"Bactroban" preparation: reviews, instruction

Is the drug "Bactroban" (ointment) effective? Instructions, reviews of those who have ever used this tool will be described in this article. In addition, you will find out what is included in the medicine, for what purpose it is prescribed, whether it has side effects and contraindications.

Composition, description and packaging of a local remedy

What components does the "Bactroban" ointment contain? The doctors' comments say that the composition of this medication includes such an active substance as mupirocin. It also contains auxiliary ingredients in the form of macrogol 400 and macrogol 3350.

A white or almost white ointment of a uniform texture is produced in aluminum tubes with a sharp tip that are contained in cardboard boxes.

Pharmacological action of a local drug

What is the drug "Bactroban"? Instruction, expert reviews report that this is an antibiotic, which has a wide range of effects. Ointment is intended for local and external use. Its active substance is produced by a microorganism such as Pseudomonas fluorescens.

The drug in question is capable of inhibiting protein synthesis in bacterial cells. This occurs through a reversible bond with isoleucyl-tRNA synthetase.

When mupirocin is used in minimal concentrations, it is able to have a bacteriostatic effect, and at higher bactericidal effects.

Due to the unique chemical structure and special mechanism of action, there is no cross-resistance between this drug and other antibiotic agents.

At observance of dosages of a preparation the risk of formation of resistant strains of microorganisms is rather small.

Pharmacokinetic parameters

Is the drug "Bactroban" absorbed? The reviews say that with local and external use, this medication practically does not penetrate through the covers of the skin.

In the event that the ointment was applied to the damaged area, it can be slightly absorbed and metabolized to an inactive metabolite, such as monic acid.

The active substance of the drug is quickly removed from the body along with the urine.

Indications for use

For the treatment of which diseases is the drug "Bactroban" used? The opinions of experts speak of the following testimonies:

• Secondary skin infections: infected trauma (insect bites or abrasions), infected eczema, and minor burns and wounds that do not require hospitalization of the patient.
• Primary skin infections: folliculitis, impetigo, ecthyma and furunculosis (for example, furuncles of the auricles, furuncles of the external auditory canal).
• Bacterial lesions (for prevention) and their complications, which arose due to small cuts and wounds.

What other purposes can the drug "Bactroban" be used for? Ointment nasal, reviews about which are only positive, is actively used in otorhinolaryngological practice with staphylococcal infections of the nasal cavity.

Contraindications

What are the contraindications for the use of the drug "Bactroban"? The doctors' comments say that this medication should not be used with the patient's hypersensitivity to the drugs.

Also, ointment is not prescribed for skin lesions and nasal mucosa.

According to the attached instructions, the drug in question is not recommended for use during fetal and during breastfeeding.

If there are severe disorders of the renal system (congenital anomalies, insufficiency), the drug "Bactroban" is prescribed with special caution, assessing possible risks and long-term consequences.

How should I use "Bactroban" ointment?

The doctors' comments indicate that this medication should be used topically three times a day. A small amount of the drug is applied to the affected skin, and a gauze bandage is applied on top (if necessary).

The duration of therapy with such medication is ten days (no more), depending on the extent of the lesion.

In the event that the therapeutic result is absent after a lapse of five days, it is necessary to consult a doctor who is required to review the treatment tactics, taking into account the dynamics of clinical indicators.

Can children be used?

According to the instruction, there are no restrictions for the use of this drug in children. However, it should be noted that the safety and effectiveness of the ointment was studied only in patients from two months of life (within the framework of clinical fundamental programs).

In people with impaired liver function, as well as the elderly, correction of the dosing regimen is not required.

After using the medication, wash hands thoroughly with soap and water.

Side effects

What side effects does the drug "Bactroban" (nasal) cause? The doctors' comments say that this medication can contribute to burning and itching at the application site, as well as erythema, dry skin, swelling and contact dermatitis.

It is extremely rare ointment "Bactroban" causes such allergic reactions to the skin, as a rash and swelling.

Drug Interactions

According to the instructions, "Bactroban" ointment should not be combined with other medicines intended for external use. This is associated with the risk of its dilution and, as a consequence, a decrease in its antibacterial activity.

Breastfeeding and pregnancy

Currently, there is no information about how the drug in question affects the development of the fetus. Therefore, it can be used during pregnancy only if the probable benefit to the mother exceeds the possible risk for the baby.

Excretion of "Bactroban" together with breast milk is unlikely. However, use this medication during lactation should be only as directed by the doctor.

Special Recommendations

Do not apply ointment in the area of drainage and mucous membranes.

Avoid contact with the eye, otherwise wash with water.

In case of allergic reactions or significant irritation of the skin, treatment with ointment should be stopped, and the affected area should be thoroughly rinsed with water until the drug is completely removed. After this, you need to see a doctor who is required to prescribe an alternative therapy.

As with other antibacterial agents, prolonged use of the ointment can lead to an increase in the number of insensitive bacteria.

Cost and analogy

How much does the "Bactroban" ointment cost? The price of a 2% drug (15 g) is about 390 rubles. As for the nasal drug, its cost is slightly higher (about 580 rubles for 3 g).

You can replace the medicine in question with one of the following drugs: "Bonderm", "Supirocin", "Mupirocin", "Supirocin-B".

Patient Reviews

What do patients say about such a drug as "Bactroban"? Reviews (from acne this medication helps very well) report that the drug in question effectively manifests itself in any infectious diseases of the skin. To achieve a therapeutic result, a small amount of the drug is required, which should be applied to the affected area within a short period of time.

Also, the ointment "Bactroban" is used as a nasal agent for the treatment of staphylococcal infection in the nasal cavity. In this case, the drug is applied directly to the nasal passages and evenly distributed with a finger or a cotton swab.

As for negative messages, they are extremely rare. Of those that are available, you can highlight reviews associated with the high cost of the drug. Although experts note that the price of the medication in question fully corresponds to its quality.