Cholagogue means.

Currently, among diseases, a special place is occupied by pathologies of the liver and gallbladder. Speaking of violations in the functioning of the liver, you can give examples of numerous pathologies: hepatitis, cirrhosis, as well as dystrophies of various genesis. Most of these diseases lead to a violation of the synthesis of bile acids (bile). As for the gallbladder, the main disturbance in his work is the reduction of contractile activity.

There are special substances that promote the activation of the liver (especially its exocrine function), which in turn leads to increased excretion of bile in the lumen of the duodenum. Such cholagogue funds are now actively used in the practice of therapy of various pathological conditions. In the first place, these drugs are used for hepatitis, cholecystitis and cholangitis. Infectious processes involving structures of the liver, gall bladder or bile ducts also indicate the need for the use of drugs.

All cholagogue drugs are divided into those that increase the production of bile (choleresis), and those that activate the secretion of bile (cholekinosis). There are also medicines that affect both mechanisms. Cholestics in turn are divided into true (which increase the amount of bile due to the production of bile itself) and false (which increase the content of bile water).

Cholagogue funds are represented by preparations based on bile acids (for example, drugs Allochol and Cholenzym). In addition to these medicines, synthetic pharmaceutical agents ("Oxafenamide", "Nikodin") can be used. And also cholagogue tea can be used. Most often used decoctions or preparations based on tansy, volostushki and corn stigmas. It should be noted that drugs based on medicinal plants have a pronounced therapeutic effect. So cholagogue grass immortelle sand, used in the first few days of the disease, can remove all the symptoms of the pathological condition.

It is important to know that the duration of action of drugs based on bile acids is no more than three hours, while synthetic analogues prolong the effect to six to seven hours. Another advantage of synthetic drugs is the complexity of the action. For example, the drug "Oxafenamide" has not only a choleretic effect, but also lowers the total level of cholesterol in the blood. Cholagogue preparations based on medicinal plants have not only a long and persistent effect, but also have a hepatoprotective effect on the structure of the liver.

Influencing the mucous membranes of the duodenum, cholekinetics activate the production and release into the blood of the hormone (cholecystokinin), which leads to an increase in the contractile activity of the gallbladder. Normally contracting gallbladder prevents the possibility of stagnation of bile, its penetration into the blood, and also prevents the formation of stones in the ducts and the gall bladder itself.

It should be noted that cholagogue is used not only for therapeutic purposes, but also as a preparation for conducting diagnostic manipulations (for example, duodenal sounding).

Among the main contraindications to the use of choleretics and cholekinitis are acute inflammatory diseases of the liver. In addition, the administration of cholagogue medications to patients with dystrophic disturbances of the hepatic tissue (fibrosis and cirrhosis of the liver) is contraindicated .

Thus, today there is a whole list of various medications to eliminate stagnant phenomena in the gallbladder, which allows the doctor to choose the medicine that is most suitable and highly effective in this particular case.