Instructions for use "Neurorubin", price, composition

This article presents a complete description of the drug Neurorubin. The price of the drug will also be indicated in the review. Here you will learn about the composition of the drug, its properties, indications for use, adverse reactions, peculiarities of use, and so on.

Attention! Information on this pharmacological agent is provided for information only and is not recommended for use in the self-medication process. The article presents not an official instruction on the use of Neurorubin, but its simplified version. Before you buy and start using the medicine, you need to consult a doctor. Only a specialist can decide on the appointment of this drug, determining the optimal dosages and methods of application for you.

Form of production of the drug "Neurorubin"

The drug "Neurorubin" is produced in the form of:

1. Tablets - round, convex on both sides, having a pink color, the inscription "TP" and the film membrane. Packed in 10 pieces in blisters, which, in turn, are packed 2 in cardboard boxes.

2. Solution for injection (transparent, red in brown glass ampoules). Each contains 3 ml of the drug and is packaged in an amount of 5 pieces per carton of cardboard.

Composition of the drug Neurorubin

The drug "Neurorubin" (ampoules) contains: in 3 ml - vitamins B1 (thiamine hydrochloride) and B6 (pyrodoxin) for 100 milligrams, B12 (cyanocobalamin) - 1 mg. The solution contains auxiliary substances - benzyl alcohol, potassium cyanide (0.25 mg), and water for injection.

The drug "Neurorubin Forte Lactab" (tablets) contains in its composition thiamine mononitrate - 200 mg, cyanocobalamin - 1 mg, pyridoxine hydrochloride - 50 mg. Also, in the drug of this form of release, there are auxiliary components. The number of ingredients is based on 1 tablet. The auxiliary compounds include: colloidal silicon dioxide, microcrystalline cellulose, pregelatinized starch, magnesium stearate, hypromellose, powdered cellulose, mannitol. The film shells of the tablets "Neurorubin" contain talc, erythrosine, macrogol-6000 and titanium dioxide.

Pharmacological action of the drug "Neurorubin"

What is the drug "Neurorubin" for? The medication instruction explains that it is a drug consisting of a complex of neurotropic B vitamins that are important for the metabolism of proteins, fats and carbohydrates.

Pharmacokinetics and pharmacodynamics of the drug "Neurorubin"

Next, we will talk about what processes in the human body are affected by the components of the drug. The official instruction for the application of Neurorubin provides a clear description of the actions of each of them. Despite the fact that the complex compounds of the drug belong to the same group of vitamins, each of them is distinguished by its inherent spectrum of biological activity. Acting in a complex way, they stabilize the work of the nervous system and have a beneficial effect on carbohydrate, fat and lipid metabolism.

Vitamins B1, B6 and B12 dissolve in water and are absorbed by the human body completely immediately after insertion into muscle tissue.

Vitamin B1

Vitamin B1 actively participates in the process of metabolism of proteins, fats and carbohydrates. With a lack of thiamine in the human body, the level of lactic and pyruvic acid increases. In this case, vitamin B1 comes to the rescue. Thanks to it, the process of re-and deamination of lactate and pyruvate is started.

Thus, vitamin B1 normalizes the exchange of proteins. It also acts as a catalyst during the process of metabolism of fats and their acids, activates ion channels, interacts with cell membranes, stimulates peristalsis and secretory function in the intestines.

Vitamin B1 is excreted partly from the body in an unchanged state, the rest is evacuated in the form of pyramine and thiamine carboxylic acid.

Vitamin B6

Vitamin B6 actively affects the metabolism of fats and proteins. He also participates in the synthesis of enzymes and hemoglobin. Pyridoxine favors the formation of myelinic neuronal membrane and is an integral part of lipid metabolism. In addition, vitamin B6 is involved in the process of connecting the neurotransmitters and hemoglobin in the synapses of the nervous system. Also, pyridoxine hydrochloride acts as a coenzyme in the enzyme reactions.

Vitamin B6 accumulates mainly in muscle tissues in the form of phosphoric ether. It is excreted from the human body mainly in the state of pyridoxic acid.

Vitamin B12

Vitamin B12 is an indispensable participant in protein metabolism, regulates the production of nucleic and amino acids, purines. Cyanocobalamin is vital for the human body, as it affects the process of myelination of neurons and the production of acetylcholine. In addition, vitamin B12 influences positively on the restoration of the fibers of the nervous system and stimulates the production of impulses in its peripheral structures.

Cyanocobalamin is a hematopoietin. This means that it promotes the formation of substances in the human body that stimulate the process of maturation of blood cells and normalizes the rate of its coagulation.

Vitamin B12 is accumulated mainly in the liver and is excreted from it for about one year.

Medicinal product "Neurorubin": indications for use

The drug "Neurorubin" (tablets) is used to prevent such human health conditions when there is a lack of B vitamins. Also, the medicine is used to treat the following ailments: diabetic polyneuropathy, neuralgia, intoxication (alcoholic including), polyneuritis.

The drug "Neurorubin" (injections) is used as a separate therapeutic agent and in combination with other medications. By injection, the drug is administered in the following diseases: neuritis (chronic and acute including), beriberi (with wet and dry form), diabetic polyneuropathy.

Contraindications to use

Instructions for use "Neurorubin" informs about the contraindication to the use of both forms of the drug in such ailments and conditions: in pregnancy and lactation, under the age of 18, with diathesis of an allergic nature, in case of hypersensitivity to the components of the drug. The use of both tablets and injectable solution "Neurorubin" can lead to complication of psoriasis and aggravation of acne.

Side effects

Are there side effects when using Neurorubin? The instruction warns about the following deviations:

• headache;
• Nausea;
• Vomit;
• Increased irritability;
• Gastric bleeding;
• Increase in the number of hepatic transmissions;
• Unreasonable anxiety;
• Tachycardia;
• Feelings of anxiety;
• Sensory neuropathy;
• Pulmonary edema;
• Itching, rashes on the skin;
• Circulatory collapse;
• Urticaria;
• Increased sweating;
• Edema of Quincke;
• Cyanosis;
• Development of acne;
• Anaphylactic shock.

The drug "Neurorubin": application (dosage and way of consumption)

The dosage of the drug "Neurorubin" and the duration of therapy is determined by the attending physician, who, when prescribing the drug, is based on the patient's condition and the nature of the disease.

According to the instructions, the tablet form of the medication is consumed before, after or during meals. The drug should be swallowed, not liquid, squeezed boiled water at room temperature. Therapeutic dose of tablets "Neurorubin" - 1-2 pieces per day.

In the form of injections, the drug "Neurorubin" is introduced to relieve the pain syndrome. Depending on what severity of the disease, injections are done daily or once for two days. The injection solution is injected into the muscle tissue of the buttocks. With the improvement of the patient's condition, the drug "Neurorubin" is used to maintain the therapeutic effect twice during each week.

The duration of the course of taking this medication is one month.

Overdose

In case of exceeding the dosage of the drug "Neurorubin", usually there is an aggravation of side effects. In this case, the patient is prescribed gastric lavage and therapy, depending on the symptoms.

True, there are isolated cases when, with excessive use of this drug, reversible sensory peripheral neuropathy arose. After discontinuation of the drug, the patient's condition returned to normal.

Interaction of the drug "Neurorubin" with other drugs

On the parallel use with other medications instruction on the use of "Neurorubin" says about the unwanted joint therapy with substances altretamin and levodopa. The reason is a decrease in their effectiveness by group B vitamins.

Do not use the drug "Neurorubin" at the same time as any form of the therapeutic agent "Isoniazid". Otherwise, the toxic effect of the latter increases.

Medications "Fluorouracil" and "Thiosemicarbazone" have opposite acting abilities with respect to vitamin B1. Therefore, their parallel application is not recommended.

Also, simultaneous use of the drug "Neurorubin" with drugs that have antacid and enveloping properties is not acceptable, since they reduce the absorption of the drug described by us.

Terms of sale and storage of the drug "Neurorubin"

The drug "Neurorubin" is released, the price of which will be indicated below, in pharmacies without prescription.

Keep the tablets at room temperature, which is not below +15, but does not exceed +25 degrees Celsius. The drug should be inaccessible to children. The place where it is located should be dry and protected from direct sunlight. Ampoules with a solution for injection "Neurorubin" should be stored at a temperature of +2 to +8 ºC.

Shelf life of Neurorubin is 48 months from the date of manufacture.

Features of the drug "Neurorubin"

Care should be taken to use the drug "Neurorubin" for people with angina or heart failure.

It is extremely rare, but there are cases of developing sensory neuropathy with prolonged use of the drug in large quantities. After stopping the reception of "Neurorubin" tablets, the patient's condition improves noticeably.

In connection with such side effects arising from the use of the drug, such as dizziness, anxiety, weakness, anxiety, caution should be exercised in the case of driving and performing work that requires high concentration.

Use of Neurorubin during pregnancy and lactation

As mentioned above, during pregnancy and while breastfeeding the baby, it is forbidden to use both tablets and injectable solution "Neurorubin". In fact, there is no data on the safety of the drug in such cases.

But, despite the ban, there are exceptions. The doctor can prescribe the drug "Neurorubin" to a woman during pregnancy or lactation. Sometimes this is permissible in case of emergency, provided that the alleged help to the body exceeds the likely harm from the drug. Then with lactation it is necessary to interrupt the feeding of the child. Otherwise, the complex of B vitamins will overcome the hematoplacental barrier and under their influence the composition of milk will change. This, of course, will affect the child's health negatively.

The drug "Neurorubin": the price (tablets and ampoules)

The cost of the vitamin complex "Neurorubin" depends on the region of the country in which it is sold, and on the form of the drug. On average, the price of tablets in various regions of Russia starts from 605 rubles.

That's all the reference and general information about the drug "Neurorubin". The instruction, the price of the drug testify to the high effectiveness of the medication and its availability for each patient. The main thing - do not self-medicate, and health will be in order.