insufficiency, accompanied by encephalopathy, muscle asthenia, cholestasis, chronic alcoholism, lactation, pregnancy, hypersensitivity to individual components.