What helps "Sulgin"? Indications for use, instructions, reviews

What is the Sulgin medicine? What helps, how to take this remedy? The answers to all the questions you ask are found in this article.

Form, composition

Before you tell us about what helps "Sulgin", you should tell us in what form this drug goes on sale. This medication can be purchased in the form of tablets, the active ingredient of which is sulfaguanidine, and additional substances - primogel, calcium stearate and starch.

Features of the medicine

The drug "Sulgin" from what helps? According to the attached instructions, this remedy has antidiarrheal and antibacterial action. It is highly active against gram-negative and gram-positive bacteria, including intestinal pathogens.

The medicament in question is rather poorly absorbed when administered orally. It operates mainly in the lumen of the intestine.

The active substance of this drug - sulfaguanidine - inhibits dihydropteroate synthetase and competes for receptors with p-aminobenzoic acid. This effect of this component leads to a delay in the biological synthesis of tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidines in the cells of the pathogen.

What helps "Sulgin"

Specialists indicate the following indications of the means under consideration:

• Bacterial dysentery;
• Colitis or enterocolitis with signs of diarrhea;
• Preoperative preparation for surgical interventions on the intestine.

Medication "Sulgin" from what helps? Tablets for oral administration are often used in the presence of carriers of typhoid fever or dysentery or suspected of it.

Mode of application

Now you know what helps "Sulgin". How should this medication be used correctly? In acute intestinal infections, this agent must be taken orally. On the first day of therapy, appoint 1-2 g to 6 times a day. As for the second and third days, the indicated dosage is preserved, however, the frequency of reception is reduced to 5 times a day. On the fourth and fifth day the frequency of application of this drug in a dose of 1-2 g is up to 4 and up to 3 times a day, respectively.

The duration of treatment with this medication should not exceed more than two weeks. Children up to 3 years of age are recommended to take 200 mg of the drug per kg of body weight per day (divide by three times) within one week.

Babies of 3 years of age give 400-750 mg of funds up to 4 times a day.

In the course of carrying out preventive measures for postoperative complications, patients are recommended to take 50 mg of medication per kg of weight three times a day for 5 days before the intervention, and then for another week after the operation.

Side effects

Finding out what helps "Sulgin", it is necessary to get acquainted with its side effects. According to the instruction, after application of this remedy, the following negative effects are often observed in patients:

• Depression, myalgia, headache, necrolysis, apathy, photosensitivity, tremor;
• Rash, dizziness, itching, neutropenia, nausea, thrombocytopenia, gastritis, agranulocytosis, cholestasis, anemia;
• Fever, bronchospasm, vomiting, arthralgia, diarrhea, crystalluria, anorexia, polyuria;
• Glossitis, increased urea concentration, stomatitis, toxic nephropathy, erythema polymorphous-bullous;
• Increased transaminase concentration, kidney damage, hepatitis, hematuria, interstitial nephritis, myocarditis toxic allergic;
• Oliguria, hypercreatininaemia, epidermal edema angioedema, anuria.

Cases of overdose

When taking higher doses of Sulgin, symptoms that are characteristic of all sulfanilamide drugs (for example, vomiting, fainting, nausea, dizziness, intestinal colic, fever, headache, depression, hematuria, crystalluria) may occur.

Treatment of such conditions is carried out by canceling the medicine, as well as rinsing the stomach, drinking plenty and forced diuresis.

Recommendations

In case of acute necessity, the medicament in question can be used together with other antibacterial agents and sulfonamides, which are well absorbed from the intestine.

In the process of treatment, "Sulgin" is recommended to intensify diuresis, and also to take in parallel vitamins of group B.

Consumer Reviews

Most patients who take the drug "Sulgin", are satisfied with its curative effect. They argue that this remedy is good and quickly enough to eliminate all symptoms of intestinal poisoning, including diarrhea.

Despite all the positive feedback, it should be noted that sulfaguanidine, as well as medicines based on it, have long been banned in developed countries because of their extreme nephrotoxicity.