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The drug "Terbinafine" (ointment from nail fungus): reviews, instruction

Is Terbinafine effective (ointment from nail fungus)? Reviews of specialists and those who have ever used this medication will be presented at the end of the article. From it you will learn about what components are part of the said tool, how it should be applied to the affected areas, whether it has contraindications and so on.

Composition, packaging and description of the preparation

What substances contain the drug "Terbinafine" (ointment from the fungus of nails)? The instruction says that the active element of this drug is terbinafine hydrochloride. It also contains auxiliary ingredients in the form of paraffin, cetostearyl alcohol, glycerol, purified water, cetomacrogol 1000, propylene glycol, dimethicone, benzyl alcohol, poloxamer.

In what packaging can I buy a drug "Terbinafine"? Ointment from the fungus of nails is placed in aluminum tubes or cans of orange glass, which are contained in a cardboard bundle.

Pharmacological characteristics

What is a local remedy like Terbinafine (ointment from nail fungus)? Experts say that this is an antifungal drug that has a wide range of antifungal effects.

Applying even a small amount of medicament, it can have a fungicidal action against certain dimorphic and mold fungi, as well as dermatophytes. With regard to yeast fungi, the activity of the drug with respect to them depends on the species (for example, it can exhibit fungistatic or fungicidal activity).

Operating principle

How does Terbinafine medication work (ointment from nail fungus)? The use of this drug helps to change the early stage of the biological synthesis of sterols in fungi. This effect leads to intracellular accumulation of squalene, as well as a lack of ergosterol, which, in fact, causes the death of harmful cells.

The action of the agent in question is carried out by inhibiting the enzyme squalene epoxidase, which are located on the cell membrane of the fungus. It should also be noted that the ointment "Terbinafine" has no effect on the cytochrome P450 system and, accordingly, on the metabolism of other drugs and hormones.

Pharmacokinetics of a local drug

Is the drug "Terbinafine" (ointment from the nail fungus) absorbed? Experts say that after applying this drug to the skin, a transparent film is formed. From it, the drug is absorbed into the blood. Absorption of the medicament from the skin is minimal and is no more than 5% of the total dose.

Indications for use

Does the drug Terbinafine help the nail fungus? The doctors say that this medicine is really very effective in combating various kinds of fungi. According to the instruction, the agent in question is assigned at:

  • Yeast infections of the skin that were caused by the genus Candida (in particular, intertrigo);
  • Multi-colored deprive.

It should also be noted that the terbinafine ointment is used for the prophylaxis and tolerance of fungal infections of the skin, inguinal epidermophytosis, foot mycoses, fungal lesions of smooth integuments that were caused by dermatophytes.

Contraindications

Is there a contraindication to the use of the drug "Terbinafine" (ointment from the fungus of nails)? The feedback from experts indicates only one ban:

  • The patient's sensitivity to the active ingredient or to any of the auxiliary ingredients.

It should also be noted that with special care this medication is prescribed for alcoholism, hepatic insufficiency, tumor, metabolic disease, renal insufficiency, oppression of bone marrow hematopoiesis, in children under 12 years of age, and in occlusive vascular diseases of the extremities.

How to use Terbinafine (ointment) with nail fungus?

Reviews about this product will be presented below.

Adults and children from 12 years of age are prescribed medicines externally. Before it is applied, the affected areas are cleaned and dried. Ointment is used twice a day. Its thin layer is applied to the affected skin, as well as areas adjacent to it (lightly rubbed).

For infectious diseases, which are accompanied by intertrigo (for example, in the interdigital spaces, under the mammary glands, in the groin and between the buttocks), it is recommended to cover the application site with a gauze bandage (especially at night).

The average duration of therapy for trunk, foot and drumstick dermatomycosis is one week (once a day). When skin candidiasis ointment should be used 1-2 weeks twice a day. Treatment of colorful lichen is carried out two weeks twice a day.

The therapeutic effectiveness of the drug is already observed in the first days of treatment. With irregular therapy or its premature termination there is a big risk of renewal of the infection. If after 2 weeks signs of improvement are not observed, it is necessary to verify the diagnosis.

Side effects

Now you know how the treatment of the nail fungus "Terbinafine" is carried out. Experts say that side effects from the use of this drug are extremely rare. In view of the fact that the ointment is used only externally, undesirable reactions appear only externally. In most cases, they are reduced to itching, redness of the skin and burning in the place of application. Sometimes allergic reactions may develop.

Cases of overdose

To date, cases of overdose with the drug in question have not been recorded. However, experts say that if you randomly take the ointment inside, you can expect the same side effects as with an overdose of tablets (nausea, headache, stomach pain and dizziness).

As a treatment, the patient is given activated charcoal.

Lactation and the period of gestation

During the experimental studies of teratogenic properties, Terbinafine was not detected. It should also be noted that until today no fetal pathology has been reported in the application of the drug in question. However, doctors do not recommend the use of ointment during pregnancy. It can be prescribed only in extreme cases, according to strict indications.

According to the instructions, the drug "Terbinafine" is able to excrete together with breast milk. But with the application of the ointment, it is absorbed through the skin in minimal amounts. Therefore, negative impact on the baby is unlikely.

Special recommendations for the use of ointment

Before using Terbinafine, you should be aware that a decrease in the severity of clinical symptoms is usually observed in the first days of therapy. If the ointment was used irregularly or its use was interrupted due to a number of reasons, that is a high risk of recurrence of the infection.

This medication is intended for external application only. Therefore, avoid contact with eyes. Otherwise, it can cause severe irritation.

If the ointment is still on the mucous membranes, they should be rinsed immediately with warm water. If irritation develops, consult a doctor. If against the background of the use of this drug there were allergic reactions, then it must be canceled.

Price and analogy

What can replace the terbinafine ointment? Analogues for this form of the drug is not very much. The most popular is the gel "Lamizil". As for other forms, they include the following means: Atifin, Termikon, Lamifen, Exifin, Terbizil, Fungoterbin, Mycofin, Terbinox, Binafin, Lamikon »,« Fungotec ».

As for the price, the medicine under consideration is not very high. Buy an ointment in the amount of 15 g you can for 60-70 rubles.

Reviews of the local product

The drug "Terbinafine" has a fairly good reputation. This is due to the fact that in the overwhelming majority it completely cures the patient of the fungus. Proper use of the ointment, as well as a full course of treatment, help get rid of the problem in the shortest possible time.

However, the effectiveness and safety of the drug "Terbinafine" are far from the only reasons for its acquisition as an antifungal agent. Patients report that the main advantages of this medication are its availability, low price, the absence of strict contraindications and side effects.

Experts hold the same opinion, and therefore believe that the drug in question is an antifungal agent № 1 in Russia.

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