Hypofunction of the ovaries, symptoms and treatment

Ovarian hypofunction means a clinical term that includes diseases that differ in pathogenesis and etiology. All of them have similar signs of sexual underdevelopment. These include infertility, hypoplasia, amenorrhea, hypoestrogenia and hypotrophy of the uterus and ovaries.

There are many varieties of primary hypofunction. The primary, primary, clinical form of this disorder is premature menopause. Usually it develops in women over 35 years of age. In the etiology of the disease, the main role is played by various negative environmental factors. The cause of the disorder can be gene mutations, hereditary predisposition, autoimmune disorders in the ovaries.

Hypofunction of the ovaries can occur against the background of normal generative and menstrual functions. It manifests itself in the form of tides to the head, amenorrhea, excessive sweating, rapid fatigue, weakness, pain in the heart and head, reducing efficiency. During the onset of the disorder, it is determined: a reduced size of the uterus and ovaries, a low concentration of prolactin and estrogens, the absence of follicles and yellow bodies, increased follicle-stimulating and luteinizing hormones in the blood. This hypofunction of the ovaries has such treatment: the use of hormonal drugs (estrogen-progestogen and estrogen). Hormonal therapy significantly improves the condition of such patients, so when establishing this diagnosis, it is necessary to begin treatment immediately.

Isolated (secondary) ovarian hypofunction, organic and functional disorders of the hypothalamic-pituitary system functioning are important clinical forms of such disorder. Despite the fact that the ovaries have a normal number of follicles, they do not undergo the process of ripening. For this condition are inherent: hypotrophy, primary or secondary amenorrhea, hypoplasia of the uterus and ovaries, hypoestrogenia. This hypofunction of the ovaries usually occurs against the background of a normal content of follicle-stimulating and luteinizing hormones in the blood.

There is still a syndrome of polycystic ovaries. About 3% of young women suffer from this disease. This disorder is characterized by excessive production of androgens (in the adrenal and ovaries), glitches in their peripheral metabolism. Along with these signs, an increased amount of luteinizing hormones, a normal or decreased concentration of follicle-stimulating hormone, an increased content of prolactin in the blood is determined. Such hypofunction of the ovaries, symptoms: characterized by the development of pseudohermaphroditism, which are characterized by hyperandrogenism, clitoral hypertrophy, amenorrhea, infertility, anovulation and severe acne.

Another reason that can lead to ovarian hypofunction, may be a virilizing tumor of the ovaries. Tumor cells in the ovaries form an excessive amount of testosterone, dehydroepiandrosterone and androstenedione, which are male sex hormones. Clinical manifestations of the disease are lack of menstruation, irregular meager menstruation (oligoopsomenorea), acyclic uterine bleeding. This disease is characterized by the manifestations of alopecia, hirsutism, coarsening of the voice, the formation of the male type, the formation of pseudohermaphroditism, hypertrophy of the clitoris.

If there is ovarian hypofunction, treatment is prescribed after a comprehensive examination. When tumors are formed, chemotherapy, radiation and surgical removal of the tumor are performed. Hormonal disorders after a thorough examination are treated with various hormonal drugs.