The medicine 'Tinidazole'. Instructions for use

The medicine "Tinidazole" is considered quite effective and fast acting. The undoubted advantage of the drug is its affordable cost.

The drug "Tinidazole" instructions for use refers to protivoprotozoed. It is used to treat diseases caused by protozoa. Characterizing the drug "Tinidazole", the instruction for use indicates the ability to inhibit synthesis and damage the DNA structure of pathogens.

The medicine has a high level of absorption. Its bioavailability is about one hundred percent. Medication "Tinidazol" is able to penetrate the placental and blood-brain barrier. After intake for seventy-two hours is allocated with the milk of a nursing woman. Metabolized (breaks down) into pharmacologically active hydroxylated derivatives, which can suppress the development of anaerobic microbes.

Half of the accepted dose of the drug is excreted with bile, about twenty-five percent (unchanged) and twelve percent (in the form of decay products) is excreted by the kidneys.

The medicine "Tinidazole". Indications for use

The drug is prescribed for amebiasis (with hepatic form including), giardiasis, trichomoniasis. In infections associated with anaerobic bacteria, with mixed aerobic-anaerobic infections, a medication "Tinidazole" is also prescribed. The use in this case is recommended in combination with antibiotic drugs and bismuth preparations.

Also, a drug is prescribed and as a prophylaxis for anaerobic infections in the postoperative period.

Dosage regimen

The dose of the drug is determined individually. The drug "Tinidazole" instructions for use recommends adults take once in an amount of 1.5-2 grams per day, children - also once a day for 50-75 mg / kg (except for the prevention of anaerobic infections in the postoperative period). Duration of application can be up to ten days.

Contraindications to the appointment of the drug "Tinidazole" instructions for use include the pathology of the central nervous system of organic nature, hypersensitivity, a disorder of the function of hematopoiesis.

The drug is not recommended in the first trimester of pregnancy. Its use in other periods of gestation is allowed on the recommendation of a specialist, taking into account the risk-benefit ratio. If you need to use the drug "Tinidazole" during lactation should stop breastfeeding.

When taking medication, there may be some side effects. In particular, nausea, diarrhea, vomiting, metallic taste, dryness of the oral mucosa, anorexia may appear. In some cases there is a disorder of coordination of movements, dizziness, fatigue, weakness, convulsions, peripheral neuropathy, dysarthria, headache. Also, adverse events include angioedema, transient leukopenia, itching and rash on the skin, hives.

special instructions

With trichomoniasis therapy, both partners must be exposed.

In case of negative manifestations from the side of the central nervous system (headaches, coordination disorder, peripheral neuropathy and others), the drug "Tinidazole" should be stopped immediately.

During the treatment should refrain from taking alcohol.

The medicine "Tinidazole" affects the color of urine, making it dark.

With a therapeutic course for more than six days, systematic monitoring of the peripheral blood state is necessary.

Children up to twelve years of use of the drug to prevent the development of anaerobic infections is not recommended (in view of the lack of prescribed dosages).

Before taking medication "Tinidazole" you should consult a doctor.