The preparation "Baconase": the instruction, analogues and responses

Allergic reactions disturb many people. To get rid of such manifestations, doctors recommend using special anti-allergic drugs that significantly improve the patient's condition and eliminate all unpleasant symptoms.

In this article, we will tell you about how a medication such as "Baconase" works. Instructions for using this local tool will also be provided below.

Form of issue, composition, packaging

The preparation "Baconase", the instruction of which is enclosed in a cardboard bundle, is made in the form of a water spray for nasal application. Beclomethasone dipropionate is an active component of this agent.

The drug is sold in vials with a special dispenser.

Pharmacology of a local remedy

What is the "Baconase" spray, the analogues of which are indicated below? This medication is an intranasal form of a topical glucocorticoid that has anti-edematous, anti-inflammatory and anti-allergic properties.

Details about the properties of the medicament

The antiallergic effect of the drug in question is due to its ability to suppress the susceptibility of receptors to active biological substances (histamines, prostaglandins) and mechanical stimuli. In other words, this agent has a direct effect on their nonspecific hyperreactivity.

The drug contributes to the inhibition of degranulation of mast cells, and also removes all active manifestations of allergic inflammatory processes. He also restores the sense of smell. It is this property that distinguishes the drug "Baconase" (spray) from other agents against allergies.

The agent under consideration improves mucociliary transport and does not affect neutrophils. In this regard, the drug does not change the immune response to a bacterial infection.

The anti-inflammatory properties of "Baconase" are explained by its effect on cells by excitation of receptors that are responsible in DNA for the transcription of target genes that regulate the synthesis of protein molecules involved in inflammation.

According to experts, this drug is able to inhibit the induction of synthesis of nitric oxide, the activation of which has a pronounced pro-inflammatory effect. It also inhibits the synthesis of pro-inflammatory cytokines, which provoke the inflammatory process.

It should also be noted that after the application of the spray, IgE production and the formation of leukotrienes in the mucous membranes are blocked. Medication has a depressing effect on the activity of genes that regulate the synthesis of enzymes and other protein molecules that participate in the allergic process. As a result of this influence, tissue edema decreases and a decrease in glandular secretion in the mucosa is observed.

Pharmacokinetics of the drug

Is the drug "Baconaze" absorbed? The instruction says that the drug is absorbed rather quickly into the nasal mucosa. About 5% of the used dose goes into the blood. In this case the drug is completely biotransformed at the first passage through the liver.

The very low bioavailability of this drug reduces the likelihood of undesirable effects to a minimum, even with prolonged use.

The drug comes into contact with albumin by 80-90%. Its half-life is 16 hours. Eliminates the medication by the kidneys and along with the feces.

Indications

For what purpose do nasal drops of "Baconase" are prescribed? According to experts, this drug is used in inflammatory processes of non-infectious genesis, which occur in the nasal cavity. Also it is used for relapses of nasal polyposis and allergic rhinitis (seasonal or year-round).

Contraindications

When should you not use the spray "Baconase"? The doctors' comments say that this remedy has a rather large number of contraindications. It is not recommended for use with beclomethasone intolerance, as well as in such conditions as:

• Glaucoma, myocardial infarction in anamnesis, pathology of the renal system;
• Amoebiasis, herpes mucous eyes;
• Tuberculosis of the lungs, recent trauma and operation on the nose;
• Systemic infections of fungal or bacterial origin, hypothyroidism, ulceration of the septum of the nose;
• Breast feeding, pregnancy.

The preparation "Baconase": the instruction

The medicament in question is administered for intranasal administration only. In the children's age group of 6 years, as well as adults, the drug is recommended to use in the amount of one dose in each half of the nasal cavity. To instillation should be three or four times a day. If a double dose of medication is used, it is injected twice a day.

As practice shows, the therapeutic effect after application of the spray is noted after 5-7 days.

Adverse events

The drug "Baconase", the price of which is listed below, is absolutely safe for adult children, even with prolonged use. Its systemic adverse reactions are insignificant.

In rare cases, the medication can cause local unwanted reactions in the form of sneezing, burning and dryness of the nasal mucosa, as well as bleeding and recurrence of herpetic infection. In addition, perforation of the septum of the nose was noted in single cases.

In the presence of hypersensitivity, the patient may develop such allergic reactions as hives and skin rashes.

Spray "Baconase": analogues and cost

If necessary, the drug "Baconase" can be replaced by such analogous means as "Agistam", "Eczazolin", "Otritin", "Marimer", "Kamphomene", "Physiomer".

Buy the drug "Baconaz" in the form of a spray will not be difficult, since it is sold in virtually all pharmacies without a doctor's prescription. Its cost varies between 800-950 rubles.

Reviews about the drug

The patients' comments on the preparation under consideration for local application are very ambiguous. Someone claims that it copes quite effectively with the task at hand and eliminates all signs of allergic rhinitis, as well as inflammatory processes in the nasal cavity of non-infectious origin.

However, there is also a category of people who report that this drug is absolutely useless. Moreover, a large number of patients quite strongly embarrass the cost of this medication. Although experts say that its price is fully consistent with quality.

The only positive aspect of this remedy, which is spoken by absolutely all patients, is that it very rarely causes side effects.