Injections "Kokarnit": the instruction. "Kokarnit": reviews, analogues

Metabolism, or metabolism is called a set of chemical reactions that occur in the body to maintain its life. These processes promote growth and reproduction.

Metabolism is usually divided into two stages:

• In the process of catabolism, complex organic substances are transformed into simple ones;
• In the course of anabolism, together with energy costs, proteins, nucleic acids, lipids and sugars are synthesized.

With disturbed metabolism, human health deteriorates noticeably. There are various diseases, fatigue, general health worsens, weight and so on.

To normalize metabolism, experts recommend a healthy lifestyle, eat right, exercise, etc. In addition, patients can be assigned metabolic drugs. One of the most popular of these is the "Cockarnit" medication. Instructions for use, feedback on this tool will be provided later.

Form of release, package of medicine and its composition

In what form is the Cocariton drug sold? The instruction informs, that the given medicine is made in the form of lyophilizate for solution preparation, and also solvent (lidocaine) in ampoules.

The composition of this drug includes nicotinamide, cocarboxylase, cyanocobalamin and adenosine triphosphate. As additional components, glycine, propyl parahydroxybenzoate and methyl parahydroxybenzoate are used.

Pharmacodynamic features

What is the means we are considering? What does the instruction say about it? "Cockartite" is a complex of vitamins and substances that affect metabolism. It has a neurometabolic and analgesic effect, and also affects the emotional-vegetative sphere.

The effectiveness of this drug is due to its composition. Let us consider the characteristics of each substance in more detail.

Nicotinamide positively affects carbohydrate and nitrogen metabolism, takes part in oxidation-reduction processes, and also facilitates the transport of ATP to cells. Also this substance has sedative properties. In this regard, it is very effective in neuropsychiatric disorders, depression, anxiety and diminished attention.

Cocarboxylase is a coenzyme that plays a huge role in carbohydrate metabolism, affects the synthesis of nucleic acids, improves the trophism of tissues, lipids and proteins, and promotes the absorption of glucose.

Adenosine derivative is called adenosine triphosphate. This component stimulates metabolic processes. It is the main energy substrate of cells. With ischemic disease, an energy deficit develops, which can be reduced by adenosine triphosphate. Its transportation to the cells is due to nicotinamide. Adenosine triphosphate is able to have antiarrhythmic, hypotensive and vasodilating action.

As for cyanocobalamin, it synthesizes and stores proteins, activates the metabolism of carbohydrates and fats. The result of this action is a decrease in the level of cholesterol, as well as a warning of fatty hepatosis.

It should also be noted that cyanocobalamin increases the regenerative capacity of cells, which is necessary for the functioning of the hematopoietic organs, the liver and the nervous system.

Indications

What diseases are prescribed such a drug as "Cockarnitus"? Instructions for use (injections should only be performed by an experienced medical professional) indicates that the indications of this remedy are:

• Neuritis;
• Neuralgia of different origin;
• Sciatica, lumbago, sciatica;
• Myalgia, tendonitis, bursitis;
• Neuropathy (including diabetes mellitus);
• Myocardiopathy, ischemic heart disease, myocarditis.

It should also be said that during pregnancy, this medication is used only if the benefits for the future parturient far exceed the risk to the fetus.

Contraindications

When should you not prescribe a "Cockarnit" medication? The instruction says that this medicine is contraindicated when:

• Hypersensitivity;
• Severe form of hypertension, as well as hypotension;
• Erythrocytosis, erythremia;
• Psoriasis;
• Conduction disorders and severe heart failure;
• Myocardial infarction in an acute period.

One can not help saying that the drug is carefully recommended to people with gastritis, peptic ulcer, gout and liver damage. Data on the use of this drug in small children are absent.

In addition, the following contraindications for a solvent in the form of 0.5% lidocaine should be taken into account when administering the medicament: Adams-Stokes syndrome, sinus node weakness syndrome, stress angina, Wolff-Parkinson-White syndrome, myasthenia gravis, epileptiform cramps associated with lidocaine , Severe renal failure and porphyria.

"Cocarnite" injections: instruction

Feedback about this tool will be described below.

According to the instructions, this drug should be administered intramuscularly for 1 or 2 ampoules every day. The injections are done in courses. Their duration depends on the severity of the disease.

The medicinal solution is used immediately after preparation. In this case, it must be red. If the color does not change, then use the drug is prohibited.

Using the "Cockarnit" medication, the instruction of which is enclosed in a pack of cardboard, regular monitoring of red blood cells and platelets, clotting time, uric acid, bilirubin and transaminases should be carried out regularly.

Side effects

What are the negative consequences after using the drug Cocariton? Instruction for use indicates that this drug can cause:

• Tachycardia;
• headache;
• Urticaria;
• weakness;
• Sweating;
• dizziness;
• Skin rashes;
• anaphylactic shock;
• Itching;
• Diarrhea;
• Peripheral vascular thrombosis;
• pulmonary edema.

It should also be noted that hypersensitivity patients undergo an intradermal test prior to administration of the drug.

An overdose of a drug

What will happen with an overdose of "Cockarnit"? Instructions for use (injections should be prescribed only by a specialist) states that if you ingest the drug inwardly, you may experience toxicity, which is expressed by skin flushing, itching, nausea, headache, vomiting, or heartburn.

Chronic intoxication of the drug is characterized by an increase in the level of uric acid and glucose, as well as the appearance of ulcers in the 12-типерстной gut.

Interaction with other medicines

Is it possible to use the drug "Cockarnit" (injections) with other drugs? The instruction says that the cocarboxylase, which is part of the medicament, is able to enhance the cardiotonic action of cardiac glycosides.

As for nicotinamide, it potentiates the anticonvulsant properties of antiepileptic drugs (for example, Diazepam, Carbamazepine, Valproate).

Adenosine triphosphate together with potassium-sparing diuretics, potassium preparations and ACE inhibitors increases the risk of hyperkalemia. It also increases the effect (antianginal) of nitrates and beta-blockers.

When taking medication together with "Dipiridamol", its vasodilating action is enhanced.

Xantinol nicotinate reduces the effectiveness of adenosine triphosphate, and "carbamazepine", on the contrary, enhances its effect.

Together with "Theophylline" and caffeine antagonism is manifested.

Drug absorption is reduced by potassium preparations, cyanocobalamin aminoglycosides, antiepileptic drugs, salicylates and "Colchicine".

The absorption of cyanocobalamin decreases with simultaneous administration with "Polymyxin", "Kanamycin", "Neomacin" and "Tetracyclin."

Cyanocobalamin is incompatible with ascorbic acid, Riboflavin, Pyridoxine, and salts of heavy metals.

Contraceptives for oral administration reduce the concentration of cyanocobalamin in the blood.

Cost and analogy

How much does the Cockarnit preparation cost? Instructions for use will not give an answer to the question. You can find it only in the pharmacy. As a rule, the price of this remedy for three ampoules varies within the limits of 120-150 rubles.

What can replace the metabolic solution "Cockarnitus"? Instructions, reviews say that there are no structural analogues to this drug. To replace it with similar means, you need to contact a doctor (most often recommend "Ismizhen", "Venohepanol", "Threw", "Orzipol", "Sterilium", "Diophlan", "Collomac", "Chondrosamine", "Endofalk", " Secnidox ").

Reviews

Now you know the principle of the drug "Cockarnitus". The instruction, analogue of this medication was presented above.

Most often this tool is used in neurological, cardiac and neurosurgical practice. Specialists note that this medication is able to reduce the amount of wound detachment, as well as eliminate vertebrogenic pain.

It should also be noted that the drug in question is well established in the complex therapy of patients with discogenic lumbosacral radiculitis. In this case, the drug should be used intramuscularly 2 ml per day for 2-3 weeks.

Side effects of this drug patients did not mention.