Erythema nodosum

Nodulum erythema is a polyethological disease. In children, it manifests itself as a reaction to a tuberculosis infection, which coincides with the periods of exacerbation of tuberculosis of bones, lymph nodes, internal organs. In adults, erythema nodosum is formed as a toxic-allergic
Cardiovascular reactions to intoxication and chronic infections. Most clearly
A relationship with streptococcal infection in patients diagnosed with knot
Erythema, the causes of the disease can be covered in disorders of the intestinal microflora.
Sometimes the disease occurs as a result of intolerance to certain drugs,
Such as antibiotics, sulfonamides, vaccines, serums, bromides.

Symptoms are rashes, general malaise, subfebrile condition, pain in the joints and bones, gastrointestinal disorders. In adolescents and children, the acute course of the disease with rheumatoid pain predominates. On the extensor surfaces of the shins, thighs and forearms
There are painful symmetrical inflamed nodes in size from a pea. The nodes do not have clear boundaries and slightly rise above the surface of the skin. Chronic erythema nodosum is divided into several clinical varieties. The migratory form is characterized by a prolonged course and a tendency to relapse.
Surface-infiltrated erythema nodosum is characterized by a tendency to peripheral growth and large dimensions. Diseases are accompanied by
Fever, increased ESR, swelling and pain in the joints.

In the arterioles and capillaries, the lumen is narrowed until obliteration. Deep and flat knots often ulcerate and end with scarring atrophy. The disease, unlike toxicermy, is characterized by the dynamics of development of color, monomorphic nodes, localization on the anterior surfaces of the tibia in patients diagnosed with erythema nodosum, symptomatic treatment. With acute form of the flow in children, tuberculosis infection is detected and appropriate therapy is conducted. In older children, it is aimed at rheumatism and focal infection. In parallel antibiotics of a wide spectrum are appointed.

Widely used were chloride and calcium gluconate, rheopyrine, naprosin, pyrabutol, brufen, aminocaproic acid. In some cases, in the absence of tuberculosis, glucocorticoid hormones (urazone, prednisolone, dexamethasone) and antimalarial drugs (delagil, resichin) are prescribed. In the absence of contraindications, mercury-quartz lamps are irradiated, and vitamins such as aevit, ascorbic acid, and rutin are taken. UHF therapy, solux, dythermia is used. External compresses are applied from a solution of ichthyol, azamine ointment, absorbing ointments of Mikulich, Krede or Vishnevsky.

In acute nodosum erythema, patients are recommended bed rest. Forecasts for life are favorable. Sometimes there are cases of familial erythema nodular, caused by the taking of certain biological drugs and oral contraceptives. There is also a mixed form of the disease, in which it is impossible to determine the apparent causes of the disease. Nodular erythema, the causes of which are diverse, is a fairly rare syndrome, observed mainly in women. The disease can be detected at any age, but most often occurs in children under 2 years old and young people. The prevalence of the syndrome depends on the severity of the negative factors, which include the time of year, geographical location. In connection with the effectiveness of treatment of mycobacterial and streptococcal infections in recent years, the incidence of erythema nodosum has significantly decreased.