Analogues "Combiblox" and reviews about them

An excellent preparation for combating parasites and microbes inhabiting the human body is the "Combiblox" medicine. The drug has a wide range of effects. Most often it is used in the presence of mixed infectious pathologies that are bacterial in nature. But some patients for various reasons can not resort to the help of the original remedy. Naturally, they have many questions. What kind of analogs can I take? "Combiflox" and its substitutes have the same efficiency? Let's understand.

Brief description of the drug "Combiflox"

The drug is an excellent antimicrobial and antiprotozoal drug with antibacterial activity. Combined medicine is prescribed for a variety of ailments of an infectious nature.

Its wide range of effects is dictated by the components that make up the drug:

1. Ornidazole. This substance has antimicrobial and antiprotozoal effects. The component is a 5-nitroimidazole derivative. The substance, getting into the human body, affects the DNA of pathogenic microorganisms. As a result, the bacteria die. The ingredient actively struggles with a variety of microorganisms. But to the aerobic remains insensitive.
2. Ofloxacin. Antimicrobial substance in the group of fluoroquinolones. Its mechanism of action is associated with the effect on DNA-gyrase (bacterial enzyme). The component ensures the destabilization of DNA chains. This effect leads to the death of bacteria. The substance has a pronounced bactericidal effect.

The preparation is produced in the form of tablets, top coated with a film membrane.

Indications for use

What is the medicine Combiblix? Instruction of the drug recommends taking the pill when:

1. Bacterial mixed infections, provoked by sensitive microorganisms.
2. Infectious-inflammatory diseases of the peritoneum, kidneys (pyelonephritis), bile ducts.
3. Irregularities in the reproductive system and pelvic organs (endometritis, oophoritis, salpingitis, cervicitis, parametritis, colpitis, orchitis, prostatitis, epididymitis).
4. Infectious diseases of the urinary canals (urethritis, cystitis).

Contraindications to admission

Before using this medication in therapy, it is necessary to carefully study the limitations on treatment.

"Combiflox" tablets - instructions for use prohibit people from using, under the following conditions and pathologies:

• Individual hypersensitivity;
• epilepsy;
• Age, less than 18 years;
• Reduced convulsive threshold (triggered by CCT, stroke, inflammation of the central nervous system);
• pregnancy;
• Defeat of tendons on the background of fluoroquinol therapy;
• Lactation period.

special instructions

With high caution the drug is prescribed for patients suffering:

• Atherosclerosis;
• Disorders of cerebral circulation;
• Renal insufficiency;
• Liver diseases;
• Organic pathology of the central nervous system (multiple sclerosis);
• Predisposition to convulsive manifestations;
• Myasthenia gravis;
• Diabetes mellitus;
• Ailments of the heart (heart attack, heart failure, bradycardia);
• Various mental disorders in the anamnesis;
• Alcoholism.

Side effects

The medicine can become a source of numerous unpleasant reactions. That is why the prescription of this medication should only be a doctor who will monitor the treatment process. So, with what reactions can the patients who use Combiblox tablets come across?

The instruction warns of the possible appearance of the following side effects:

1. Digestive system. Perhaps the emergence of gastralgia, nausea, vomiting. Sometimes the appetite decreases, there is diarrhea or constipation. Patients may experience abdominal pain, elevated flatulence, hepatitis, cholestatic jaundice, pseudomembranous colitis. Many complain of increased dryness of the oral cavity.
2. Nervous system. Therapy may be accompanied by dizziness, high nervousness, insomnia, headache. Sometimes there is a tremor, paresthesia or numbness of the limbs, convulsions, uncertainty in the movements. The patient may be tormented by nightmares. Some patients manifest phobias, depressions, hallucinations. Perhaps the emergence of epileptic seizures, psychotic disorders with predisposition to suicide.
3. Musculoskeletal system. It is impossible to exclude the risk of developing a patient tendosynovitis, tendonitis, arthralgia, myalgia. Sometimes during treatment, painful sensations appear in the limbs, muscle weakness, and tendon ruptures are diagnosed.
4. Sense organs. The patient may encounter a violation of taste, smell. Sometimes malfunctions arise with coordination or hearing. Some patients note a violation of color perception or strangeness in the taste sensations.
5. Heart system. Periodically, patients suffering from tachycardia. Some note an increase or, conversely, a decrease in pressure. Possible collapse, ventricular arrhythmia. Sometimes the QT interval elongates.
6. Allergy. Treatment can be accompanied by the appearance of hives, itching, an unpleasant skin rash. In some cases, there is a development of allergic pneumonitis, nephritis, angioedema, fever, bronchospasm, eosinophilia. Exudative erythema, epidermal toxic necrolysis, anaphylactic shock, photosensitivity, vasculitis can appear. Women may experience increased itching in the genital area.
7. Organs of hematopoiesis. During therapy, there is sometimes a development of leukopenia, anemia. Some face with thrombocytopenia, agranulocytosis.
8. Urinary system. Sometimes patients complain of impaired renal function, dysuria, urinary retention. On the background of treatment, urea concentration may increase, kidney failure may develop.

In addition to the above unpleasant manifestations, it is possible to appear:

• Intestinal dysbiosis;
• Superinfection;
• Hypoglycemia;
• Vaginitis;
• Pain in the chest;
• Increased fatigue;
• Nasal bleeding;
• Strong thirst;
• Pharyngitis;
• Rhinitis;
• Dry cough.

The best analogies

What drugs can replace the original remedy? On the pharmacological market, there are the following analogues of "Combiblox

»:

• "Ashof" (solution);
• "Danzil" (drops);
• "Gairo" (tablets);
• "Zanotsin" (solution, tablets);
• "Dazolik" (tablets);
• "Zofloks" (solution, tablets);
• Ornidazole (tablets);
• "Lornisol" (pills);
• Ornion (tablets);
• "Oflo" (pills);
• Ornisid (tablets);
• "Ofloxabol" (solution);
• "Ofloks" (tablets);
• "Ofloxacin" (tablets, solution, ointment);
• "Tarium" (solution);
• Taricin (tablets);
• "Tiberal" (pills);
• "Floxal" (drops, ointment);
• Uniflox (drops).

The list of drugs that can become an alternative to the original medication is quite extensive. However, you should not choose analogues of "Combiflox" yourself. Before you replace a medication you should consult a doctor to avoid the occurrence of extremely negative reactions.

How else can I replace the original medicine?

Do you need to find the closest analogue to the medicine? "Combiflox" tablets can be replaced with drugs: "Ofloxacin" (200 mg) and "Ornidazole" (500 mg). It is these drugs that are the active ingredients of the original remedy.

These drugs must be taken together. Sometimes they are advised to separate in time. To properly draw up a therapy scheme (if these analogues are chosen "Combiflox"), it is necessary to consult with the attending physician.

Patient's opinion

How do people respond to treatment with KombiFlex? Patients' testimonies indicate that some unpleasant reactions do appear during therapy. Most patients suffer from nausea, dizziness. Often, patients indicate the appearance of mental disorders, worsening mood.

The doctors explain the occurrence of such reactions by the high concentration of the two strongest antibiotics. In this case, doctors are not in a hurry to prescribe to the patient such a strong medication. As practice shows, "Combiblox" medication is used only in those situations when the long-term treatment undertaken did not provide positive results.

Can analogues become an effective alternative to the original medication? Unfortunately, in most cases - no. For example, the drug "Ofloxacin" affects only part of the pathogenic microflora. Therefore, in some diseases, the drug may not be effective. This feature is peculiar to the drug "Ornidazole".

Conclusion

Only in the right combination ofloxacin and ornidazole active substances can effectively rid the body of developing serious pathologies. That is why, despite a lot of negative symptoms, which manifests itself during therapy with the drug "Combiflox", patients indicate that the original medication does help.