Preparation "Gripgo": instructions for use, description, indications, composition and reviews

With the onset of winter cold everyone is at risk of catching an infection. To avoid such trouble, regular preventive measures should be taken to improve your health and the immune system as a whole.

Unfortunately, not everyone knows what actions need to be taken to protect themselves and their family members from colds and flu. Therefore, when changing seasons, very many people get sick.

At the first symptoms of a cold you should consult a therapist. The doctor must prescribe to the patient special antipyretic and analgesic drugs. They normalize the patient's body temperature and eliminate all signs of the disease.

One of the most effective remedies against cold and flu is the drug Gripgo. The instructions, the method of application, the composition of this medication are presented below.

Form of release, description, composition and packaging

What substances does the Gripgo drug contain? The instruction and the description of the preparation state that it contains caffeine, paracetamol, chloropheniramine maleate and phenylephrine hydrochloride.

In addition to the active ingredients, the medicament in question also contains additional constituents in the form of croscarmellose sodium, microcrystalline cellulose and magnesium stearate.

The preparation "Grippo", the instruction on which application will be considered below, is issued in the form of biconvex and capsule-shaped tablets of white color. They are packed in blisters or strips, which are placed in bundles of paper.

Pharmacology of medicine

What are Gripgo tablets? Instructions for use indicate that it is a combination drug, the effectiveness of which is due to the ingredients that make up its composition. Let's consider the properties of each of the components in more detail.

Paracetamol is called an analgetic-antipyretic. It has analgesic and antipyretic properties. The effect of paracetamol is related to its effect on the hypothalamic center of thermoregulation, as well as its ability to inhibit the synthesis of prostaglandins.

Caffeine is an alkaloid belonging to a group of methylxanthines. It is able to stimulate the vascular and respiratory centers, as well as improve the emotional and physical state of a person. Due to such properties, the treatment of infectious diseases significantly reduces the manifestations of asthenia. Also, caffeine improves the analgesic effect of paracetamol.

Chlorpheniramine maleate is a so-called antihistamine. It reduces allergic reactions in case of an infectious disease. This component competitively blocks H1-histamine receptors, eliminates the runny nose, aching eyes and itching in the nose.

Phenylephrine hydrochloride is a sympathomimetic agent. It reduces flushing and edema in the respiratory tract (in the upper sections) and sinuses. This helps improve nasal breathing.

It should also be noted that this component is capable of stimulating alpha-adrenergic receptors. This results in a decrease in the permeability of peripheral vessels and their narrowing, as a result of which the formation of a mucous secretion is markedly reduced.

Indications

From what patients are prescribed a drug such as "Gripgo"? Instructions for use (the indication of this remedy will be presented right now) indicates that this medication is intended for symptomatic treatment of influenza and other acute respiratory diseases that occur as a congestion of the nose, headache, fever, pain in the muscles and eyes, sinusitis, Sore throat, rhinitis and cough.

Contraindications

Are there any contraindications to Gripgo tablets? The instruction on the use of the medicine informs that there are a lot of prohibitions for this drug. Let's consider their list right now:

• Hyperbilirubinemia;
• Hepatic or renal insufficiency (expressed);
• Severe cardiovascular diseases;
• Hyperthyroidism, pheochromocytoma, thyrotoxicosis;
• Hypersensitivity to drug substances;
• Exacerbation of peptic ulcer disease in the digestive tract;
• Pyloroduodenal obstruction, gastric ulcer with stenosis;
• Lung diseases;
• Disorders of hematopoiesis, unstable angina, cardiovascular atherosclerosis expressed, anemia, acute myocardial infarction, severe leukopenia, bradycardia, severe cardiac conduction disorders, arrhythmias, cardiac decompensation, organic circulatory system damage, ischemic heart disease occurring in severe Form;
• glaucoma;
• Severe arterial hypertension, increased excitement, insomnia;
• epilepsy;
• Prostate adenoma with residual urine, acute urinary retention in prostatic hypertrophy, bladder obturation;
• Acute pancreatitis;
• diabetes;
• Deficiency of glucose-6-phosphate dehydrogenase;
• Lactation and pregnancy;
• Alcohol abuse, treatment with beta-blockers or tricyclic antidepressants, treatment with MAO inhibitors and two weeks after completion of their admission;
• Age up to 12 years;
• States characterized by sleep disturbances or increased excitation;
• Increased QT interval, congenital or prolonged use of drugs, increasing the QT-interval.

The drug "Gripgo": instructions for use

Description, the indications of this medication were presented above.

According to the instruction, considered tablets should be taken by adults and teenagers from 12 years old. Their dosage is 1 piece four times a day.

The maximum dose of the drug is 4 tablets per day. The duration of treatment is 3-5 days.

Adverse events

Can the drug "Gripgo" (tablets) cause undesirable reactions? Instruction for use reports that this agent often causes various side effects. Let's consider them right now:

• Angioedema, skin allergic reactions, anaphylactic shock;
• Rashes on the skin, itching, multiforme exudative erythema, urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis ;
• Visual disturbances, increased intraocular pressure, accommodation, dry eyes, mydriasis;
• Anxiety, dizziness, dyskinesia, headache, increased excitability, psychomotor agitation, tinnitus, a sense of fear, epileptic seizures, disorientation, behavior changes, irritability, convulsions, insomnia, coma, confusion, tremor, drowsiness, depressions, tingling And heaviness in the limbs;
• Aseptic pyuria, difficulty urination, nephrotoxicity (papillary and interstitial necrosis, renal colic), urinary retention;
• Vomiting, decreased appetite, nausea, hepatonecrosis, heartburn, dry mouth, diarrhea, constipation, epigastric discomfort, flatulence, liver dysfunction;
• Increase in the content of liver enzymes;
• Anemia, thrombocytosis, methemoglobinemia, sulfgemoglobinemia, neutrophilic leukocytosis, erythrocytopenia, hyperprothrombinemia;
• Tachycardia, reflex bradycardia, arterial hypertension, pain in the heart, myocardial dystrophy, dyspnea, heart palpitations, arrhythmia;
• Hypoglycemic coma, hypoglycaemia;
• Bronchospasm with allergies to NSAIDs and acetylsalicylic acid;
• Violation of the metabolism of copper and zinc;
• General weakness, increased sweating, hypoglycemia;
• Pancytopenia, neutropenia, aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia, the formation of cystine, oxalate and urate stones, the development of diabetes mellitus, pancreas damage, crystalluria (with long-term use of the drug and in large doses).

An overdose of a drug

What are the symptoms of an overdose of Gripgo? Instructions for use (the price of the medication is indicated below) informs that in this case the patient may experience: nausea, convulsions, vomiting, abdominal pain that appear after 1-2 days, visual impairment, toxic effects on the kidneys and liver (can cause Necrosis), coma, drowsiness followed by excitation, headache, arterial hypertension, circulatory disorders, bradycardia, dizziness, atropine-like psychosis, rapid breathing, extrasystole, trembling.

Treatment of overdose

To treat the above conditions, the patient is washed with the stomach, and also gives N-acetylcysteine (paracetamol antidote) and enterosorbent. In addition, the patient controls the functions of blood circulation and respiration.

Drug Interactions

Can I combine Gripgo with other medicines? Instructions for use suggest that the simultaneous use of this drug with hypnotics, analgesics and MAO inhibitors can enhance its inhibitory effect on the nervous system.

The combination of "Gripgo" with antidepressants, anticholinergic antispasmodics, angigistamines and antiparkinsonian drugs can cause an atropine-like effect, manifested by dry mouth, accommodation disorder, urinary retention and constipation.

With simultaneous reception with Procarbazine, sympathomimetics, thyroid hormones and Furazolidone, the likelihood of side effects increases.

When combined with nitrates, the effect of the latter is weakened.

It is forbidden to take Gripgo with other drugs that contain paracetamol, as well as with other NSAIDs and alcohol.

Special recommendations for taking medication

What do I need to know before using Gripgo tablets? Use in cases of impaired renal function (expressed) is prohibited. Also it should be noted that it is impossible to exceed the recommended dose and use the medication for more than five days in a row. In the evening, pills should be taken 3 hours before bedtime.

If the signs of the disease have not disappeared five days after the start of treatment, then it should be canceled and consult a doctor.

What other features does the drug Gripgo have? The instruction for use states that phenylephrine gives a false positive result in doping control.

During the treatment with the drug you can not use strong coffee, tea and other tonic drinks.

Abrupt withdrawal of the medicine can lead to depression of the nervous system with signs of depression and drowsiness.

With the long use of tablets, the development of mental dependence is possible.

Analogues and price of medicine

The drug under consideration (No. 100) costs about 750 rubles. If necessary, it can be replaced with drugs such as Adjikold, Antigrippin, Aksagripp, Antiflu, Vocasept, Apap, Gripout, Dolaren, Griposan, Dollar, Kold-N, Kaffetin, Koldreks, Lorkold, Kombigripp, Novalgin, Paralen Ekstra, Padeviks, Rinza, Spazgo, Solpadein, Flukoldeks, "Yunispaz", "Hitflu", "Gripex". The instructions, composition, application, analogues of these drugs can differ significantly from the drug we are considering. Therefore, appoint only an experienced doctor.

Customer Reviews

Now you know the properties of the drug "Gripgo". Instructions for use of this medication have been described in detail above.

According to consumers, this medication is very effective at high temperature, drowsiness, sore throat, joints and eyes, as well as asthenia during ARVI treatment. However, when taking this medication, do not forget about the many side effects that this drug can cause, including when the doses recommended by the doctor are not observed. In addition, the tablets "Gripgo" there is a huge number of different contraindications.