"Vero-Amlodipine": instructions for use, reviews, analogues

Arterial hypertension is called persistent increase in blood pressure. In this state, the following indices are observed: 140/90 mm Hg. Art. and more.

Experts argue that hypertension is one of the most common diseases of the cardiovascular system. According to statistics, it affects about 20-30% of the total adult population. Moreover, with age, the prevalence of this disease is markedly increased and often reaches 50-65%.

Such a state can arise because of a variety of reasons. Most often hypertension develops because of psycho-emotional overstrain.

Specialists identify several risk factors for the spread of this disease. They include: age, sedentary lifestyle, sex, excessive consumption of table salt, hypocalcemic diet, alcohol abuse, heredity, smoking, obesity, diabetes mellitus and others.

To lower the raised or increased arterial pressure it is necessary. Otherwise, it can lead to disastrous consequences.

Most often in hypertension, doctors prescribe to their patients a drug such as "Vero-Amlodipine."

The instructions for use, testimonials, analogues and properties of the medicinal product will be presented below.

Composition, description, packaging, composition

The drug "Vero-Amlodipine" comes in the form of flat-cylindrical white tablets. The main component of this drug is amlodipine. It is presented in the form of besylate.

Tablets "Vero-Amlodipine" go on sale in contour cells (10 pieces), which are contained in a cardboard bundle.

Pharmacological characteristics of the drug

What is a tool like Vero-Amlodipine? Instruction for use indicates that this drug is able to have a pronounced antihypertensive and antianginal effect. It prevents the entry of Ca ions through the membranes into the cells of the myocardium and vessels.

Arterial pressure reduces this medication due to the ability to dilate blood vessels.

Antianginal effect of the drug is provided by its active substance. Specialists say that amlodipine is able not only to expand peripheral arterioles, but also contribute to the reduction in OPSS. However, it does not cause a reflex tachycardia.

Due to this influence, the heart muscle begins to consume less energy, and also significantly reduce the need for myocardium in oxygen.

It should also be noted that when a spasm of the coronary arteries occurs, the drug in question contributes to the increase in the delivery of oxygen to virtually all zones of the myocardium.

Kinetic Properties

What kinetic properties are characteristic for the tablets "Vero-Amlodipine"? Instructions for use informs you that when you take the medicine inside, it is slowly, but almost completely absorbed from the digestive tract.

The peak concentration of this drug in the blood is reached within 8-9 hours. The binding with plasma proteins is about 97-98%.

This drug undergoes minimal metabolism, forming derivatives with little pharmacological activity. This happens when you first pass through the liver.

The average half-life of the drug is 35 hours. With arterial hypertension, this period can be increased to 48 hours, in the elderly - up to 65 hours, and with impaired liver function - up to 60 hours.

This medication is excreted primarily in the form of metabolites through the kidneys (about 58-62%) and through the intestine (about 20-27%).

Indications for taking medication

In what cases are the tablets "Vero-Amlodipine" appointed? Indications for use of this tool are as follows:

• Vasospasm or vasoconstriction;
• Arterial hypertension (in the form of monotherapy, and also together with other medicines);
• Stable angina;
• Vasospastic angina pectoris;
• Dilated cardiomyopathy (non-ischemic) with stage 3-4 heart failure (chronic).

One can not help saying that the medicine in question can be prescribed in the form of monotherapy. It is also often used in conjunction with antianginal drugs (prescribed to people who are not susceptible to nitrate therapy or beta-blockers).

Contraindications to taking tablets

When can I not prescribe the drug "Vero-Amlodipine"? The use of this drug is prohibited with arterial hypotension. Also, the drug in question is not prescribed to minors and in the presence of hypersensitivity to amlodipine or other dihydropyridines.

Medication "Vero-Amlodipine": instructions for use

This medication is for oral use only. Its dosage is determined by the attending physician, depending on the patient's condition.

For people with angina or hypertension, the minimum daily dose is 5 mg. In the future (with the urgent need), the indicated amount of the drug can be increased to 10 mg a day.

In the presence of dilated cardiomyopathy, it is advisable to start therapy with a dosage equal to 2.5 mg. Later (with the normal tolerability of the drug), this dose can be increased to 10 mg.

According to the instruction, exceeding the indicated amount of the drug (10 mg per day) is highly discouraged. This is due to the fact that it is the maximum permissible.

Simultaneous reception of the drug "Vero-Amlodipine" with beta-adrenoblockers, as well as ACE inhibitors and thiazide diuretics does not require dose adjustment.

Side effects

The drug "Vero-Amlodipine", reviews about which are always positive, in rare cases can cause (in case of non-compliance with dosages):

• Gingival hyperplasia, nausea and abdominal pain;
• Tachycardia, flushing, arrhythmia, palpitations, dyspnea, peripheral edema, arterial hypotension;
• Paresthesia, fatigue, drowsiness, headache, dizziness;
• Rash, itching.

One can not help saying that with prolonged intake of "Vero-Amlodipine" tablets, the patient may have severe pain in the limbs.

An overdose of a drug

What will happen if you significantly exceed the dose of Vero-Amlodipine? Instructions for use do not provide any information about symptoms of overdose. Although experts argue that in this case there are pronounced adverse reactions.

Interaction with other drugs

Can I take with other drugs tablets "Vero-Amlodipine" (from which this drug is prescribed, we told above)?

The hypotensive effect of this drug is enhanced by its combination with calcium channel blockers. The same result can be expected with a medication intended for inhalation anesthesia, as well as orlistat. Moreover, such combinations can provoke a sharp increase in pressure and hypertensive crisis.

The sodium retention in the patient's body and, as a consequence, the decrease in antihypertensive effect is observed with the use of amlodimipine with sympathomimetics and estrogens. To strengthen these properties, you must simultaneously take "Quinidine" or "Amiodarone."

The appearance of such signs of neurotoxicity as nausea, tinnitus, vomiting, ataxia and diarrhea can be caused by simultaneous reception of "Vero-Amlodipine" and lithium carbonate.

The combination of the drug in question with indomethacin or other NSAIDs often leads to a reduction in its antihypertensive effect.

Breastfeeding and Pregnancy

Is it possible to take Vera-Amlodipine medication during pregnancy, the analogues of which are listed below? According to experts, the safety of this medication during the period of gestation is not studied. The same applies to breastfeeding. Therefore, prescribe this drug under such conditions should be only if the risk to the baby is much less than the health benefits of the mother.

Special recommendations for taking tablets

What should the patient know before taking this medication? According to the instructions, this remedy is especially prescribed for stenosis of the aortic aorta and the disturbed work of the kidneys and liver.

Adjustment of the above dose to the elderly is not required.

The drug "Vero-Amlodipine" can be used to treat patients with dilated cardiomyopathy (non-ischemic) accompanied by heart failure (chronic).

There are no clinical data on the use of this drug in pediatric practice.

The term of the drug sale, its storage and sale conditions

Contain this medication preferably in a dry and dark place, where there is no access for small children, and where the air temperature does not exceed 26 degrees.

This drug is dispensed in pharmacies without a prescription. The term of its implementation is two years. After this period, take pills is prohibited.

Cost and similar means

About how much is the drug "Vero-Amlodipine", you can find out only in the pharmacy. As a rule, its price depends on the number of tablets in the package and the dosage. 10 mg of the drug cost about 57 rubles, and 5 mg - 30 rubles.

As for the analogs, there are quite a few of them. According to specialists, antihypertensive properties are inherent in the following medicines: Agen, Acridipine, Adipin, Amlo, Amlodipine Sandoz, Amlodipine, Amlodipine Teva, Amlodak, Amlovas, Amlodigamma , Amlodipine Alkaloid, Amlodil, Amlodipine Zentiva, Amlodipine-Aggio, Amlodipine Cardio, Amlodipina Bezilat, Amlocard-Sanovel, Amlodifarm, Amlong, Amrorus, Amlotop, Amlonorm, Calchek, Karmagip, Cardilopin, Corvadil, Norvadin, Cordy Cor, Norvasc, Omelar Cardio, Normodipin, Stamlo, Stamlo M, C Tamlo M, Tenox.

What is the difference between "Amlodipine" and "Vero-Amlodipine"?

It is rather difficult to answer the question unequivocally. After all, both mentioned preparations contain the same active substance in identical doses.

According to experts' opinions, these funds are distinguished only by the fact that they were issued by different pharmaceutical companies. Accordingly, the production technology of "Amlodipin" and "Vero-Amlodipina" is different.

It is not possible to talk about greater efficacy of this or that remedy, since they have the same effect and are called upon to lower the increased pressure.

Also it should be noted that these drugs can have different prices.

Consumer reviews and reports from doctors

With age, arterial hypertension is affecting more and more people. This disease is characterized by severe headaches, dizziness, darkening in the eyes, weakness, excessive fatigue and so on. As a rule, all of these symptoms disappear within a few hours after taking the medication in question.

Doctors say that the drug "Vero-Amlodipine" is one of the most effective and quick-acting means. In a short period of time, he normalizes blood pressure, significantly improving the patient's condition.

Among the merits of this drug many note its convenient form and method of application. To lower the pressure, you only need to take one tablet a day. At the same time, experts warn that exceeding the recommended dose may lead to the occurrence of adverse reactions. Therefore, more than 10 mg of the drug per day is not necessary.

Also it should be noted that very few patients are pleased with the small cost of the said product, its availability and the ability to replace with analogues of other manufacturers.