The drug "Ceftriaxone" (injections)

The drug "Ceftriaxone" (a form of production - a powder for the preparation of a solution) belongs to the category of semi-synthetic antibiotics of the third generation. The drug has a bactericidal effect, provoked by inhibition of synthesis in the cell wall of the pathogen. The drug is characterized by a fairly broad spectrum of action. Thus, the drug is active against gram-positive and gram-negative microorganisms. The drug is resistant to the effects of beta-lactamases.

Indications

The drug "Ceftriaxone" (injections) is prescribed for sepsis, meningitis, wound infections. The drug is recommended for infections in bones and joints, ENT organs, urinary tract and kidneys, soft tissues and on the skin. It is also shown as a prophylaxis for infections after surgery. Indications include gonorrhea, infections of the genitals, respiratory tract, pelvic organs, abdominal cavity.

Mode of application. Dosage The injection of "Ceftriaxone" is given intramuscularly or injected into the vein. Patients from the age of twelve recommend one to two grams per day. In cases of severe course of the pathology, dosage can be increased to four grams. For children weighing more than fifty kilograms, doses are prescribed, as in adults. Patients under twelve years of age, including infants, are recommended to have twenty or eighty milligrams per kilogram of body weight. In a day for newborns, the dosage should not be more than 50 mg / kg of body weight. The duration of the use of the drug "Ceftriaxone" (injections) depends on the nature of the disease. After completion of the main treatment and confirming the absence of an agent in the body and normalizing the temperature, it is recommended to administer the medication for another two or three days. Dissolution of the powder is carried out in a ratio of one gram to three and a half milliliters of water for injection. The drug "Ceftriaxone" (injections) is injected into the buttock, not more than one gram in one place. Reduce the pain can be used when injecting a 1% solution of "Lidocaine".

Adverse Reactions

Against the background of the use of the drug is likely the development of dyspeptic phenomena. In particular, patients develop diarrhea, vomiting, constipation, nausea, a taste disorder. In addition, the drug can cause pseudomembranous enterocolitis, dysbacteriosis, anemia, thrombocytopenia, leukocytosis. In some cases, a violation of kidney function, oliguria, anuria, erythema (multiforme), serum sickness, fever, bronchospasm, urticaria may develop. In rare cases, anaphylactic shock is noted . To adverse reactions also include nasal bleeding, superinfection, candidiasis.

Contraindications

The drug is not prescribed in the period of gestation, with hypersensitivity to cephalosporins, penicillins. The medication is not prescribed during lactation. Contraindicated "Ceftriaxone" (injections) premature and newborn children with hyperbilirubinemia, people suffering from enteritis and colitis, provoked by antibiotic therapy, as well as in the disorder of kidney and liver.