The drug "Anaprilin" - from what? The action of the medicine Anaprilin

Quite often, doctors prescribe to their patients the drug Anaprilin. What helps it get rid of? What is it like? Is there any contraindication to taking this medicine? These questions are of interest to many patients.

"Anaprilin" preparation: formulation and composition

For today the medicine is issued in the form of small tablets, but there is also a solution for injections, which, however, is used much less often.

The main active substance of the drug is propranolol hydrochloride. Each tablet contains either 10 or 40 mg of this component. Of course, the production also uses auxiliary substances: colloidal silicon dioxide, talc, calcium stearate, corn starch, and microcrystalline cellulose.

Pharmacological properties of the drug

This drug is a beta-blocker of indiscriminate action. The active component of this drug weakens the effect of sympathetic pulses on myocardial beta receptors. Thus, there is a decrease in the frequency and strength of cardiac contractions, as well as neutralization of the effects of catecholamines. The drug reduces the need for cardiac muscle in oxygen. Under his influence, there is a decrease in blood pressure.

But on this action "Anaprilina" does not end. For example, immediately after taking the medication, the tonus of the bronchial muscles, as well as the contractile capacity of the uterus, increases. In addition, there is an increase in motor and secretory activity of the digestive system.

After taking the pill quickly dissolves in the digestive tract, after which the active components enter the blood. The maximum concentration of propranolol is observed after 1-1,5 hours after administration. The medicine is excreted in the form of metabolites by the kidneys. The half-life is 3-5 hours. Only with prolonged use the substance can be stored in the blood up to 12 hours.

Indications for admission

Of course, today many patients are prescribed the drug Anaprilin. What helps this tool? To begin with, it should be noted that the main indication for its reception are diseases of the cardiovascular system, accompanied by an increase in blood pressure. For example, it is prescribed for people suffering from chronic arterial hypertension, as well as ciliary and sinus tachycardia.

In some cases, the drug is used for mitral valve prolapse, as well as neurocirculatory dystonia, hypertrophic cardiomyopathy and myocardial infarction.

There are other cases in which the drug "Anaprilin" is used. What else does he help with? Sometimes the medicine becomes an excellent prevention of severe migraine attacks. In combination with other drugs, it is used for the treatment of abstinence syndrome. It is also known that the treatment of hemangioma with "Anaprilin" is also often successful, and at the initial stages even helps to avoid surgical intervention. And although the drug was not developed for this purpose, in modern surgery it is often prescribed even to children.

Tablets Anaprilin: instructions for use

Tablets are best taken 10-30 minutes before meals, preferably with plenty of liquid. Immediately it is worth noting that only the attending physician can prescribe to you the drug "Anaprilin". The dose here is determined individually.

As a rule, the reception starts with 10 mg of propranolol per day. If the medicine is transferred well, the daily amount is gradually increased to 80-100 mg, divided into four doses. In some cases (if the drug does not cause adverse reactions, and the therapeutic effect is poorly expressed), the dose may be increased to 180-300 mg divided into 4-6 receptions.

Duration of therapy is also determined separately for each patient, but, as a rule, the course of treatment is 3-4 weeks. In some cases, doctors recommend that you take a break for two months, then repeat it again.

If it is an arrhythmia or ischemic disease, then beta-blockers take much longer. But in this case, it is extremely important to gradually stop the medicine. If you stop abruptly, serious and dangerous complications are possible.

Contraindications for treatment

Of course, in this case, therapy has some contraindications. In particular, the drug is not used to treat patients with complete or partial atrioventricular or sinoatrial blockade. In addition, a contraindication to admission is sinus bradycardia, in which the frequency of cardiac contractions does not exceed 50 beats per minute. The medicine can not be given to patients suffering from hypotension.

The drug is contraindicated in people with certain diseases of the respiratory system. For example, it should not be taken to patients with severe bronchial asthma, as well as people with a tendency to bronchospasm. Contraindications are also obliterating peripheral vascular diseases, as well as Raynaud's syndrome and diabetes mellitus.

Are there any side effects?

In fact, there are a number of violations that may appear against the background of taking the drug Anaprilin. What is it worth to insure against? What to look for? Most often, the medicine causes frustration on the part of the digestive system. For example, some patients complain of severe nausea, which is often accompanied by vomiting, as well as pain in the epigastric region. Diarrhea is also possible. Much less common are more serious side effects, including various violations of the liver, as well as ischemic colitis.

Occasionally there are allergic reactions, accompanied by itching, redness and hives. In some cases, against the background of therapy, there is an exacerbation of psoriasis, as well as alopecia. Taking the drug may cause malfunction in the respiratory system, including bronchospasm, laryngospasm, and severe cough and shortness of breath.

From the side of the circulatory system, there are possible side effects such as bradycardia and arterial hypotension. In addition, the drug can affect the work of the nervous system, causing a sense of anxiety, insomnia and nightmares. There may be headaches, dizziness. Much less often patients develop clinical depression.

The drug "Anaprilin": an overdose, its symptoms and methods of treatment

Taking too much of the medication can affect the performance of the entire body. In particular, the symptoms include severe dizziness and weakness. Often there is a marked decrease in blood pressure, as well as arrhythmia, bradycardia and other disorders of the circulatory system until the development of heart failure.

There are other disorders, which can lead to the reception of a large amount of the drug Anaprilin. Overdose can be accompanied by difficulty breathing, bronchospasm. Sometimes there is convulsions and collapse.

A person with such symptoms should be rushed to the emergency department. If possible, induce vomiting. As a first aid, doctors perform gastric lavage and prescribe adsorption agents to patients. Further treatment directly depends on how much damage has been done. For example, with heart failure glycosides are used, and with convulsions, the drug "Diazepam" is shown.

Interaction with other medicinal products

The active components of this drug can interact with other medications. For example, the hypotensive properties of propranolol are enhanced by the simultaneous administration of anesthetics, sympatholytics, monoamine oxidase inhibitors and hydralazine. But the presence in the blood of hormonal drugs (in particular, estrogens and glucocorticosteroids), as well as non-steroidal anti-inflammatory substances, on the contrary, reduces the effect of taking Anaprilin tablets. With the introduction of radiopaque agents, the likelihood of developing anaphylactic reactions is significantly increased. Therefore, you must inform the doctor about all medications that you take.

Can I use the medicine during pregnancy?

Immediately it is worth noting that the use of the drug Anaprilina, as well as almost any other beta-blocker, during pregnancy is contraindicated. The fact that this drug reduces the level of placental perfusion, which in turn increases the risk of fetal death or premature birth. In some cases, the mother's intake of the drug leads to the development of bradycardia in the fetus. The probability of various complications in the postpartum period, in particular, from the respiratory and cardiovascular system, is high.

The doctor can prescribe to the pregnant patient this medicine only if the expected benefit for her exceeds the possible risk for the child. By the way, the main components of the drug can penetrate into breast milk, so the lactation period is also a contraindication.

Additional information about the preparation

Today, many people are interested in questions about what Anaprilin is, the instructions for use, the price, possible side effects. And immediately it is worth noting that experts categorically prohibit drinking alcohol during therapy. The fact is that alcohol together with tablets can lead to a dramatic life-threatening reduction in blood pressure.

Keep the drug in a dry, warm place, protected from direct sunlight at a temperature of no higher than 25 degrees Celsius.

As for the cost of the medicine, it ranges from 40 to 100 rubles. By the way, almost in any pharmacy you can buy tablets "Anaprilin", a prescription for a doctor is not needed. The drug also has analogues, in particular, the means "Inderal", "Propamin", "Stobetin" and some others.