"Clotrimazole" (ointment): what helps, composition and reviews

What is a remedy like Clotrimazole (ointment)? What is it used for, and how should it be used? This is what we will discuss in this article.

Form, description, composition

Ointment "Clotrimazole" - what helps? Before answering this simple question, you should tell what the drug is. As is known, it is intended for dermal application. A homogeneous 1% ointment has a white or slightly creamy color, and also contains an active substance such as clotrimazole.

In addition to the main component, this drug also contains auxiliary ingredients in the form of polyethylene oxide 1500, propylene glycol, nipagine (methylparahydroxybenzoate), polyethylene oxide 400 and methylparaben.

In what packing is the Clotrimazole Ointment sold (what helps this remedy, you can find out from the attached instructions)? According to consumers, this product can be purchased in 30 g aluminum tubes, which are placed in packs of cardboard.

Pharmacological characteristics

What is remarkable about the drug "Clotrimazole" (ointment)? What helps with this drug? Experts argue that this remedy is an antifungal medication for topical use that has a wide range of effects.

Why is the antimycotic property of this drug due? This effect is associated with an active component of an ointment, an imidazole derivative.

After the application of local medication, there is a disruption of the synthesis of ergosterol, which is part of most cell membranes of fungi. This process changes their permeability, and then causes lysis of the cell.

How does the drug Klotrimazol (ointment) work? What helps this medication? In high concentrations, the drug acts fungicidal, and in small - fungistatically.

It should also be noted that this drug has an effect not only on proliferating cells. According to experts, in fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes. As a result, there is an increase in the concentration of hydrogen peroxide, which reaches a toxic level. This process contributes to the death of fungal cells.

With respect to which fungi is the most effective drug "Clotrimazole"? What helps with this medicine? According to the instructions, it works well against dermatophytes, pathogens of multi-colored lichen, mold and yeast-like fungi, as well as the causative agent of erythrasma. It should also be noted that this drug exhibits high antimicrobial activity against staphylococcus, streptococcus, gram-negative bacteria and Trichomonas vaginalis.

Kinetics

Now do you know what "Clotrimazole" (ointment) is? What this medicine helps with, we also told above.

What kinetic properties are characteristic of this drug? Experts argue that its active component is rather poorly absorbed through the skin and mucous membranes, and also has almost no systemic effect.

According to the instructions, the concentration of this remedy in the deep layers of the epidermis is much higher than that required to suppress dermatophytes. It should also be noted that when applied externally, the concentration of the drug substance in the epidermis is significantly higher than the concentration in the subcutaneous tissue and dermis.

The drug "Klotrimazol" (ointment): what helps?

Indications for use in this tool is a huge number. Experts argue that the drug in question manifests itself effectively when:

• Pancreatic lichen, erythrasis and superficial candidiasis caused by dermatophytes, as well as mold, yeast and other pathogens and fungi, sensitive to the active substance of the drug;
• Mycosis of the feet and skin folds, as well as fungal skin damages;
• Mycoses, which are complicated by secondary pyoderma.

Prohibitions to use

Does the ointment "Clotrimazole" have contraindications? What helps (the price of the drug is listed below) is this medicine, we described above. As for the prohibitions on its use, they are as follows:

• The first trimester of pregnancy;
• Hypersensitivity to the elements of the drug.

With special care, the drug in question is recommended for use during breastfeeding.

Ointment and cream "Clotrimazole": instruction

This medication is for skin use only. Ointment "Clotrimazole" should be applied a thin layer on dry and pre-cleaned affected areas two or three times a day. For greater effectiveness, the drug should be gently rubbed with soft and massaging movements. Before applying the medication, it is advisable to wash the affected skin with soap with a neutral pH.

The duration of therapy with this remedy depends on the severity of the disease, as well as the effectiveness of treatment and the localization of pathological changes.

Dermatomycosis is treated with "Klotrimazol" ointment for at least 4 weeks, and pityriasis is 7-22 days.

With fungal lesions of the skin of the legs, it is advisable to continue therapy for 2 weeks after the elimination of the main signs of the disease.

Side effects

In some cases, when using the local drug "Clotrimazole", the patients experience the following side effects: itching, tingling at the places of application of the cream, burning, the appearance of blisters, erythema, swelling, peeling and irritation of the skin. It is also possible to have an allergy in the form of hives.

Symptoms of overdose and drug interaction

According to experts, the use of the drug in question in large quantities does not cause any conditions and reactions that are dangerous for the patient's life.

As for the interaction of this remedy, when combined with Amphotericin B, natamycin and nystatin, its effectiveness is significantly reduced.

When using ointments with other agents, no significant negative interactions should be expected. This is due to the fact that the resorption capacity of the drug in question is very low.

Pregnancy and feeding of the baby

As mentioned above, in the first trimester of pregnancy the use of this medication is contraindicated. It should be noted that during the experimental and clinical studies it was not established that the use of the ointment in question during the period of gestation or during breastfeeding by the baby in any way has a negative impact on the health of a woman or a child. However, only an experienced specialist should decide whether to use this remedy.

The application of this medication directly to the breast is contraindicated.

Special Information

What do you need to know about the effects of a drug such as Clotrimazole? Ointment - helps with thrush or not? The instruction says that this remedy is effective against fungi of the genus Candida. Therefore, it is not forbidden to use it against thrush. However, before this, you should consult a doctor.

It is highly not recommended to apply the drug to the skin in the eye area. When treating onychomycosis, it is advisable to ensure that the processed nails are short-cut or have an uneven / rough surface, so that the active substance penetrates better into the affected areas.

People with liver failure need to periodically monitor the liver and its work.

If irritation or hypersensitivity symptoms appear, the ointment is stopped. If there is no therapeutic effect within 4 weeks, it is necessary to confirm the diagnosis.

Reviews about the drug

Most consumers who use the drug Klotrimazol, speak of it exclusively on the positive side. According to them, this drug helped them get rid of fungal skin and nail damage, and did not cause any side reactions. Also, many patients are pleased with the affordable price of this product. It is about 50-80 rubles.