TTG lowered - what does it mean? TTG is lowered at pregnancy

And gynecologists, and endocrinologists well know how important it is to monitor the hormone levels in a woman, especially during pregnancy. At this time, almost all organs and body systems change the course of their work, tuning in a new way. After all for nine months, their main task will be to ensure the normal development of the child and maintain a healthy state of the future mother. Of course, these changes and the functioning of the thyroid gland are affected. Violation of the level of hormones produced by it, largely affects the development and course of pregnancy.

The level of hormone TTG allows you to find out whether the pregnancy is normal or there are any deviations. This indicator is determined by the analysis of blood taken from the vein. If TSH is lowered or, conversely, is elevated, the doctor will prescribe additional studies. They will help to find out what caused the deviation of hormone levels from normal.

What is TTG?

To know what is at issue, you need to consider the hormones that are produced by the human thyroid gland. Thyotropic hormone is responsible for the normal operation of the anterior part of the pituitary gland. It controls the development and functioning of the thyroid gland, as well as the production of triiodothyronine (T3) and thyroxine (T4). These hormones are very important for the normal functioning of the sexual and cardiovascular systems, participate in metabolic processes and affect the psychoemotional state of a person.

Why study the level of TSH?

Any fluctuations in the amount of hormones in the blood can cause a variety of adverse health consequences. It is very important to keep under control all relevant indicators during the bearing of the child. Often there are situations when the hormonal background changes during this period. Happens, that TTG it is lowered at pregnancy. It is especially important to pay attention to such fluctuations, if a woman has previously experienced with thyroid diseases or had a sad experience associated with miscarriage or fading of the fetus.

The fact is that this hormone reacts very sensitively to pathological changes in the endocrine system. This is due to one of the basic rules of medicine - the principle of negative feedback. If TTG is lowered, what does it mean? This indicates an increase in the level of free thyroxin. Conversely, with an increase in TSH, T4 decreases. Thus, knowing the main parameters of hormones produced by the thyroid gland, you can monitor the health of a woman, especially in an "interesting" position.

Norms of TTG in pregnancy

The level of thyroid-stimulating hormone, determined by ELISA (enzyme immunoassay) in a woman's blood, should be from 0.4 to 4 mU / liter. During pregnancy, these indicators may slightly deviate from the norm. During this period, the level of TSH is constantly changing. Therefore, it is very difficult to derive any average parameters to which it must correspond. It is believed that the most severe TSH is downgraded for a period of 10-12 weeks. But there are cases when it remains low throughout the nine months. Quite often TTG is lowered at a multiple pregnancy. However, minor deviations from the norm both in one and the other side are not considered pathology.

Influence of hormones produced by the thyroid gland on pregnancy

The endocrine system plays an important role. The thyroid gland produces triiodothyronine and thyroxine, and this process is controlled by the pituitary gland. In its anterior lobe, TSH is produced, which controls the T3 and T4 levels. Together with the blood flow, they fall into almost all cells of the human body and take an active part in their life.

The main function of triiodothyronine and thyroxine is the regulation and maintenance of basic metabolism. These hormones contribute to the regulation of cellular reproduction. During pregnancy, they have a stimulating effect on the yellow body, preventing the probability of miscarriage at an early age. Just like T3 and T4 affect the female body, they are involved in the development of the fetus, especially in the formation of the brain.

Now that we know the importance of the normal level of hormones produced by the thyroid gland, for the mother and the unborn child, we can understand why it is necessary to monitor the parameters of thyroxine and triiodothyronine. The doctor should alert the situation when T4 is lowered (and TTG is elevated). In this case, a detailed study is assigned.

TTG in planning pregnancy

It would be a mistake to believe that the study of the hormonal background is important only when the woman is already carrying the child under the heart. As mentioned earlier, thyroxine, triiodothyronine and TSH play an important role in the state of human health. They also affect the reproductive system. So, if the hormone TSH is lowered, it's not very scary. But if his level is raised simultaneously with a decrease in T3 and T4, the doctor may assume a malfunction of the ovaries. And this, in turn, leads to a decrease in the probability of conceiving and bearing a child.

The processes of production of follicles, the formation of the ovum and the yellow body are disturbed. Therefore, if a woman seeks a doctor with complaints about the inability to become pregnant, the endocrinologist must prescribe an analysis for thyroid hormones. Ideal index in the planning of conception is the level of TSH, equal to 1.5 μIU / ml. This is the average level for an adult.

TTG is lowered: what does it mean?

Unfortunately, it rarely happens that all tests are normal. Most often at least one of them, but has deviations. For example, TTG is lowered. What does it mean? As a rule, such a result of the tests should not alert the doctor. A slight decrease in the production of this hormone during pregnancy is absolutely normal. But in some cases this may be a consequence of pathological conditions:

1. If TSH is lowered during pregnancy, it is necessary to check the work of the pituitary gland.
2. There is a small chance of Plummer's syndrome.
3. Benign tumors of the thyroid gland.
4. Necrosis of the pituitary gland after childbirth.
5. Increased level of hormones produced by the thyroid gland.
6. Nervous overexcitation and overstrain.

Thus, if you are wondering "TTG is lowered, what does it mean", do not look for information in the literature, it is better to immediately contact the endocrinologist. He will find out the cause of the changes and prescribe adequate treatment.

If TSH is lowered, a woman may notice some symptoms, for example, headache, heart palpitations, fever and upset stomach. But more often than not, such changes occur almost asymptomatically.

TTG elevated

If the tests showed that the level of this hormone during pregnancy is increased, then doctors can prescribe several additional studies, since this may be a sign of the following conditions:

1. The adrenal gland is broken.
2. There are mental illnesses.
3. Problems with the pituitary gland.
4. Increased thyroid hormone levels.
5. Pituitary tumor.
6. Renal insufficiency.
7. Gestosis in the severe stage.

Symptoms of increased TSH are low temperature, weakness, general fatigue, insomnia, pallor and poor appetite. Visually the neck looks thickened.

Hormone T4: rates and abnormalities

The thyroxine is closely connected with TTG, therefore usually appoint or nominate analyzes on research of their level in aggregate. T4 is one of the most important stimulators of cell division and regeneration in the body. The weight of a person largely depends on its quantity, since thyroxine is able to influence the metabolic processes and protein synthesis. It is this hormone that determines the body's need for vitamins, and also improves the digestibility of carotene by the liver. In addition, it lowers the level of cholesterol in the blood and prevents the appearance of plaques in the vessels of the brain. It is also very important for the work of the female reproductive system. In cases where the T4 level is lowered or elevated, there are often problems with the planning and course of pregnancy.

The thyroxine norm is 9-22 picomoles per liter. These indicators are applicable only to women, as they are higher in men. Not always a deviation from the norm is a symptom of a serious illness, perhaps, the body experienced temporary malfunctions. If you undergo a course of treatment, then the probability of bearing and giving birth to a healthy baby is very high.

The relationship between TTG and T4

Indicators of the level of hormones that are produced by the thyroid gland, closely intertwined. There are situations when TTG is down, T4 is elevated. With normal operation of the pituitary and thyroid gland this should not be. Usually, if TSH is lowered, T4 is normal. This means that thyroxin suppresses thyrotropin production too much.