"Next": instructions for use. "Next": description, indications for use

Pain is one of the physiological phenomena that accompanies a person throughout life. It can be the result of bruises and injuries, spasms of muscles and vessels, irritation of nerve endings and a dozen different reasons. To combat the pain of modern man helps a lot of medicines. One such remedy is the tablets "Next", reviews about which in most cases are only positive.

Advertising positions the drug as one of the most effective in combating any kind of pain. What is its feature? How to take these pills correctly? About all this can tell the instructions for use.

Description of the medicinal product, composition

Tablets painkillers "Next" are a drug containing just two active ingredients: ibuprofen and paracetamol in an amount of 400 and 200 mg respectively. Tablets are oval in shape and covered with an enteric film membrane of a red color. On one side of it is cross-sectional risk. At the break of the tablet you can see a white or almost white core. Tablets do not have a pronounced taste, but they must be taken without chewing.

In addition to the active components, in the formulation of the drug "Next" the instruction for use mentions auxiliary substances. These are microcrystalline cellulose, sodium croscamellose, magnesium stearate, aerosil and calcium hydrogen phosphate. These elements form the core of the tablet core "Next". The composition of the shell includes dyes, polyethylene glycol, polysorbate, polyvinyl alcohol, titanium dioxide, giprolose and talc.

The medicine "Next" is packaged in branded cardboard boxes with the logo of the manufacturer. Each box can contain 1 or 2 contoured honeycomb packs with 2, 6, 10 or 12 tablets.

Pharmacological properties of the preparation

The "instruction" (tablets) refers to non-steroidal anti-inflammatory drugs. This is due to the fact that one of the active components (ibuprofen) refers specifically to this group of drugs. Paracetamol, in turn, is an analgesic-antipyretic. In a word, "Next" instructions for use refer to a combination of drugs that can not only relieve the pain of almost any origin, but also contribute to lower body temperature. Also, the drug has a pronounced anti-inflammatory effect.

Let us consider in more detail the pharmacological properties of each component of the preparation. Paracetamol affects the synthesis of cyclooxygenase and receptor susceptibility to the effects of this compound. This active substance acts more on the receptors of pain in the central nervous system. Ibuprofen has a suppressive effect on cyclooxygenase non-selective method, due to which it has the property of regulating the synthesis of prostaglandins, that is, it effectively affects the receptors of pain in the peripheral parts of the body.

After taking the tablets "Next" their effect becomes noticeable after 25-45 minutes. The half-life of active components is 1-4 hours from the time of taking the medication.

Indications for use

"Next" (tablets) instruction for use recommends taking as an anesthetic in the following cases:

1. With a headache of various etiologies, including migraine, pain caused by excessive contraction of the muscles of the head and shoulder girdle.
2. At feverish conditions, caused by inflammatory diseases of an infectious and viral origin occurring in the body.
3. With spasms of smooth muscles of internal organs, including algodismenorea, intestinal pains, etc.
4. With back pain caused by inflammation of the muscle fibers (myalgia).
5. With joint pain caused by degenerative changes in the locomotor apparatus.
6. With neuralgia.
7. With toothache.
8. With fractures, bruises and other injuries, as well as during recovery in the postoperative and post-traumatic period.

In situations where pain resumes for several days, it may be necessary to visit a doctor. Sometimes a seemingly banal or weakly expressed pain can hide a serious illness. Prolonged taking of painkiller "Next" not only smears the picture, but also inevitably leads to disruptions in the work of many internal organs.

Contraindications

The instructions for use contain information about contraindications to the use of the drug "Next". Tablets should not be taken to those who have intolerance or hypersensitivity to the constituent components. In addition, there is a fairly extensive list of conditions under which the use of this drug requires caution. One of the contraindications to taking the drug "Next" - a child's age (up to 12 years). In addition, special attention should be given to the weight of the patient when prescribing the drug: persons whose body weight has not reached 40 kg may need to abandon its use.

The drug "Next" is not safe for newborns, therefore, nursing mothers should stop breastfeeding for the time of taking it until the components of the medicine are completely removed from the body. The third trimester of pregnancy is also a contraindication to taking these tablets.

There are a number of ailments in which it is not recommended to take the drug "Next" (tablets). Instruction in this case mentions the following diseases:

• Erosive and ulcerative lesions of the gastrointestinal mucosa in the stage of exacerbation, including with bleeding, gastritis, enteritis and colitis;
• Cardiac, renal and hepatic insufficiency in severe form;
• Hyperkalemia;
• Diseases of the hematopoiesis and blood circulation system, including hemophilia and hemorrhagic diathesis;
• Bronchial asthma and recurrent polyposis of the nasal cavity and sinuses, combined with intolerance to NSAIDs;
• Recovery period after coronary artery bypass grafting;
• Liver disease, including alcoholic or viral hepatitis, liver cirrhosis;
• Nephrotic syndrome;
• diabetes.

Before using the medication, you need to make sure there are no contraindications. To do this, it is enough to consult a doctor who can study your history for the presence of allergic reactions to medications, as well as identify diseases in which taking this medication can be dangerous.

Information on overdose and side effects

Regarding the side effects that may appear during the reception of the drug "Next", the instruction manual contains detailed information that you can read in the table below.

With prolonged use of the drug "Next" tablets can provoke the appearance of all the above-mentioned adverse reactions in a more complex form. In addition, their nephrotoxic and hematotoxic effects on the body are intensified. In this regard, it is not recommended to use this drug for longer than 3-5 consecutive days.

Recommendations for dosing of tablets "Next": instruction

According to the instructions for use, to drink tablets "Next" is better after eating. In this case, they do not have a pronounced effect on the mucous membranes of the digestive tract. Daily dosage for adult patients should not exceed 3 tablets (one for each dose). For children over the age of 12 years, the daily dose is slightly lower and is 2 tablets.

The duration of therapy with the drug "Next" depends on whether it is taken as an anesthetic or as an antipyretic. In the first case, the duration of admission is a maximum of 3 days, in the second - no more than 5 days. If the patient is required to continue taking the drug "Next", the instruction for use advises to consult a specialist for advice.

special instructions

When taking the medication, you should ensure that the patient does not use other drugs that contain NSAIDs and paracetamol, as this can lead to an overdose. When extending the course of treatment with the "Next" tablets, it is necessary to monitor and, if possible, monitor the laboratory parameters of peripheral blood and the state of the liver and kidneys.

Within a day after taking the drug, laboratory indicators for blood glucose and uric acid may be distorted. Before taking blood for analysis, tell the doctor or laboratory worker that you have taken this medicine. Also, tablets "Next" can distort the picture when examining blood (or its plasma) for 17-corticosteroids. Before passing this survey, it is necessary to cancel the drug two days before collection of materials.

Patients taking the drug "Next" are not recommended to use alcohol-containing beverages. In addition, there is a possibility of injury due to the occurrence of adverse reactions from the nervous system. Therefore, during treatment, this means should abandon those activities that require increased concentration of attention and quick response.

Drug Interactions

Since the analgesic tablets "Next" contain just two active components, the list of its drug interactions includes several more items than other, one-component drugs. Some drugs reduce the toxic effect of components, others enhance. It is important for every patient to know about unfavorable combinations of drugs with the "Next" tablets, in order to avoid serious consequences for the body.

So, let's pass to the main question: with what preparations should tablets "Next" be better not taken? First of all, it is worth mentioning a variety of tinctures containing ethyl alcohol. The fact is that ibuprofen in combination with alcohol is much more likely to cause erosion and ulcers on the mucosa of the gastrointestinal tract. The same effect on the body has a combination of tablets "Next" with glucocorticosteroid. Paracetamol also reacts with alcohol-containing beverages and medicines. In this case, the patient can develop pancreatitis in an acute form.

Drugs containing barbiturates and tricyclic antidepressants can not only reduce absorption of paracetamol, but also cause severe poisoning. It is especially dangerous to take such substances together with increased doses of "Next" tablets.

Both active substances (paracetamol and ibuprofen) influence the uptake and effectiveness of anticoagulants. Before using an anesthetic and medications that reduce blood clotting, you should consult your doctor about adjusting the doses of the drugs. This same action will be required with the simultaneous administration of an anesthetic and insulin-containing drugs and vasodilators.

Storage and dispensing from pharmacies

Tablets "Next", the price of which is not too high, are dispensed over-the-counter. However, this does not mean that you can accept them without exception. As mentioned above, the advisability of using tablets is determined by the absence or presence of contraindications in the patient.

Storage of the drug should be carried out according to the rules generally accepted for all medicinal products. Tablets should not be exposed to direct sunlight, too high or low temperatures. The ideal storage medium is a dark, dry, ventilated room with a temperature of 17-25 degrees. It is necessary to provide for the fact that the drug is dangerous for children. In this regard, it is not recommended to leave the tablets in the area of their access.

The shelf life of the drug is limited to a period of two years. After this period, they should not be used.

How much are the tablets "Next": the price

The drug can be found in almost any pharmacy. Its cost depends on how many tablets are contained in the package. For example, 6 tablets cost from 90 to 126 rubles. Larger packages cost from 145 to 180 rubles. In this case, any one contains the drug in a single dosage.

Conclusion

We told everything about the drug "Next" (pills). Instruction, price, pharmacological properties, indications for use, etc. have been described in detail in this review. Finally I would like to note the following: try nevertheless, as necessary, to see a doctor. Do not self-medicate!