"Design" (tablets from allergies): instructions for use, analogues, reviews

How to apply the drug "Design"? Instructions for using this tool will be provided later. Also you will learn about what components are included in the composition of the medicine, in what form it is produced, whether it can be administered to children and pregnant women.

Composition, form, description of the medicinal product

What components does the preparation "Dizal" include? Tablets from allergies, the instruction of which is enclosed in a cardboard package, have a blue color, biconvex and round form, and also engraving "LT" on one side. The active substance of this drug is desloratadine. It also contains additional ingredients in the form of microcrystalline cellulose mannitol, corn pregelatinized starch, magnesium stearate and talc.

As for the film coating of tablets, they include blue opadrai, macrogol and indigo carmine dye.

It should also be noted that the drug in question is available in the form of a syrup. Desloratadine also acts as its active substance.

Pharmacology

How does the medication "Dizal" (tablets from allergies) work? The instruction, attached to this remedy, reports that this is an antihistamine drug of long duration. It is a blocker of peripheral histamine H1 receptors.

The active substance of this medication is the primary active metabolite of loratadine. It inhibits allergic reactions, releasing pro-inflammatory cytokines and chemokines. Also, this component reduces the production of superoxide anions, chemotaxis and adhesion of eosinophils.

This exposure to the drug helps prevent development and alleviate allergic reactions. This drug has antiexudative and antipruritic properties, it prevents the development of spasms of smooth muscles, edema of tissues and reduces the permeability of capillaries.

Tablets "Dizal", the price of which will be listed below, has no effect on the central nervous system, and also has no sedative effect (that is, it does not cause drowsiness) and does not affect the psychomotor reaction of a person (when taking the recommended dosages). In addition, the drug does not extend the QT interval on the ECG.

The therapeutic effect of this drug begins within half an hour after ingestion and lasts throughout the day.

Pharmacokinetics

What pharmacokinetic parameters does the "Dizal" medication (allergy pills) have? The instruction says that after taking the drug its active substance is well absorbed from the digestive tract. In blood plasma, it is determined after half an hour, and its maximum concentration is reached after about three hours.

Communication with plasma proteins of the drug is 85-87%, and the half-life is about 28 hours. Desloratadine is excreted through the intestine (less than 7%) and urine (less than 2%).

Indications for use

From the allergy on the face this drug helps very well. It is used not only to alleviate, but also to eliminate the following symptoms:

• Urticaria (rash and itchy skin);
• Allergic rhinitis (rhinorrhea, sneezing, itching of the sky, nasal congestion, redness and itching of the eyes, itching in the nose, lacrimation).

Contraindications for use

From the allergy during pregnancy, the preparation "Dizal" is prohibited. Also, it is not prescribed for breastfeeding and in children under 12 years of age (safety and efficacy have not been established). Do not use this medication and with increased sensitivity of the patient to the active or any additional ingredient of the drug.

With extreme caution, the "Diazal" tablets are prescribed for severe kidney failure.

The drug "Dizal" (tablets from allergies): instruction

Appoint such pills should only a narrow specialist. Allergy (urticaria, pruritus, rash, etc.) in children aged 12 and older is treated the same. According to the instructions, the tablets must be taken orally, regardless of the meal. The dosage of this medication is determined by the doctor and, as a rule, it is 5 mg once a day (i.e., 1 tablet per day).

Adverse Reactions

From the allergy for children over 12 years of age, the drug "DysAul" should be administered with extreme caution. This is due to the fact that this medication can cause a large number of side effects.

More often than others, such undesirable reactions as increased fatigue, persistent headaches and dryness of the oral mucosa are noted in patients.

During the observation, other side effects were also identified. Imagine them right now:

• From the nervous system may be noted drowsiness, psychomotor hyperactivity, dizziness and insomnia.
• From the side of the digestive tract, abdominal pain, diarrhea, nausea, dyspepsia and vomiting are observed.
• On the part of the bile duct and liver, there are such phenomena as an increase in the concentration of bilirubin, an increase in the activity of hepatic enzymes and hepatitis.
• Tachycardia and palpitations are disturbing from the heart and vessels of patients.
• From the bony and muscular system, myalgia is observed.

It should also be noted that against the background of taking the drug in question, patients may have mental disorders in the form of hallucinations and allergic reactions in the form of itching, anaphylaxis, rash, angioedema and urticaria.

Signs of an overdose

From allergies for children over 12 years old, as well as for adults, the drug "Dyshal" should be taken in the recommended dosage.

When taking the drug in high doses (for example, 9 times, which is 45 mg), there are no clinically significant signs. However, drowsiness may develop.

As a treatment, it is required to rinse the stomach and take activated charcoal. It should also be noted that desloratadine is not excreted by hemodialysis.

Compatibility with other medicines

The interaction of the drug "Dasal" with other medications was not detected (including with "Erythromycin" and "Ketoconazole"). Also it should be said that desloratadine does not enhance the effect of ethanol on the central nervous system.

Special Recommendations

Allergies (urticaria, pruritus, rash, etc.) in people with severe renal dysfunction should be treated with particular caution.

According to studies, the drug "Dasal" does not affect the management of the patient by vehicles. But you should always consider that very rarely some people develop drowsiness. In this case, special care must be taken when driving and working with complex machinery.

Cost and analogues of medicinal product

In contrast to other antiallergic drugs, the price of the drug "Dizal" is not very high. You can buy this medication for 200-350 rubles (10 and 30 tablets respectively).

As for the analogs of the medicine in question, there are a lot of them. Let us list them: "Lordestin", "Blogger-3", "Erius", "Desloratadine", "Elisei", Desloratadine-Teva, Ezlor, Desloratadine Canon, Nalorius, Desloratadine-Pharmaplant.

Reviews about the antiallergic drug

The drug "Design" - an inexpensive drug against allergies, which is left with a lot of both negative and positive feedback. Most patients report that this medication copes well with the task. It quickly and effectively eliminates all the symptoms of an allergic reaction, significantly improving the patient's well-being.

People who took tablets "Dizal", testify that it is very convenient to use them. Unlike other drugs, this medication is enough to take once a day and you can forget about allergies.

There are negative reviews about this medicine. Many patients can not take it, because they immediately manifest allergic reactions. Such sick doctors prescribe safer drugs.